Cognitive functional therapy and non-steroidal anti-inflammatory drugs in the treatment of low back pain
https://doi.org/10.21518/2079-701X-2022-16-23-78-85
Abstract
A multidisciplinary approach including drug and non-drug methods is recommended for the treatment of chronic low back pain (CLBP). Kinesiotherapy, psychological methods, and nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to be highly effective for CLBP. All of the listed methods contribute to significant relief and relief of pain, increase the patient’s social and physical activity, and improve the emotional state. Psychological methods help patients cope with catastrophizing pain, increase daily activities, and reduce the likelihood of disease recurrence. Results from clinical studies and systematic reviews demonstrate the effectiveness of psychological techniques such as cognitive behavioral therapy (CBT) and mindfulness therapy (mindfulness) in the treatment of CLBP. Cognitive Functional Therapy (CFT) is a promising new psychological method that was created on the basis of CPT. Clinical studies have been conducted confirming the efficacy of CFT in CLBP. CFT is aimed at regular therapeutic exercises, normalization of motor activity with avoidance of excessive physical and static exertion, avoidance of sedentary lifestyle and normalization of sleep, which is often disturbed in chronic back pain. In practice, patients with CLBP often have low adherence to increased physical activity during the day, to therapeutic exercises. In most cases, this is due to the fact that in the first days of increased physical activity there is an increase in pain. Patients mistakenly fear further progression of pain and disease. Prescribing NSAIDs usually results in pain reduction as early as the first days of administration, so patients with chronic musculoskeletal pain have an increased desire to engage in physical activity and therapeutic exercises. The choice of a particular NSAID medication is made individually, taking into account the co-morbidities and the risk of possible side effects. We discuss the use of nimesulide in CLBP.
About the Authors
O. E. ZinovyevaRussian Federation
Olga E. Zinovyeva - Dr. Sci. (Med.), Professor of the Department of Nervous Diseases and Neurosurgery, Sklifosovsky Institute of Clinical Medicine, Sechenov First Moscow State Medical University (Sechenov University).
8, Bldg. 2, Trubetskaya St., Moscow, 119991
A. A. Golovacheva
Russian Federation
Anzhelika A. Golovacheva - Resident, Department of Nervous Diseases and Neurosurgery, Sklifosovsky Institute of Clinical Medicine, Sechenov First Moscow State Medical University (Sechenov University).
8, Bldg. 2, Trubetskaya St., Moscow, 119991
References
1. Walker B.F. The prevalence of low back pain: a systematic review of the literature from 1966 to 1998. J Spinal Disord. 2000;13(3):205–217. https://doi.org/10.1097/00002517-200006000-00003.
2. Jordan K.P., Kadam U.T., Hayward R., Porcheret M., Young C., Croft P. Annual consultation prevalence of regional musculoskeletal problems in primary care: an observational study. BMC Musculoskelet Disord. 2010;11:144. https://doi.org/10.1186/1471-2474-11-144.
3. Parfenov V.A., Yakhno N.N., Davydov O.S., Kukushkin M.L., Churyukanov M.V., Golovacheva V.A. et al. Chronic nonspecific (musculoskeletal) low back pain. Guidelines of the Russian Society for the Study of Pain (RSSP). Neurology, Neuropsychiatry, Psychosomatics. 2019;11(2S):7–16. https://doi.org/10.14412/2074-2711-2019-2S-7-16.
4. Parfenov V.A., Yakhno N.N., Kukushkin M.L., Churyukanov M.V., Davydov O.S., Golovacheva V.A. et al. Acute nonspecific (musculoskeletal) low back pain Guidelines of the Russian Society for the Study of Pain (RSSP). Neurology, Neuropsychiatry, Psychosomatics. 2018;10(2):4–11. https://doi.org/10.14412/2074-2711-2018-2-4-11.
5. Airaksinen O., Brox J.I., Cedraschi C., Hildebrandt J., Klaber-Moffett J., Kovacs F. et al. Chapter 4. European guidelines for the management of chronic nonspecific low back pain. Eur Spine J. 2006;15(Suppl. 2):S192–300. https://doi.org/10.1007/s00586-006-1072-1.
6. Kamper S.J., Apeldoorn A.T., Chiarotto A., Smeets R.J., Ostelo R.W., Guzman J., van Tulder M.W. Multidisciplinary biopsychosocial rehabilitation for chronic low back pain: Cochrane systematic review and meta-analysis. BMJ. 2015;350:h444. https://doi.org/10.1136/bmj.h444.
7. Golovacheva V.A., Golovacheva A.A. B vitamins and nonsteroidal anti-inflammatory drugs: the efficacy of the combination for nonspecific back pain. Neurology, Neuropsychiatry, Psychosomatics. 2020;12(5):117–122 (In Russ.) https://doi.org/10.14412/2074-2711-2020-5-117-122.
8. Golovacheva V.A., Golovacheva A.A., Zinovyeva O.E., Golubev V.L. Tolperisone in the treatment of acute and chronic nonspecific back pain. Neurology, Neuropsychiatry, Psychosomatics. 2020;12(4):137–142. (In Russ.) https://doi.org/10.14412/2074-2711-2020-4-137-142.
9. Kukushkin M.L., Brylev L.V., Laskov V.B., Makarov N.S., Pizova N.V., Sokov E.L. et al. Results of a randomized double blind parallel study on the efficacy and safety of tolpersione in patients with acute nonspecific low back pain. Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova. 2017;117(11):69–78. (In Russ.) https://doi.org/10.17116/jnevro201711711169-78.
10. Calderon-Ospina C.A., Nava-Mesa M.O., Arbeláez Ariza C.E. Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis. Pain Med. 2020;21(4):766–781. https://doi.org/10.1093/pm/pnz216.
11. Mibielli M.A., Geller M., Cohen J.C., Goldberg S.G., Cohen M.T., Nunes C.P. et al. Diclofenac plus B vitamins versus diclofenac monotherapy in lumbago: the DOLOR study. Curr Med Res Opin. 2009;25(11):2589–2599. https://doi.org/10.3111/13696990903246911.
12. Vitoula K., Venneri A., Varrassi G., Paladini A., Sykioti P., Adewusi J., Zis P. Behavioral Therapy Approaches for the Management of Low Back Pain: An Up-To-Date Systematic Review. Pain Ther. 2018;7(1):1–12. https://doi.org/10.1007/s40122-018-0099-4.
13. Golovacheva V.A., Golovacheva A.A., Fateeva T.G. Psychological methods in the treatment of chronic nonspecific low back pain. Neurology, Neuropsychiatry, Psychosomatics. 2019;11(2S):25–32. (In Russ.) https://doi.org/10.14412/2074-2711-2019-2S-25-32.
14. Golovacheva A.A., Golovacheva V.A., Parfenov V.A. Kinesiotherapy and non-steroidal anti-inflammatory drugs for nonspecific lumbago. Neurology, Neuropsychiatry, Psychosomatics. 2022;14(1):89–96. (In Russ.) https://doi.org/10.14412/2074-2711-2022-1-89-96.
15. Oliveira C.B., Maher C.G., Pinto R.Z., Traeger A.C., Lin C.C., Chenot J.F. et al. Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview. Eur Spine J. 2018;27(11):2791–2803. https://doi.org/10.1007/s00586-018-5673-2.
16. Vibe Fersum K., Smith A., Kvåle A., Skouen J.S., O’Sullivan P. Cognitive functional therapy in patients with non-specific chronic low back pain-a randomized controlled trial 3-year follow-up. Eur J Pain. 2019;23(8):1416–1424. https://doi.org/10.1002/ejp.1399.
17. Cutforth G., Peter A., Taenzer P. The Alberta Health Technology Assessment (HTA) Ambassador Program: The Development of a Contextually Relevant, Multidisciplinary Clinical Practice Guideline for Non-specific Low Back Pain: A Review. Physiother Can. 2011;63(3):278–286. https://doi.org/10.3138/ptc.2009-39P.
18. Golovacheva V.A., Golovacheva A.A., Fateyeva T.G. Clinical principles for the diagnosis and treatment of musculoskeletal (non-specific) lower back pain. Neurology, Neuropsychiatry, Psychosomatics. 2021;13(3):107–112. (In Russ.) https://doi.org/10.14412/2074-2711-2021-3-107-112.
19. Golovacheva V.A., Golovacheva A.A. B vitamins and nonsteroidal anti-inflammatory drugs: the efficacy of the combination for nonspecific back pain. Neurology, Neuropsychiatry, Psychosomatics. 2020;12(5):117–122. (In Russ.) https://doi.org/10.14412/2074-2711-2020-5-117-122.
20. Hong J.Y., Song K.S., Cho J.H., Lee J.H. An Updated Overview of Low Back Pain Management in Primary Care. Asian Spine J. 2017;11(4):653–660. https://doi.org/10.4184/asj.2017.11.4.653.
21. Letzel J., Angst F., Weigl M.B. Multidisciplinary biopsychosocial rehabilitation in chronic neck pain: a naturalistic prospective cohort study with intraindividual control of effects and 12-month follow-up. Eur J Phys Rehabil Med. 2019;55(5):665–675. https://doi.org/10.23736/S1973-9087.18.05348-0.
22. Parfenov V.A., Golovacheva V.A. Chronic pain and its treatment in neurology. Moscow: GEOTAR-Media; 2018. 288 p. (In Russ.)
23. Parfenov V.A., Isaikin A.I. Pain in the lower back: myths and reality. Moscow: IMA-PRESS; 2016. 104 p. (In Russ.)
24. O’Keeffe M., O’Sullivan P., Purtill H., Bargary N., O’Sullivan K. Cognitive functional therapy compared with a group-based exercise and education intervention for chronic low back pain: a multicentre randomised controlled trial (RCT). Br J Sports Med. 2020;54(13):782–789. https://doi.org/10.1136/bjsports-2019-100780.
25. Conway D., Ladlow P., Ferreira J., Mani-Babu S., Bennett A.N. Cognitive functional therapy (CFT)-based rehabilitation improves clinical outcomes in UK military personnel with persistent low back pain. BMJ Mil Health. 2020;166(5):336–341. https://doi.org/10.1136/jramc-2018-001136.
26. Parfenov V.A. Management of patients with chronic nonspecific lumbar pain. Meditsinskiy Sovet. 2019;(1):40–45. (In Russ.) https://doi.org/10.21518/2079-701X-2019-1-40-45.
27. Karateev A.E. Nonsteroidal anti-inflammatory drugs in present-day clinical practice: pro more than con. Modern Rheumatology Journal. 2008;2(1):70–78. (In Russ.) https://doi.org/10.14412/1996-7012-2008-463.
28. Nasonov E.L., Yakhno N.N., Karateev A.E., Alekseeva L.I., Barinov A.N., Barulin A.E. et al. General principles of treatment for musculoskeletal pain: interdisciplinary consensus. Rheumatology Science and Practice. 2016;54(3):247–265. (In Russ.) Available at: https://rsp.mediar-press.net/rsp/article/view/2206.
29. Laporte J.R., Ibáñez L., Vidal X., Vendrell L., Leone R. Upper gastrointestinal bleeding associated with the use of NSAIDs: newer versus older agents. Drug Saf. 2004;27(6):411–420. https://doi.org/10.2165/00002018-200427060-00005.
30. García Rodríguez L.A., Barreales Tolosa L. Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population. Gastroenterology. 2007;132(2):498–506. https://doi.org/10.1053/j.gastro.2006.12.007.
31. Xu S., Rouzer C.A., Marnett L.J. Oxicams, a class of nonsteroidal anti-inflammatory drugs and beyond. IUBMB Life. 2014;66(12):803–811. https://doi.org/10.1002/iub.1334.
32. Karateev A.E., Nasonov E.L., Ivashkin V.T., Martynov A.I., Yakhno N.N., Arutyunov G.P. et al. Rational use of nonsteroidal anti-inflammatory drugs. Clinical guidelines. Rheumatology Science and Practice. 2018;56:1–29. (In Russ.) Available at: https://rsp.mediar-press.net/rsp/article/view/2536/1691.
33. Bjarnason I. Therapeutic Roles of Selective COX-2 Inhibitors: Edited by J R Vane, R M Botting. William Harvey Press, 2001. ISBN-0 9534039-1-2. Gut. 2003;52(5):773. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1773661/.
34. Bree F., Nguyen P., Urien S., Albengres E., Macciocchi A., Tillement J.P. Nimesulide binding to components within blood. Drugs. 1993;46(Suppl. 1): 83–90. https://doi.org/10.2165/00003495-199300461-00016.
35. Bunczak-Reeh M.A., Hargreaves K.M. Effect of inflammation on the delivery of drugs to dental pulp. J Endod. 1998;24(12):822–825. https://doi.org/10.1016/S0099-2399(98)80010-1.
36. Castellsague J., Riera-Guardia N., Calingaert B., Varas-Lorenzo C., Fourrier-Reglat A., Nicotra F. et al. Individual NSAIDs and upper gastrointestinal complications: a systematic review and meta-analysis of observational studies (the SOS project). Drug Saf. 2012;35(12):1127–1146. https://doi.org/10.2165/11633470-000000000-00000.
37. Conforti A., Leone R., Moretti U., Mozzo F., Velo G. Adverse drug reactions related to the use of NSAIDs with a focus on nimesulide: results of spontaneous reporting from a Northern Italian area. Drug Saf. 2001;24(14):1081–1090. https://doi.org/10.2165/00002018-200124140-00006.
38. Karateyev A.E., Karateyev D.E., Nasonov E.L. Gastroduodenal safety of Nimesulid (Nimesil, Berlin Chemie) in rheumatic patients with history of ulcer. Rheumatology Science and Practice. 2003;41(1):36–39. (In Russ.) Available at: https://rsp.mediar-press.net/rsp/article/view/1050/723.
39. Traversa G., Bianchi C., Da Cas R., Abraha I., Menniti-Ippolito F., Venegoni M. Cohort study of hepatotoxicity associated with nimesulide and other non-steroidal anti-inflammatory drugs. BMJ. 2003;327(7405):18–22. https://doi.org/10.1136/bmj.327.7405.18.
40. Kress H.G., Baltov A., Basiński A., Berghea F., Castellsague J., Codreanu C. et al. Acute pain: a multifaceted challenge – the role of nimesulide. Curr Med Res Opin. 2016;32(1):23–36. https://doi.org/10.1185/03007995.2015.1100986.
41. Helin-Salmivaara A., Virtanen A., Vesalainen R., Grönroos J.M., Klaukka T., Idänpään-Heikkilä J.E., Huupponen R. NSAID use and the risk of hospitalization for first myocardial infarction in the general population: a nation-wide case-control study from Finland. Eur Heart J. 2006;27(14):1657–1663. https://doi.org/10.1093/eurheartj/ehl053.
42. Barskova V.G., Nasonova V.A., Tsapina T.N., Karateev A.E., Yakunina I.A., Eliseev M.S. Efficacy and safety of using Nimesil in gouty arthritis. Clinical Medicine (Russian Journal). 2004;82(12):49–54. (In Russ.) Available at: https://www.elibrary.ru/item.asp?id=17088793.
43. Aw T.J., Haas S.J., Liew D., Krum H. Meta-analysis of cyclooxygen-ase-2 inhibitors and their effects on blood pressure. Arch Intern Med. 2005;165(5):490–496. https://doi.org/10.1001/archinte.165.5.IOI50013.
44. Egorov I.V., Tsurko V.V. Features of treatment for articular syndrome in elderly patients with arterial hypertension specific. Modern Rheumatology Journal. 2008;2(4):52–54. (In Russ.) https://doi.org/10.14412/1996-7012-2008-508.
45. Alexeeva L.I., Karateev A.E., Popkova T.V., Novikova D.S., Sharapova E.N., Markelova E.P., Nasonov E.L. Efficacy and safety of nimesulide long term administration in patients with osteoarthritis: results of 12-months open controlled study DINAMO (long term administration of nimesulide in osteoarthritis multifactor assessment). Rheumatology Science and Practice. 2009;47(4):64–72. (In Russ.) https://doi.org/10.14412/1995-4484-2009-1152.
46. Pohjolainen T., Jekunen A., Autio L., Vuorela H. Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen. Spine (Phila Pa 1976). 2000;25(12):1579–1585. https://doi.org/10.1097/00007632-200006150-00019.
47. Karateev A.E., Lila A.M., Churyukanov M.V., Skorobogatykh K.V., Amelin A.V., Zakharov D.V. et al. Evaluation of the effectiveness of a nonsteroidal anti-inflammatory drug (NSAID) selection algorithm based on the analysis of risk factors for drug-induced complications in real clinical practice: the results of the All-Russian principle project (applicat). Rheumatology Science and Practice. 2017;55(5):485–492. (In Russ.) https://doi.org/10.14412/1995-4484-2017-485-492.
48. Shikhkerimov R.K. The use of nimesulide in the treatment of acute low back pain. Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova. 2016;116(5):28–32. (In Russ.) https://doi.org/10.17116/jnevro20161165128-32.
49. Binning A. Nimesulide in the treatment of postoperative pain: a double-blind, comparative study in patients undergoing arthroscopic knee surgery. Clin J Pain. 2007;23(7):565–570. https://doi.org/10.1097/AJP.0b013e3180e00dff.
Review
For citations:
Zinovyeva OE, Golovacheva AA. Cognitive functional therapy and non-steroidal anti-inflammatory drugs in the treatment of low back pain. Meditsinskiy sovet = Medical Council. 2022;(23):78-85. (In Russ.) https://doi.org/10.21518/2079-701X-2022-16-23-78-85