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Cough in children: the most common problem in pediatrics

https://doi.org/10.21518/2079-701X-2020-18-53-57

Abstract

Cough is a common problem in childhood, which leads to frequent paediatrician visits, affects the quality of life, and causes material losses to the family and society. In pediatric practice, cough is most often associated with acute respiratory infections, which can develop in children up to 5–8 times a year. 50–70% of children under 1 year old and 30–60% of school age children visit pediatricians with this problem. Examination of patients with cough shows that the most common causes of recurrent cough may include bronchial asthma, lingering bacterial bronchitis, chronic ENT diseases, gastroesophageal reflux, as well as bronchial reactivity after respiratory syncytial,  rhinovirus or pertussis infections. Mucociliary clearance in children may decrease under the influence of external factors, which contributes to the development of infections. The effectiveness of cough in children, especially young children, depends on the severity of the cough reflex, bronchial patency, viscosity of bronchial secretion. The choice of therapy to treat cough should take into account the age and etiology of the cough. The inappropriate antibiotic therapy for prolonged cough increases the risk of developing antibiotic resistance. Due to  potential side effect in the form of respiratory depression and opioid toxicity, codeine-containing drugs are not  recommended for use in children under 12 years of age. An alternative to cough drugs is herbal medicines with compound effect: anti-inflammatory, bronchodilator, expectorant and mucolytic.

About the Authors

S. B. Krutikhina
N.F. Filatov Clinical Institute of Children’s Health, Federal State Autonomous Educational Institution of Higher Education “Sechenov First Moscow State Medical University” of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation

Cand. of Sci. (Med.), Teaching Assistant of the Department of Childhood Diseases

8, Bldg. 2, Trubetskaya St., Moscow, 119991, Russia



A. V. Meleshkina
N.F. Filatov Clinical Institute of Children’s Health, Federal State Autonomous Educational Institution of Higher Education “Sechenov First Moscow State Medical University” of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation

Cand. of Sci. (Med.), Associate Professor of the Department of Childhood Diseases

8, Bldg. 2, Trubetskaya St., Moscow, 119991, Russia



E. A. Yablokova
N.F. Filatov Clinical Institute of Children’s Health, Federal State Autonomous Educational Institution of Higher Education “Sechenov First Moscow State Medical University” of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation

Cand. of Sci. (Med.), Associate Professor of the Department of Childhood Diseases

8, Bldg. 2, Trubetskaya St., Moscow, 119991, Russia



References

1. Thompson M., Cohen H.D., Vodicka T.A., Blair P.S., Buckley D.I., Heneghan C., Hay A.D. Duration of symptoms of respiratory tract infections in children: systematic review. BMJ. 2013;347:f7027. doi: 10.1136/bmj.f7027.

2. Jurca M., Ramette A., Dogaru C.M., Goutaki M., Spycher B.D., Latzin P. et al. Prevalence of cough throughout childhood: A cohort study. PLoS One. 2017;12(5):e0177485. doi: 10.1371/journal.pone.0177485.

3. Safina A.I. Coughing in children with colds: efficacy and new possibilities for phytotherapy. Meditsinskiy sovet = Medical Council. 2019;(2):90–94. (In Russ.) doi: 10.21518/2079-701X-2019-2-90-94.

4. Chang A.B., Robertson C.F., Van Asperen P.P., Glasgow N.J., Mellis C.M., Masters I.B. et al. A multicenter study on chronic cough in children: burden and etiologies based on a standardized management pathway. Chest. 2012;142(4):943–950. doi: 10.1378/chest.11-2725.

5. Chen X., Peng W.-S., Wang L. Etiology analysis of nonspecific chronic cough in children of 5 years and younger. Medicine. 2019;98(3):e13910. doi: 10.1097/MD.0000000000013910.

6. Usta Guc B., Asilsoy S., Durmaz C. The assessment and management of chronic cough in children according to the British Thoracic Society guidelines: descriptive, prospective, clinical trial. Clin Respir J. 2014;8(3):330–337. doi: 10.1111/crj.12076.

7. Bustamante-Marin X.M., Ostrowski L.E. Cilia and Mucociliary Clearance. Cold Spring Harb Perspect Biol. 2017;9(4):a028241. doi: 10.1101/cshperspect.a028241.

8. Ilenkova N.A. Cough in children: causes, diagnostic approaches, treatment. Pediatriya (Pril. k zhurn. Consilium Medicum) = Pediatrics (Suppl. Consilium Medicum). 2018;(1):57–62. (In Russ.) doi: 10.26442/2413-8460_2018.1.57-62.

9. Geppe N.A., Dronov I.A., Baiandina G.N. Approaches to Treating Acute Respiratory Infections in Children. Doktor. Ru = Doctor.Ru. 2017;(4):14–18. (In Russ.) Available at: https://www.journaldoctor.ru/upload/iblock/598/2.pdf.

10. Kosenkova T.V. Features of mukolitiс therapy in pediatric practice. Voprosy prakticheskoi pediatrii = Clinical Practice in Pediatrics. 2016;11(4):54–59. (In Russ.) doi: 10.20953/1817-7646-2016-4-54-59.

11. Prentice B., Jaffé A. Antibiotics for prolonged wet cough in children. J Paediatr Child Health. 2019;55(1):110–113. doi: 10.1111/jpc.14300.

12. Gardiner S.J., Chang A.B., Marchant J.M., Petsky H.L. Codeine versus placebo for chronic cough in children.Cochrane Database Syst Rev. 2016;(7):CD011914. doi: 10.1002/14651858.CD011914.pub2.

13. Smith S., Schroeder K., Fahey T. Over-the-counter (OTC) medications for acute cough in children and adults in community settings. Cochrane Database Syst Rev. 2014;(11):CD001831. doi: 10.1002/14651858.CD001831.pub5.

14. Shields M., Bush A., Everard M., McKenzie S., Primhak R. Recommendations for the assessment and management of cough in children. Thorax. 2008;63(S3):1–15. doi: 10.1136/thx.2007.077370.

15. Oduwole O., Meremikwu M.M., Ouo-Ita A., Udoh E.E. Honey for acute cough in children. Cochrane Database Syst Rev. 2012;(3):CD007094. doi: 10.1002/14651858.CD007094.pub3.

16. Paediatric Formulary Committee. BNF for Children (BNFC) 2018–2019. 1120 p. Available at: http://infinity.wecabrio.com/857113364-bnf-for-children-bnfc-2018-2019.pdf.

17. Zaitseva O.V. Cough in children: rational choice of therapy. Meditsinskiy sovet = Medical Council. 2016;(16):68–72. (In Russ.) doi: 10.21518/2079-701X-2016-16-68-72.

18. Ruzhentsova T.A, Budakovskaya A.V., Gorelov A.V. Phytotherapy in the treatment of acute respiratory infections in children. RMZH = RMJ. 2014;(21):1538. (In Russ.) Available at: https://www.rmj.ru/articles/pediatriya/Fitoterapiya_v_lechenii_ostryh_respiratornyh_infekciy_u_detey.

19. Mastalerz-Migas A., Doniec Z., Płusa T. Bronchipret TE® in therapy of acute infections of the respiratory tract. Pol Merkur Lekarski. 2017;43(258):255–257. (In Polish) Available at: https://pubmed.ncbi.nlm.nih.gov/29298963.

20. Marzian O. Treatment of acute bronchitis in children and adolescents. Noninterventional postmarketing surveillance study confirms the benefit and safety of a syrup made of extracts from thyme and ivy leaves. MMW Fortschr Med. 2007;149(27–28S):69–74. (In German) Available at: https://pubmed.ncbi.nlm.nih.gov/17619603.

21. Ismail C., Willer G., Steindl H. Bronchipret and synthetic mucolytics in acute bronchitis: a comparative cohort study. Farmateka = Farmateka. 2005;19(114):86–90. (In Russ.) Available at: https://pharmateca.ru/ru/archive/article/6365.


Review

For citations:


Krutikhina SB, Meleshkina AV, Yablokova EA. Cough in children: the most common problem in pediatrics. Meditsinskiy sovet = Medical Council. 2020;(18):53-57. (In Russ.) https://doi.org/10.21518/2079-701X-2020-18-53-57

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)