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Medical castration in the treatment of widespread cancers of the prostate. The role of buserelin

https://doi.org/10.21518/2079-701X-2014-8-30-33

Abstract

Medical castration with LHRH agonists is a significant trend in the treatment of locally advanced and metastatic prostate cancer (PC). The article is devoted to the effectiveness of synthetic LHRH agonist buserelin (Buserelin-depo) in the treatment of patients with hormone dependent PC. Administration of Buserelin-depot results in a decrease of the prostate-specific antigen levels, stable reduction of serum testosterone to postcastration level, reduction in the size of the prostate and fewer voiding dysfunction symptoms without any serious side effects.

About the Authors

SV Mishugin
ГБУЗ ГКБ №57, г. Москва
Russian Federation


AA Mordovin
ГБУЗ ГКБ №57, г. Москва
Russian Federation


AA Gritskevich
Краевой онкологический диспансер, г. Краснодар
Russian Federation


IG Rusakov
ГБУЗ ГКБ №57, г. Москва
Russian Federation


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Review

For citations:


Mishugin S, Mordovin A, Gritskevich A, Rusakov I. Medical castration in the treatment of widespread cancers of the prostate. The role of buserelin. Meditsinskiy sovet = Medical Council. 2014;(8):30-33. (In Russ.) https://doi.org/10.21518/2079-701X-2014-8-30-33

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)