The role of thrombocytopenia in the clinical management of patients with liver cirrhosis: opinion of experts in therapeutic and surgical hepatology
https://doi.org/10.21518/2079-701X-2022-16-23-2
Abstract
Seven of the country’s leading experts in the field of therapeutic and surgical hepatology answer questions on this issue: how relevant is thrombocytopenia in patients with CLD for clinical practice, what is the average proportion of patients who need correction of thrombocytopenia before scheduled and emergency surgical/invasive interventions and how is thrombocytopenia correction performed. All experts are unanimous in the opinion that thrombocytopenia is most common at the stage of cirrhosis. Further, the experts discussed the issues of the total number of patients with CLD, the proportion of patients with thrombocytopenia at all, the proportion of patients with thrombocytopenia in need of surgical interventions, the experts were asked to provide schemes for correcting thrombocytopenia, which they use in their clinical practice. The focus of the experts’ attention was on the discussion of patients who have a platelet level of less than 50 000/µl and need scheduled surgical interventions / invasive procedures. All experts unanimously stratify these interventions according to the risk of hemorrhagic complications: high – more than 1.5%, low – less than 1.5%. The most common and available method for the correction of thrombocytopenia at present is platelet transfusion. Details of all this information, as well as statistical data, can be found in this article.
About the Authors
M. V. MaevskayaRussian Federation
Marina V. Maevskaya - Dr. Sci. (Med.), Professor, Sechenov First Moscow State Medical University (Sechenov University).
8, Bldg. 2, Trubetskaya St., Moscow, 119991
E. N. Bessonova
Russian Federation
Elena N. Bessonova - Dr. Sci. (Med.), Professor, Associate Professor of the Therapy Department, Faculty of Advanced Training and Professional Retraining, Urals State Medical University; Head of the Regional Hepatological Centre, Sverdlovsk Regional Hepatological Center, Sverdlovsk Regional Clinical Hospital No. 1.
3, Repin St., Ekaterinburg, 620028; 185, Volgogradskaya St., Ekaterinburg, 602102
N. I. Geyvandova
Russian Federation
Natalia I. Geyvandova - Dr. Sci. (Med.), Professor, Professor of the Department of Hospital Therapy, Stavropol State Medical University.
310, Mira St., Stavropol, 355017
E. A. Kitsenko
Russian Federation
Evgeniy A. Kitsenko - Dr. Sci. (Med.), Professor, Leading Research Fellow, Russian Scientific Center of Surgery named after Academician B.V. Petrovsky.
2, Abrikosovsky Lane, Moscow, 119991
N. V. Korochanskaia
Russian Federation
Natalia V. Korochanskaia - Dr. Sci. (Med.), Professor, Head of the Gastroenterology Centre and Chief Gastroenterologist, Regional Clinical Hospital No. 2; Professor of Department of Surgery No. 3, Faculty of Advanced Training and Professional Retraining of Specialists, Kuban State Medical University.
6/2, Krasnykh Partizan St., Prikubansky Intracity District, Krasnodar, Krasnodar Territory, 350012; 4, Mitrofan Sedin St., Krasnodar, 350063
V. G. Morozov
Russian Federation
Viacheslav G. Morozov - Dr. Sci. (Med.), Professor, Director of the Medical company “Hepatologist”.
36a, Serdobskaya St., Samara, 443063
Y. V. Khoronko
Russian Federation
Yury V. Khoronko - Dr. Sci. (Med.), Professor, Head of the Department of Operative Surgery, Rostov State Medical University.
29, Nahichevansky Lane, Rostov-on-Don, 344022
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Review
For citations:
Maevskaya MV, Bessonova EN, Geyvandova NI, Kitsenko EA, Korochanskaia NV, Morozov VG, Khoronko YV. The role of thrombocytopenia in the clinical management of patients with liver cirrhosis: opinion of experts in therapeutic and surgical hepatology. Meditsinskiy sovet = Medical Council. 2022;(23):142-147. (In Russ.) https://doi.org/10.21518/2079-701X-2022-16-23-2