Current approach to the management of adnexal torsion
https://doi.org/10.21518/ms2024-542
Abstract
Introduction. In the structure of urgent gynecological practice, ovarian torsion ranks fifth, which is usually diagnosed in women of reproductive age. To date, there is no single standard for assessing the viability of the ovary and choosing a conservative or radical operation for patients with ovarian torsion, in this regard, there is a need to search for potential predictors that determine the validity of the choice of the volume of surgical intervention.
Aim. To optimize management tactics for patients with uterine torsion.
Materials and methods. In a retrospective study, an analysis of 55 case histories of patients admitted to a gynecological hospital with a diagnosis of ovarian torsion was carried out. Depending on the organ-preserving and organ-removing surgical treatment, the patients were divided into two groups. The analysis of the studied indicators was carried out using correlation, regression, factor and ROC analysis.
Results. The results of the study demonstrated that only a visual assessment of the state of the ovarian torsion to unjustified organ-removing interventions in 57.1% of patients. Based on correlation, factor, regression and ROC analysis, diagnostically significant predictors determining the volume of surgical intervention were determined.
Conclusions. Based on the retrospective analysis, an algorithm for managing patients with ovarian torsion was developed: at stages A and B according to the clinical classification of ovarian torsion damage, regardless of the studied criteria, organpreserving treatment – detorsion must be performed; at stage C, special attention is paid to D-dimer values: at D-dimer <1450 ng/ml – detorsion, and only at D-dimer >1490 ng/ml – organ-preserving surgery.
About the Authors
J. E. DobrokhotovaRussian Federation
Julia E. Dobrokhotova - Dr. Sci. (Med.), Professor, Honoured Doctor of the Russian Federation, Head of the Department of Obstetrics and Gynecology.
1, Ostrovityanov St., Moscow, 117997
A. A. Shchegolev
Russian Federation
Aleksandr A. Shchegolev - Dr. Sci. (Med.), Professor, Head of the Department of Hospital Surgery of the Pediatric Faculty.
1, Ostrovityanov St., Moscow, 117997
A. E. Markarov
Russian Federation
Arnold E. Markarov - Cand. Sci. (Med.), Chief Medical Officer.
1, Fortunatovskaya St., Moscow, 105187
T. S. Kotomina
Russian Federation
Tatiana S. Kotomina - Cand. Sci. (Med.), Deputy Chief Physician for Obstetrics and Gynecology Care.
1, Fortunatovskaya St., Moscow, 105187
S. A. Khlynova
Russian Federation
Svetlana A. Khlynova - Cand. Sci. (Med.), Associate Professor of the Department of Obstetrics and Gynecology, Faculty of General Medicine, Pirogov Russian NRMU; Obstetrician-Gynecologist, Inozemtsev City Clinical Hospital;
1, Ostrovityanov St., Moscow, 117997; 1, Fortunatovskaya St., Moscow, 105187
V. I. Dimitrova
Russian Federation
Valentina I. Dimitrova, Cand. Sci. (Med.), Head of the gynecological department.
1, Fortunatovskaya St., Moscow, 105187
E. A. Markova
Russian Federation
Eleonora A. Markova - Cand. Sci. (Med.), Associate Professor of the Department of Obstetrics and Gynecology, Faculty of General Medicine, Pirogov Russian NRMU; Obstetrician-Gynecologist, Inozemtsev CCH.
1, Ostrovityanov St., Moscow, 117997; 1, Fortunatovskaya St., Moscow, 105187
O. A. Slyusareva
Russian Federation
Olga A. Slyusareva - Cand. Sci. (Med.), Obstetrician-Gynecologist.
1, Fortunatovskaya St., Moscow, 105187
References
1. Bridwell RE, Koyfman A, Long B. High risk and low prevalence diseases: Ovarian torsion. Am J Emerg Med. 2022;56:145–150. https://doi.org/10.1016/j.ajem.2022.03.046.
2. Segars JH, Al-Hendy A. Uterine Leiomyoma: New Perspectives on an Old Disease. Semin Reprod Med. 2017;35(6):471–472. https://doi.org/10.1055/s-0037-1606569.
3. Artymuk NV, Lamonova SS, Chernova OO. Benign ovarian masses in adolescent girls: classification, clinical features, tactics. Pediatric and Adolescent Reproductive Health. 2021;17(4):28–38. (In Russ.) https://doi.org/10.33029/1816-2134-2021-17-4-28-38.
4. Novoa M, Friedman J, Mayrink M. Ovarian torsion: can we save the ovary? Arch Gynecol Obstet. 2021;304(1):191–195. https://doi.org/10.1007/s00404-021-06008-8.
5. Shwyiat R, Taso OA, Al-Edwan F, Khreisat B, Al-Dubees A. Retrospective analysis of patients with surgically proven ovarian torsion, our experience. J Family Med Prim Care. 2023;12(4):637–643. https://doi.org/10.4103/jfmpc.jfmpc_1450_22.
6. Tielli A, Scala A, Alison M, Vo Chieu VD, Farkas N, Titomanlio L, Lenglart L. Ovarian torsion: diagnosis, surgery, and fertility preservation in the pediatric population. Eur J Pediatr. 2022;181(4):1405–1411. https://doi.org/10.1007/s00431-021-04352-0.
7. Tabbara F, Hariri M, Hitti E. Ovarian torsion: A retrospective case series at a tertiary care center emergency department. PLoS ONE. 2024;19(3):e0297690. https://doi.org/10.1371/journal.pone.0297690.
8. Verma M, Bhuria V, Chauhan M, Nanda S, Dahiya P, Singhal SR. Adnexal Torsion: A Retrospective Analysis From a Tertiary Care Teaching Hospital in Northern India. Cureus. 2021;13(9):e17792. https://doi.org/10.7759/cureus.17792.
9. Buonacera A, Stancanelli B, Colaci M, Malatino L. Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases. Int J Mol Sci. 2022;23(7):3636. https://doi.org/10.3390/ ijms23073636.
10. Chen S, Gao Z, Qian Y, Chen Q. Key clinical predictors in the diagnosis of ovarian torsion in children. J Pediatr. 2024;100(4):399–405. https://doi.org/10.1016/j.jped.2024.01.006.
11. Tsai J, Lai JY, Lin YH, Tsai MH, Yeh PJ, Chen CL, Chang YJ. Characteristics and Risk Factors for Ischemic Ovary Torsion in Children. Children. 2022;9(2):206. https://doi.org/10.3390/children9020206.
12. Zeb A, Khurshid S, Bano S, Rasheed U, Zammurrad S, Khan MS, Aziz W, Tahir S. The Role of the Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio as Markers of Disease Activity in Ankylosing Spondylitis. Cureus. 2019;11(10):e6025. https://doi.org/10.7759/cureus.6025.
13. Agha Majidi M, Arab M, Ghodssi-Ghassemabadi R, Nouri B, Ghavami B, Sheibani K. Torsion among Women with Acute Lower Abdominal Pain: A Retrospective Cross-Sectional Study. Med J Islam Repub Iran. 2022;36:147. https://doi.org/10.47176/mjiri.36.147.
14. Moro F, Bolomini G, Sibal M, Vijayaraghavan SB, Venkatesh P, Nardelli F et al. Imaging in gynecological disease (20): clinical and ultrasound characteristics of adnexal torsion. Ultrasound Obstet Gynecol. 2020;56(6):934–943. https://doi.org/10.1002/uog.21981.
15. Pillot R, Hossu G, Cherifi A, Guillez K, Morel O, Beaumont M, Fijean AL, Bertholdt C. Contribution of contrast-enhanced ultrasound in the diagnosis of adnexal torsion (AGATA): protocol for a prospective comparative study. BMJ Open. 2023;13(8):e073301. https://doi.org/10.1136/bmjopen-2023-073301.
16. Wang Z, Zhang D, Zhang H, Guo X, Zheng J, Xie H. Characteristics of the patients with adnexal torsion and outcomes of different surgical procedures: A retrospective study. Medicine. 2019;98(5):e14321. https://doi.org/10.1097/MD.0000000000014321.
17. Panayotidis C, Nisolle M. Recent advances of laparoscopic approach in adnexal torsion of premenarcheal girl. Gynecol Surg. 2007;4:155–160. Available at: https://gynecolsurg.springeropen.com/articles/10.1007/s10397-007-0297-2.
18. Adams K, Ballard E, Amoako A, Khalil A, Baartz D, Chu K, Tanaka K. When is it too late? Ovarian preservation and duration of symptoms in ovarian torsion. J Obstet Gynaecol. 2022;42(4):675–679. https://doi.org/10.1080/01443615.2021.1929114.
19. Adnexal Torsion in Adolescents: ACOG Committee Opinion No. 783. Obstet Gynecol. 2019;134(2):e56–e63. https://doi.org/10.1097/AOG.0000000000003373.
20. Bardin R, Perl N, Mashiach R, Ram E, Orbach-Zinger S, Shmueli A et al. Prediction of Adnexal Torsion by Ultrasound in Women with Acute Abdominal Pain. Ultraschall Med. 2020;41(6):688–694. https://doi.org/10.1055/a-1014-2593.
21. Dawood MT, Naik M, Bharwani N, Sudderuddin SA, Rockall AG, Stewart VR. Adnexal Torsion: Review of Radiologic Appearances. RadioGraphics. 2021;41(2):609–624. https://doi.org/10.1148/rg.2021200118.
22. Ghulmiyyah L, Nassar A, Sassine D, Khoury S, Nassif J, Ramadan H et al. Accuracy of Pelvic Ultrasound in Diagnosing Adnexal Torsion. Radiol Res Pract. 2019;2019:1406291. https://doi.org/10.1155/2019/1406291.
23. Grunau GL, Harris A, Buckley J, Todd NJ. Diagnosis of Ovarian Torsion: Is It Time to Forget About Doppler? J Obstet Gynaecol Can. 2018;40(7):871–875. https://doi.org/10.1016/j.jogc.2017.09.013.
24. Topçu HO, İskender CT, Ceran U, Kaymak O, Timur H, Uygur D, Danışman N. Evaluation of the Diagnostic Accuracy of Serum D-Dimer Levels in Pregnant Women with Adnexal Torsion. Diagnostics. 2015;5(1):1–9. https://doi.org/10.3390/diagnostics5010001.
25. Kives S, Gascon S, Dubuc E, Van Eyk N. No. 341-diagnosis and management of adnexal torsion in children, adolescents, and adults. J Obstet Gynaecol Can. 2017;39(2):82–90. https://doi.org/10.1016/j.jogc.2016.10.001.
26. Zhu TW, Li XL. Ovarian Torsion: A Review of the Evidence. Obstet Gynecol Surv. 2024;79(8):484–492. https://doi.org/10.1097/OGX.0000000000001295.
27. Gu X, Yang M, Liu Y, Liu F, Liu D, Shi F. The ultrasonic whirlpool sign combined with plasma d-dimer level in adnexal torsion. Eur J Radiol. 2018;109:196–202. https://doi.org/10.1016/j.ejrad.2018.08.025.
28. Incebiyik A, Camuzcuoglu A, Hilal NG, Vural M, Camuzcuoglu H. Plasma D-dimer level in the diagnosis of adnexal torsion. J Matern Fetal Neonatal Med. 2015;28(9):1073–1076. https://doi.org/10.3109/14767058.2014.942636.
29. Naylor M, Doherty G, Draper H, Fletcher DM, Rigby A, Adedipe T, Guinn BA. Are There Non-Invasive Biomarker(s) That Would Facilitate the Detection of Ovarian Torsion? A Systematic Review and Meta-Analysis. Int J Mol Sci. 2024;25(21):11664. https://doi.org/10.3390/ijms252111664.
Review
For citations:
Dobrokhotova JE, Shchegolev AA, Markarov AE, Kotomina TS, Khlynova SA, Dimitrova VI, Markova EA, Slyusareva OA. Current approach to the management of adnexal torsion. Meditsinskiy sovet = Medical Council. 2024;(23):160-166. (In Russ.) https://doi.org/10.21518/ms2024-542