Psychiatric comorbidity and psycho-emotional status of patients with acne
https://doi.org/10.21518/2079-701X-2022-16-13-38-46
Abstract
Acne is a very common skin disease that has a significant impact on the psycho-emotional status of patients. This disease affects various areas of patients’ lives, leading to problems in body image, socialization, and sexuality. The change in appearance and the psycho-emotional stress associated with the development of acne can also affect other aspects of patients’ lives, including educational attainment, social activity, and a decline in academic performance and ability to work. Interpersonal problems in acne patients can occur not only with acquaintances and colleagues, but also within the family. The presence of a pronounced cosmetic defect, along with acute psycho-emotional problems, leads to a sharp decrease in quality of life, which is often exacerbated by comorbid psychiatric pathology: anxiety, depression, dysmorphophobia, self-injurious behavior, which certainly requires timely, effective and safe therapy for the underlying skin disease. Isotretinoin is an effective medication for the treatment of severe and treatment-resistant forms of acne. This drug has an effect on all four pathophysiological factors of acne development. Isotretinoin reduces sebum production, regulates hyperkeratosis in the estuaries of sebaceous follicles, reduces the number of Propionibacterium acnes on the skin and is thought to have certain immunological and anti-inflammatory effects. This is why the introduction of this drug into clinical practice has been recognized as an incredible triumph in the treatment of vulgar acne. However, the presence of some undesirable side effects may limit its widespread use. In 1982, for example, the FDA issued a warning about the possible risk of depression and the occurrence of suicidal thoughts and attempts while using isotretinoin. However, this warning was not subsequently confirmed.
About the Authors
E. V. Dvoriankova
Center for Theoretical Problems of Physico-Chemical Pharmacology of the Russian Academy of Sciences;
Medical Family Center “Pangea”
Russian Federation
Russian Federation
Dr. Sci. (Med.), Leading Researcher at the Laboratory of Physico-Chemical and Genetic Problems of Dermatology, 30, Srednyaya Kalitnikovskaya St., Moscow, 109029;
Dermatologist, 5, Bldg. 8, Bolshaya Cherkizovskaya St., Moscow, 107061
N. A. Shevchenko
Center for Сomprehensive Rehabilitation of Disabled People “Butovo”
Russian Federation
Russian Federation
Мedical Рsychologist,
42, Polyana St., Moscow, 117042
O. V. Zhukova
Peoples’ Friendship University of Russia;
Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology
Russian Federation
Russian Federation
Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenerology, Allergology and Cosmetology of the Medical Institute, 6, Miklukho-Maklai St., Moscow, 117198;
Сhief Мedical Оfficer, 17, Leninskiy Ave., Moscow, 119071
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Review
For citations:
Dvoriankova EV, Shevchenko NA, Zhukova OV. Psychiatric comorbidity and psycho-emotional status of patients with acne. Meditsinskiy sovet = Medical Council. 2022;(13):38-46. (In Russ.) https://doi.org/10.21518/2079-701X-2022-16-13-38-46
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