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Skin bacterial infections – always a topical problem

https://doi.org/10.21518/2079-701X-2021-8-63-66

Abstract

Bacterial skin infections are one of the most common reasons for visiting a dermatologist. A huge number of different microor-ganisms live on the human skin, but sometimes due to some external and internal factors the balance is disturbed, which leads to the predominance of one or more colonies and the subsequent development of the infection. Often staphylococci or streptococci are the cause of pyodermias (this is how skin bacterial infections are usually called). In the treatment of pyodermias, local antibacterial drugs are most often used. But given the free access to antibiotics and their thoughtless use, the sensitivity of many strains of microorganisms to the effects of drugs is reduced, which in many cases makes treatment difficult. According to various data, the sensitivity to fusidic acid remains very high, which makes fusidic acid-based drugs an optimal choice for therapy of bacterial infections. It is worth noting that recent studies have also demonstrated the anti-inflammatory activity of fusidic acid, which has a positive effect on the effectiveness of therapy. In today’s realities, the problem of bacterial skin infections remains as urgent as ever. Prolonged use of personal protective equipment and, in particular, medical masks creates ideal conditions for increased growth of opportunistic microorganisms. In this article, we present a case from our own practice. Impetigo developed in a patient after improper use of personal protective equipment. Fusidic acid topical therapy achieved a good clinical result after only 7 days. Thus, given the prevalence of pyodermias, fusidic acid-based drugs may be the optimal solution to the problem.

About the Authors

A. L. Piruzyan
Center for Theoretical Problems of Physical and Chemical Pharmacology of the Russian Academy of Sciences
Russian Federation

Anastas L. Piruzyan, Dr. Sci. (Med.), Professor, Leading Researcher

30, Srednyaya Kalitnikovskaya St., Moscow, 109029



Z. A. Niewozinska
Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology
Russian Federation

Zofia A. Niewozinska, Cand. Sci. (Med.), dermatovenerologist

20, Seleznevskaya St., Moscow, 127473



I. M. Korsunskaya
Center for Theoretical Problems of Physical and Chemical Pharmacology of the Russian Academy of Sciences
Russian Federation

Irina M. Korsunskaya, Dr. Sci. (Med.), Professor, Head of Laboratory

30, Srednyaya Kalitnikovskaya St., Moscow, 109029



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Review

For citations:


Piruzyan AL, Niewozinska ZA, Korsunskaya IM. Skin bacterial infections – always a topical problem. Meditsinskiy sovet = Medical Council. 2021;(8):63-66. (In Russ.) https://doi.org/10.21518/2079-701X-2021-8-63-66

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)