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The role of video capsule endoscopy in children with intestinal diseases

https://doi.org/10.21518/ms2025-363

Abstract

Introduction. In adult practice, video capsule endoscopy is used much more often than in children, which is most likely due to the age and emotional characteristics of children, as well as the limited availability of this endoscopic examination in pediatric practice.

Aim. To determine the diagnostic value of video capsule endoscopy in children with inflammatory diseases of the gastrointestinal tract.

Materials and methods. Between 2021 and 2025, 58 video capsule studies were conducted on 58 children, including 42 (72%) boys and 16 (28%) girls, with an average age of 9.7 years. Of the 58 children, 12 patients underwent video capsule endoscopy as part of a grant (agreement No. 1209-11/25) for inflammatory bowel diseases, with an average age of 12.25 years, including 7 (58%) boys and 5 (42%) girls. The children were divided into two groups: Group I consisted of 46 children who did not have any abnormalities in the small intestine or hidden sources of bleeding, while Group II included 12 children with inflammatory bowel diseases (as part of the grant). The youngest child underwent a video capsule study at the age of 3.

Results and discussions. When analyzing the results, patients were divided into groups according to the pathology identified. In 24% of cases, mucosal changes in the small intestine were detected in the form of hyperemia and edema; smoothness of folds, which corresponded to enteropathy, the second most common pathology was Crohn’s disease of the small intestine (22%). Peutz- Jeghers syndrome was detected in 9% of cases and in familial polyposis in 5% of cases; a rare pathology was detected in 3% of cases.

Conclusions. Video capsule endoscopy as a diagnostic method of the small intestine can be used in patients of child age from three years. The diagnostic value of video capsule endoscopy in detecting pathology of the small intestine is from 60% to 72%.

About the Authors

A. S. Koshurnikova
Children’s City Clinical Hospital named after Z.A. Bashlayeva of the Department of Healthcare of the city of Moscow
Россия

Anastasia S. Koshurnikova, Cand. Sci. (Med.), Head of the Endoscopy Department, Endoscopist, Moscow Doctor

28, Geroev Panfilovtsev St., Moscow, 125373



I. M. Osmanov
Children’s City Clinical Hospital named after Z.A. Bashlayeva of the Department of Healthcare of the city of Moscow
Россия

Ismail M. Osmanov, Dr. Sci. (Med.), Professor, Chief Pediatrician of the Moscow City Health Department, Chief Doctor

28, Geroev Panfilovtsev St., Moscow, 125373



E. V. Skorobogatova
Children’s City Clinical Hospital named after Z.A. Bashlayeva of the Department of Healthcare of the city of Moscow
Россия

Ekaterina V. Skorobogatova, Cand. Sci. (Med.), Head of the Gastroenterology Department, Gastroenterologist, Pediatrician

28, Geroev Panfilovtsev St., Moscow, 125373



Yu. A. Dmitrieva
Children’s City Clinical Hospital named after Z.A. Bashlayeva of the Department of Healthcare of the city of Moscow; Russian Medical Academy of Continuous Professional Education
Россия

Yulia A. Dmitrieva, Cand. Sci. (Med.), Head of the Gastrocenter, Gastroenterologist; ; Associate Professor, Department of Pediatrics named after G.N. Speransky

28, Geroev Panfilovtsev St., Moscow, 125373

2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993



I. N. Zakharova
Russian Medical Academy of Continuous Professional Education
Россия

Irina N. Zakharova, Dr. Sci. (Med.), Professor, Honored Doctor of the Russian Federation, Head of the Department of Pediatrics named after Academician G.N. Speransky

2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993



References

1. Koshurnikova AS, Zakharova IN, Osmanov IM, Skorobogatova EV, Epifanova EI. Modern endoscopic solutions in pediatric practice. Russian Bulletin of Perinatology and Pediatrics. 2023;68(1):5–10. (In Russ.) https://doi.org/10.21508/1027-4065-2023-68-1-5-10.

2. Fedorov ED, Ivanova EV, Plakhov RV, Buntseva OA. Wise up, is there an endpoint at the ends of the earth, and can the horizons be broaden?» Gastrointestinal endoscopy – 2014. Experimental and Clinical Gastroenterology. 2014;103(3):4–9. (In Russ.) Available at: https://elibrary.ru/szuuul.

3. Marakhovski KYU, Leskovskaya SV, Belyavskaya SV, Lyakh OM, Nikolaeva EV. Videocapsular endoscopy in intestinal diseases diagnostics in children in the Republic of Belarus. Meditsinskie Novosti. 2020;(3):21–25. (In Russ.) Available at: https://cyberleninka.ru/article/n/videokapsulnaya-endoskopiyav-diagnostike-kishechnyh-zabolevaniy-u-detey-v-respublike-belarus.

4. Shcherbakov P, Lokhmatov M. Videocapsular examinations in pediatrics. The history of development and use. Current Pediatrics. 2006;5(3):83–87. (In Russ.) Available at: https://vsp.spr-journal.ru/jour/article/view/743.

5. Akopova AO, Shcherbakov PL, Parfyonov AI, Mikheeva OM. Role of capsule endoscopy in diagnosing various disorders of small intestine. Doktor.Ru. 2015;(12):26–30. (In Russ.) Available at: https://journaldoctor.ru/catalog/gastroenterologiya/znachenie-kapsulnoy-endoskopiiv-diagnostike-razlichnykh-zabolevaniy-tonkoy-kishki/.

6. Tikhomirova EV, Ivanova EV, Budykina AV, Yudin OI, Mikhaleva LM, Fedorov ED. Results of diagnostics and treatment of small bowel bleeding. Endoscopic Surgery. 2023;29(5):5–14. (In Russ.) https://doi.org/10.17116/endoskop2023290515.

7. Кортиева АТ, Крушельницкий ВС, Габриэль СА, Дынько ВЮ, Гучетль АЯ. Сосудистая мальформация подвздошной кишки. Экспериментальная и клиническая гастроэнтерология. 2022;206(10):180–182. https://doi.org/10.31146/1682-8658-ecg-206-10-180-182. Kortieva AT, Krushelnitskiy VS, Gabriel SA, Dynko VYu, Guchetl AYa. Vascular malformation of ileum. Experimental and Clinical Gastroenterology. 2022;(10): 180–182. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-206-10-180-182.

8. Likutov AA, Vlasko TA, Veselov VV. The role of video capsule endoscopy in the diagnosis of gastrointestinal diseases: experience of the Department of Diagnostic and Operative Endoscopy. Ambulatornaya Khirurgiya. 2023;20(2):116–127. (In Russ.) https://doi.org/10.21518/akh2023-032.

9. Usacheva EV, Druk IV, Nadey EV, Usachev NA. Videocapsular endoscopy in the diagnosis of gastrointestinal diseases. Experimental and Clinical Gastroenterology. 2023;(3):61–68. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-211-3-61-68.

10. Shcherbakov PL. Capsule Endoscopy as Screening Method for Examining Gastrointestinal Tract in Outpatient Settings: Model of Reference Centers. Doktor.Ru. 2016;(10):23–28. (In Russ.) Available at: https://journaldoctor.ru/catalog/gastroenterologiya/kapsulnaya-endoskopiya/.

11. Zoumpos A, Ho NAH, Loeschhorn-Becker R, Schuppert F. Haemorrhagic small bowel melanoma metastasis:a clinical rarity. BMJ Case Rep. 2019;12(9):e230454. https://doi.org/10.1136/bcr-2019-230454.

12. Nouda S, Ota K, Higuchi K. Retrograde colon capsule endoscopy with the self-propelling capsule endoscope: The first human trial (with videos). Dig Endosc. 2018;30(1):117–118. https://doi.org/10.1111/den.12969.

13. Likutov AA, Veselov VV, Pritula NA, Nanaeva BA, Mtvralashvili DA. Possibilities of videocapsule endoscopy in the diagnosis of inflammatory bowel diseases. Endoscopic Surgery. 2017;(2):23–27. (In Russ.) https://doi.org/10.17116/endoskop201723223-27.

14. Lokhmatov MM, Budkina TN, Oldakovsky VI, Dyakonova EY, Potapov AS. First tries of using innovational capso vision capsule endoscopy system in treating children. Pediatric Pharmacology. 2016;13(6):587–591. (In Russ.) https://doi.org/10.15690/pf.v13i6.1673.

15. Koshurnikova AS, Zakharova IN, Osmanov IM. Endoscopic technologies in pediatric practice. MedVedomosti. 2023. (In Russ.) Available at: https://www.medvedomosti.media/pediatry/articles/ endoskopicheskie-tekhnologii-v-pediatricheskoy-praktike/.

16. Sadovnikova IV, Saralov SN, Sayfullin AP, Baranova SS. Diagnostic significance of videocapular endoscopy in childrens crown disease. Medicine: Theory and Practice. 2019;3(3 Suppl.)135–139. (In Russ.) Available at: https://ojs3.gpmu.org/index.php/med-theory-and-practice/article/view/359.

17. Kirakosyan EV, Lokhmatov MM, Dyakonova EY. High-tech diagnostic methods and enteroscopic treatment of children with Peutz-Jeghers syndrome. Russian Pediatric Journal. 2019;22(1):17–22. Available at: https://cyberleninka.ru/article/n/vysokotehnologichnaya-diagnostika-i-enteroskopicheskoelechenie-detey-s-sindromom-peyttsa-egersa.

18. Yamamoto H, Sakamoto H, Kumagai H, Abe T, Ishiguro S, Uchida K et al. Clinical Guidelines for Diagnosis and Management of Peutz-Jeghers Syndrome in Children and Adults. Digestion. 2023;104(5):335–347. https://doi.org/10.1159/000529799.

19. Friedlander JA, Liu QY, Sahn B, Kooros K, Walsh CM, Kramer RE et al. Capsule Endoscopy Clinical Report. J Pediatr Gastroenterol Nutr. 2017;64(3):485–494. https://doi.org/10.1097/mpg.0000000000001413.

20. Isoldi S, Cucchiara S, Repici A, Lerner DG, Thomson M, Oliva S. Gastrointestinal endoscopy in children and adults: How do they differ? Dig Liver Dis. 2021;53(6):697–705. https://doi.org/10.1016/j.dld.2021.02.016.

21. Liao Z, Gao R, Xu C, Li ZS. Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review. Gastrointest Endosc. 2010;71(2):280–286. https://doi.org/10.1016/j.gie.2009.09.031.

22. Панфилова ВН, Королев ПМ, Шавров АА (мл.), Харитонова АЮ, Шавров АА, Федотов ЛЕ и др. Детская эндоскопия. СПб.; 2020. Режим доступа: https://endoexpert.ru/stati/detskaya-endoskopiyametodicheskie-rekomendatsii-rendo/.

23. Bandorski D, Kurniawan N, Baltes P, Hoeltgen R, Hecker M, Stunder D, Keuchel M. Contraindications for video capsule endoscopy. World J Gastroenterol. 2016;22(45):9898–9908. https://doi.org/10.3748/wjg.v22.i45.9898.

24. Galyaev AV, Likutov AA, Arkhipova OV, Mtvralashvili DA, Veselov VV. Actual questions of preparation to videocapsule endoscopy. Koloproktologia. 2018;(1):21–26. (In Russ.) https://doi.org/10.33878/2073-7556-2018-0-1-21-26.

25. Lin L, Liu K, Liu H, Xin J, Sun Y, Xia S et al. Small intestinal mucosal abnormalities using video capsule endoscopy in intestinal lymphangiectasia. Orphanet J Rare Dis. 2023;18(1):308. https://doi.org/10.1186/s13023-023-02914-z.

26. Makarov IV, Sidorov AYu, Zhdanov AV, Zaytsev VE, Korolev DA, Shibanov VYa et al. Rare findings of capsule endoscopy. Clinical observation. Bulletin of the Medical Institute “REAVIZ” (Rehabilitation, Doctor and Health). 2024;14(4): 106–112. (In Russ.) https://doi.org/10.20340/vmi-rvz.2024.4.CASE.4.

27. Danilov MA, Atroshchenko AO, Chudnykh SM, Shcherbakov PL, Khatkov IE. Clinical Case: Intestinal Obstruction as Consequence of Capsule Endoscopy in Patient with Crohn’s Disease. Doktor.Ru. 2016;(1):54–58. (In Russ.) Available at: https://journaldoctor.ru/catalog/gastroenterologiya/neprokhodimost-kishechnika-posledstvie-kapsulnoy-endoskopiiu-patsienta-s-boleznyu-krona-klinicheski/.

28. Akopova AO, Parfenov AI, Shcherbakov PL, Mikheeva OM. The role of capsule endoscopy in the diagnosis of small intestine angiodysplasia. Farmateka. 2019;26(2):136–139. (In Russ.) https://doi.org/10.18565/pharmateca.2019.2.136-139.

29. Kashchenko VA, Raspereza DV, Akimov VP. Video capsule endoscopy in diagnostics of gastrointestinal bleedings. Novosti Khirurgii. 2013;21(1):64–69. (In Russ.) Available at: https://vkashchenko.ru/news/WebPage3.pdf.

30. Belysheva TS, Nasedkina TV, Valiev TT, Matinyan NV, Malikhova OA, Semenova VV et al. Peutz–Jeghers syndrome: a multidisciplinary approach to diagnosis based on a clinical case. Russian Journal of Pediatric Hematology аnd Oncology. 2021;8(4):95–102. (In Russ.) https://doi.org/10.21682/2311-1267-2021-8-4-95-102.

31. Yamamoto H, Sakamoto H, Kumagai H, Abe T, Ishiguro S, Uchida K et al. Clinical Guidelines for Diagnosis and Management of Peutz-Jeghers Syndrome in Children and Adults. Digestion. 2023;104(5):335–347. https://doi.org/10.1159/000529799.

32. Osmanov IM, Koshurnikova AS, Skorobogatova EV, Vinokurov AV. Experience of an outpatient endoscopy center based at a children’s hospital. Moskovskaya Meditsina. (In Russ.) Available at: https://niioz.ru/upload/iblock/179/c6ats7u1n0hxy8sun029zulr56k1lv1w.pdf.

33. Lokhmatov MM, Budkina TN, Oldakovsky VI, Diakonova EU. Peutz-Jeghers Syndrome: Diagnostic and Therapeutic Possibilities of Modern Intraluminal Endoscopy as Shown on Own Clinical Observations. Pediatric pharmacology. 2016;13(4):395–398. (In Russ.) https://doi.org/10.15690/pf.v13i4.1614.


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For citations:


Koshurnikova AS, Osmanov IM, Skorobogatova EV, Dmitrieva YA, Zakharova IN. The role of video capsule endoscopy in children with intestinal diseases. Meditsinskiy sovet = Medical Council. 2025;(19):122–129. (In Russ.) https://doi.org/10.21518/ms2025-363

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ISSN 2079-701X (Print)
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