Optimizing the management of smoking patients with acute rhinosinusitis
https://doi.org/10.21518/2079-701X-2020-16-128-132
Abstract
Introduction. Viral infection is the main cause of damage to the ciliated epithelium of the nasal cavity mucosa, which in turn leads to disruption of mucociliary transport, increased viscosity and mucus hypersecretion in the sinuses and deceleration of its evacuation. Smokers suffer from chronic obstructive pulmonary diseases, in particular obstructive bronchitis. Their cough symptom complex sharply increases in acute respiratory viral infection (ARVI), especially when the mucociliary airway system is affected. The etiotropic treatment of this combined pathology is a therapy capable of affecting the entire mucociliary system of the upper and lower respiratory tract, including a drug based on ivy leaf extract, with the active ingredient of the saponin group.
Aim of the study. To determine the effectiveness of phytopreparation in preventing exacerbation of chronic bronchitis of smokers in patients with acute viral rhinosinusitis.
Materials and methods. Complex examination of 20 active smokers suffering from acute viral rhinosinusitis (AVR), including computed tomography of the lungs, was conducted. The randomized study included the use of phytopreparations in the complex therapy of acute rhinosinusitis in patients with obstructive bronchitis.
Results and discussion. Use of medicines based on ivy extract in the complex treatment of acute rhinosinusitis in smokers allowed to achieve reduction of AVR symptom complex complicated by exacerbation of chronic bronchitis by the 5th day of the disease. Dynamics of cough complaints reduction in comparison groups reflects the beneficial effect of ivy extract in smokers with ARVI, complicated by AVR, and in the absolute majority of cases allows avoiding bacterial complications.
Conclusion. The conducted study proved the effectiveness of Gedelix in the complex treatment of viral acute rhinosinusitis in smokers. In the absolute majority of cases (80% of the total number of patients in the group) it was possible to avoid long-term exacerbation of chronic bronchitis and bacterial complications.
About the Authors
T. I. GarashchenkoRussian Federation
Tatiana I. Garashchenko, Dr. of Sci. (Med.), Professor, Academic Secretary, Federal State Budgetary Institution “Scientific and Clinical Center of Otorhinolaryngology of the Federal Medico-Biological Agency of the Russian Federation”; Professor of the Department of Otorhinolaryngology, Faculty of Additional Professional Education, Federal State Autonomous Educational Institution of Higher Education “Pirogov Russian National Research Medical University” of the Ministry of Health of the Russian Federation
1, Ostrovityanov St., Moscow, 117997,
30, Bldg. 2, Volokolamskoe Shosse, Moscow, 123182
I. U. Serebryakova
Russian Federation
Irina U. Serebryakova, Cand. of Sci. (Med.), Leading Researcher in the Office of the Academic Secretary
1, Ostrovityanov St., Moscow, 117997
K. Sh. Davudov
Russian Federation
Khasan Sh. Davudov, Dr. of Sci. (Med.), Professor, Deputy Director
1, Ostrovityanov St., Moscow, 117997
A. S. Korobkin
Russian Federation
Artyom S. Korobkin, Cand. of Sci. (Med.), Head of the Scientific and Clinical Department of Radiation Diagnostics
1, Ostrovityanov St., Moscow, 117997
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Review
For citations:
Garashchenko TI, Serebryakova IU, Davudov KS, Korobkin AS. Optimizing the management of smoking patients with acute rhinosinusitis. Meditsinskiy sovet = Medical Council. 2020;(16):128-132. (In Russ.) https://doi.org/10.21518/2079-701X-2020-16-128-132