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The role of thrombocytopenia in the clinical management of patients with liver cirrhosis: opinion of experts in therapeutic and surgical hepatology

https://doi.org/10.21518/2079-701X-2022-16-23-2

Abstract

Seven of the country’s leading  experts  in the field of therapeutic and surgical hepatology answer  questions on this issue: how relevant  is thrombocytopenia in patients with CLD for clinical practice, what  is the  average  proportion  of patients who need correction  of thrombocytopenia before scheduled and emergency  surgical/invasive interventions and how is thrombocytopenia correction  performed. All experts  are unanimous in the opinion that thrombocytopenia is most common at the stage  of cirrhosis. Further, the experts  discussed  the issues of the total number of patients with CLD, the proportion  of patients with thrombocytopenia at all, the proportion  of patients with thrombocytopenia in need of surgical interventions, the experts were asked to provide schemes  for correcting  thrombocytopenia, which they use in their  clinical practice. The focus of the  experts’ attention was on the discussion of patients who have a platelet level of less than 50 000/µl and need scheduled surgical interventions / invasive procedures. All experts  unanimously stratify these  interventions according to the risk of hemorrhagic complications:  high – more than  1.5%, low – less than  1.5%. The most common and available  method  for the correction  of thrombocytopenia at present is platelet transfusion. Details of all this information, as well as statistical data, can be found in this article.

About the Authors

M. V. Maevskaya
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Marina V. Maevskaya - Dr. Sci. (Med.), Professor, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991



E. N. Bessonova
Urals State Medical University; Sverdlovsk Regional Hepatological Center, Sverdlovsk Regional Clinical Hospital No. 1
Russian Federation

Elena N. Bessonova - Dr. Sci. (Med.), Professor, Associate Professor of the Therapy Department, Faculty of Advanced Training and Professional Retraining, Urals State  Medical University; Head of the Regional Hepatological Centre, Sverdlovsk Regional Hepatological Center, Sverdlovsk Regional Clinical Hospital No. 1.

3, Repin St., Ekaterinburg, 620028; 185, Volgogradskaya St., Ekaterinburg, 602102



N. I. Geyvandova
Stavropol State Medical University
Russian Federation

Natalia I. Geyvandova - Dr. Sci. (Med.), Professor, Professor of the Department of Hospital Therapy, Stavropol State Medical University.

310, Mira St., Stavropol, 355017



E. A. Kitsenko
Russian Scientific Center of Surgery named after Academician B.V. Petrovsky
Russian Federation

Evgeniy A. Kitsenko - Dr. Sci. (Med.), Professor, Leading Research Fellow, Russian Scientific Center of Surgery named after Academician B.V. Petrovsky.

2, Abrikosovsky Lane, Moscow, 119991



N. V. Korochanskaia
Regional Clinical Hospital No. 2; Kuban State Medical University
Russian Federation

Natalia V. Korochanskaia - Dr. Sci. (Med.), Professor, Head of the Gastroenterology Centre and Chief Gastroenterologist, Regional Clinical Hospital No. 2; Professor  of Department of Surgery No. 3, Faculty of Advanced Training and Professional  Retraining  of Specialists, Kuban State  Medical University.

6/2, Krasnykh Partizan  St., Prikubansky Intracity District, Krasnodar, Krasnodar Territory, 350012; 4, Mitrofan Sedin St., Krasnodar, 350063



V. G. Morozov
Medical Company “Hepatologist”
Russian Federation

Viacheslav G. Morozov - Dr. Sci. (Med.), Professor, Director of the Medical company “Hepatologist”.

36a, Serdobskaya St., Samara, 443063



Y. V. Khoronko
Rostov State Medical University
Russian Federation

Yury V. Khoronko - Dr. Sci. (Med.), Professor, Head of the Department of Operative Surgery, Rostov State Medical University.

29, Nahichevansky Lane, Rostov-on-Don, 344022



References

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Review

For citations:


Maevskaya MV, Bessonova EN, Geyvandova NI, Kitsenko EA, Korochanskaia NV, Morozov VG, Khoronko YV. The role of thrombocytopenia in the clinical management of patients with liver cirrhosis: opinion of experts in therapeutic and surgical hepatology. Meditsinskiy sovet = Medical Council. 2022;(23):142-147. (In Russ.) https://doi.org/10.21518/2079-701X-2022-16-23-2

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)