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Respiratory support and oxygen therapy at home: Clinical results of the prospective observatory study

https://doi.org/10.21518/ms2024-419

Abstract

Introduction. Respiratory diseases are number one in the structure of general morbidity of the population of the Russian Federation. The main complication of respiratory diseases is respiratory failure, which may be treated with long-term oxygen therapy (LTOT) and respiratory support (RS): non-invasive mechanical lung ventilation (NIV) and invasive mechanical lung ventilation (IV). International medical experience indicates a widespread enough implementation of respiratory support and oxygen therapy at home (RS and OT at home) for patients including whose requiring palliative medical care.

Aim. The purpose of the study was to evaluate the clinical results of implementation of respiratory support and oxygen therapy at home.

Materials and methods. The study included 98 patients with chronic respiratory failure (CRF). All patients used RS and OT at home according to the Study Protocol. All patients were divided into 3 groups: LTOT - 47 patients, NIV in combination or with-out LTOT - 43 patients, IV in combination or without LTOT - 8 patients. The estimated parameters of the patients' condition were measured at the initiating visit and three subsequent control sessions. The planned duration of the Study was 9 months.

Results. During the Study, a statistically significant decrease in the severity of symptoms of respiratory failure was noted (CAT and mMRC scales) as well as an improvement in the quality of life and the general condition of the patient (SF-36 questionnaire and Karnovsky scale). During the study, 38 patients required hospitalization: in 8 cases hospitalization was associated with an exacerbation of CRF. The number of successful outcomes was 87 cases.

Conclusion. The Study showed that RS and OT at home is an effective and safe medical technology for patients with CFR, which reduces the manifestation of symptoms, improves the quality of life, reduces the number of hospitalizations associated with exacerbation of respiratory failure, reduces mortality, and demonstrates the effectiveness of using a modern respiratory equipment at home, as well as telemedicine technologies.

About the Authors

S. N. Avdeev
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Sergey N. Avdeev - Acad RAS, Dr. Sci. (Med.), Professor, Chief Freelance Specialist in Pulmonology of the Ministry of Health of the Russian Federation, Head of the Department of Pulmonology, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991


D. N. Nevzorova
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Diana V. Nevzorova - Cand. Sci. (Med.), Associate Professor, Chief Freelance Specialist in Palliative Care at the Ministry of Health of the Russian Federation, Director of the Federal Scientific and Practical Centre for Palliative Medical Care, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991


G. E. Ivanova
Pirogov Russian National Research Medical University
Russian Federation

Galina E. Ivanova - Dr. Sci. (Med.), Professor, Chief Freelance Specialist in Medical Rehabilitation of the Ministry of Health of the Russian Federation, Head of the Department for Medical Rehabilitation of the Faculty for Additional Professional Education, Pirogov Russian National Research Medical University.

1, Ostrovityanov St., Moscow, 117997


G. S. Lebedev
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Georgy S. Lebedev - Dr. Sci. (Eng.) , Associate Professor, Director of the Institute for Digital Medicine, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991


N. A. Suponeva
Scientific Centre for Neurology
Russian Federation

Natalia A. Suponeva - Corr Member of RAS, Dr. Sci. (Med.), Professor, Director of the Institute for Neurorehabilitation and Recovery Medicine, Scientific Centre for Neurology.

80, Volokolamskoe Shosse, Moscow, 125367


M. V. Avxentyeva
Sechenov First Moscow State Medical University (Sechenov University); Centre for Expertise and Quality Control of Healthcare
Russian Federation

Maria V. Avxentyeva - Dr. Sci. (Med.), Professor of the Higher School for Healthcare Management, Sechenov First Moscow State Medical University (Sechenov University); Advisor to Director, Centre for Expertise and Quality Control of Healthcare.

8, Bldg. 2, Trubetskaya St., Moscow, 119991; 10, Bldg. 5, Khokhlovskiy Lane, Moscow, 109028


R. I. Shaburov
Central Clinical Hospital “RZhD-Medicine named after N.A. Semashko”
Russian Federation

Rafik I. Shaburov - Cand. Sci. (Med.), Chief Doctor, Central Clinical Hospital “RZhD-Medicine named after N.A. Semashko”.

2, Bldg. 1, Budayskaya St., Moscow, 129128


E. S. Larin
Hospital for the Veterans of War No. 3; Scientific and Research Institute for the Organization of Healthcare and Medical Management
Russian Federation

Egor S. Larin - Deputy for Anesthesiology and Intensive Care, Hospital for the Veterans of War No. 3; Head of Or-ganizational and Methodological Department for Anesthesiology and Resuscitation, Scientific and Research Institute for the Organization of Healthcare and Medical Management.

4, Startovaya St., Moscow, 129336; 9, Sharikopodshipnikovskaya St., Moscow,115088


A. N. Komarov
National Center for the Development of the Technologies for the Social Support and Rehabilitation “Doverie”
Russian Federation

Alexander N. Komarov - Cand. Sci. (Med.), Professor, General Director, National Center for the Development of the Technologies for the Social Support and Rehabilitation “Doverie”.

40g, Altufievskoe Shosse, Moscow, 127051


G. N. Levitsky
Charity Fund for Assistance of ALS Patients named after N.I. Levitskaya
Russian Federation

Gleb N. Levitsky - Cand. Sci. (Med.), Director, СЬ^^У Fund for Assistance of ALS Patients named after N.I. Levitskaya.

35, Bldg. 9, Nizhnyaya Krasnoselskaya St., Moscow, 105066


S. E. Nazarov
Incomed LLC
Russian Federation

Sergey E. Nazarov - General Director, Incomed LLC.

17b, Butlerov St., Moscow, 117342


Z. M. Merzhoeva
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Zamira M. Merzhoeva - Cand. Sci. (Med.), Assistant of the Department of Pulmonology, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991


N. A. Karchevskaya
Scientific and Research Institute of the Emergency Healthcare named after N.V. Sklifosovskiy
Russian Federation

Natalia A. Karchevskaya - Researcher of the Department of the Thoracic-abdominal Surgery, Scientific and Research Institute of the Emergency Healthcare named after N.V. Sklifosovskiy.

3, Bolshaya Sukharevskaya Square, Moscow, 129090


A. V. Morev
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Andrey V. Morev - Head of the Department of Palliative Medical Care of the Federal Scientific and Practical Centre for Palliative Medical Care, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991


V. A. Movsisyan
Hospital for the Veterans of War No. 3
Russian Federation

Vagram A. Movsisyan - Head of the Department of Early Medical Rehabilitation, Hospital for the Veterans of War No. 3.

4, Startovaya St., Moscow, 129336


A. S. Vasilyeva
Station for Emergency Medical Care named after A.S. Puchkov
Russian Federation

Anastasia S. Vasilyeva - Anesthesiologist and Intensive Care Doctor, Station for Emergency Medical Care named after A.S. Puchkov.

1, Bldg. 3, 1st Koptelskiy Lane, Moscow, 129090


Kh. S. Delmaeva
Sechenov First Moscow State Medical University (Sechenov University); City Clinical Hospital named after S.S. Yudin
Russian Federation

Kheda S. Delmaeva - Postgraduate Student of the N.V. Sklifosovsky Institute of Clinical Medicine, Sechenov First Moscow State Medical University (Sechenov University); Physician, City Clinical Hospital named after S.S. Yudin.

8, Bldg. 2, Trubetskaya St., Moscow, 119991; 4, Kolomensky Lane, Moscow, 115446


A. O. Bykov
Pirogov Russian National Research Medical University; Moscow Multidisciplinary Clinical Centre “Kommunarka”
Russian Federation

Andrey O. Bykov - Assistant of the Department of Anesthesiology and Intensive Care of the Faculty for Additional Professional Education, Pirogov Russian National Research Medical University; Anesthesiologist and Intensive Care Doctor, Moscow Multidisciplinary Clinical Centre “Kommunarka”.

1, Ostrovityanov St., Moscow, 117997; 8, Sosenskiy Stan, Settlement Kommunarka, Moscow, 108814


B. E. Pervozvanskiy
Centre for the Development of Outpatient Medical Technologies and Home-Based Medical Care
Russian Federation

Boris Е. Pervozvanskiy - Advisor to the President, Centre for the Development of Outpatient Medical Technologies and Home-Based Medical Care.

3b, Ryazhanskiy Лұе., Moscow, 109052


V. V. Tkachenko
Centre for the Development of Outpatient Medical Technologies and Home-Based Medical Care
Russian Federation

Vadim V. Tkachenko - Master of Public Health, President, Centre for the Development of Outpatient Medical Technologies and Home-Based Medical Care.

3b, Ryazhanskiy Лұе., Moscow, 109052


K. A. Krokhin
Sechenov First Moscow State Medical University (Sechenov University); Centre for the Development of Outpatient Medical Technologies and Home-Based Medical Care
Russian Federation

Kirill A. Krokhin - Master of Public Health, Postgraduate Student at the Institute of Leadership and Health Management, Sechenov First Moscow State Medical University (Sechenov University); Vice-President, Centre for the Development of Outpatient Medical Technologies and Home-Based Medical Care.

8, Bldg. 2, Trubetskaya St., Moscow, 119991; 3b, Ryazhanskiy Ave., Moscow, 109052


G. S. Nuralieva
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Galiya S. Nuralieva - Cand. Sci. (Med.), Associate Professor at the Department of Pulmonology, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991


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Review

For citations:

Avdeev SN, Nevzorova DN, Ivanova GE, Lebedev GS, Suponeva NA, Avxentyeva MV, Shaburov RI, Larin ES, Komarov AN, Levitsky GN, Nazarov SE, Merzhoeva ZM, Karchevskaya NA, Morev AV, Movsisyan VA, Vasilyeva AS, Delmaeva KS, Bykov AO, Pervozvanskiy BE, Tkachenko VV, Krokhin KA, Nuralieva GS. Respiratory support and oxygen therapy at home: Clinical results of the prospective observatory study. Meditsinskiy sovet = Medical Council. 2024;(20):70-81. (In Russ.) https://doi.org/10.21518/ms2024-419

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