Intestinal microflora as a factor of human health
https://doi.org/10.21518/2079-701X-2013-1-1-30-33
Abstract
The article is an overview of contemporary global studies summarizing the results of research of composition of intestinal microflora and its effect on human health. Gene sequencing of 16S ribosomal RNA amplified bacterial nucleic acids was applied to define most common European enterotypes and highlight the factors that influence the formation of enterotype. The possible relationship between intestinal microbiota and obesity is highlighted.
About the Authors
E. M. Bulatova
ГОУ ВПО «Санкт-Петербургская государственная педиатрическая медицинская академия Росздрава», С.-Петербург
Russian Federation
Russian Federation
N. M. Bogdanova
ГОУ ВПО «Санкт-Петербургская государственная педиатрическая медицинская академия Росздрава», С.-Петербург
Russian Federation
Russian Federation
References
1. Мечников И.И. Этюды о природе человека. М.: изд-во Академии наук СССР, 1961.
2. Shui W., Gilmore S.A., Sheu L., Liu J., Keasling J.D., Bertozzi C.R. Quantitative Proteomic Profiling of Host–Pathogen nteractions: The Macrophage Response to Mycobacterium tuberculosis Lipids. J Proteome Res 2009; 8(1): 282–289.
3. Guarino A., Wudy A., Basile F., Ruberto E., Buccigrossi V. Composition and roles of intestinal microbiota in children. J Matern Fetal Neonatal Med. 2012 Apr; 25 Suppl 1: 63–6.
4. Andresen V., Camilleri M. Irritable bowel syndrome: recent and novel therapeutic approaches Drugs. – 2006; 66(8): 1073–88.
5. Kassinen A., Krogius-Kurikka L., Mäkivuokko H., Rinttilä T., Paulin L., Corander J., Malinen E., Apajalahti J., Palva A. The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects // Gastroenterology – 2007; 133(1): 24–33.
6. Sartor R.B. Microbial influences in inflammatory bowel diseases // Gastroenterology. – 2008; 134 (2): 577–94.
7. Maslowski K.M., Mackay C.R. Diet, gut microbiota and immune responses. Nat Immunol. 2011; 12: 5–9.
8. Rachmilewitz D., Katakura K., Karmeli F., Hayashi T., Reinus C., Rudensky B., Akira S., Takeda K., Lee J., Takabayashi K., Raz E. Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis // Gastroenterology. – 2004; 126 (2): 520–8.
9. Reinhardt C., Reigstad C.S., Bäckhed F. Intestinal microbiota during infancy and its implications for obesity // J Pediatr Gastroenterol Nutr. – 2009; 48(3): 249–56.
10. Grunland M., Guimonde M., Laitinen K. Maternal breast-milk and intestinal bifidobacteria guide the compositional development of the
11. Bifidobacterium microbiota in infants at risk of allergic disease // Clin. and Experimental Allergy – 2007; 111: 1–9.
Review
For citations:
Bulatova EM, Bogdanova NM. Intestinal microflora as a factor of human health. Meditsinskiy sovet = Medical Council. 2013;(1-1):30-33. (In Russ.) https://doi.org/10.21518/2079-701X-2013-1-1-30-33
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