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Some aspects of the background symptomatic treatment of cognitive impairment of various severity types

https://doi.org/10.21518/2079-701X-2013-12-50-54

Abstract

This literature review outlines the role of glutamatergic disturbances in the pathogenesis of cognitive disorders. There is data on the effectiveness of the glutamate NMDA-receptors antagonist - memantine - in patients with various dementias: Alzheimer's disease, dementia with Lewy bodies, vascular and mixed dementia. The authors share own positive experience with the drug Akatinol Memantine at various dementias. Options for administration of the drug in patients with mild cognitive impairment are discussed; results of a multicenter regional study are provided. The efficacy and safety of Akatinol Memantine as a medication to improve cognitive function is highlighted.

About the Author

I. S. Preobrazhenskaya
First MSMU named after I.M.Sechenov
Russian Federation


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For citations:


Preobrazhenskaya IS. Some aspects of the background symptomatic treatment of cognitive impairment of various severity types. Meditsinskiy sovet = Medical Council. 2013;(12):50-54. (In Russ.) https://doi.org/10.21518/2079-701X-2013-12-50-54

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