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POSSIBILITIES OF MIFEPRISTONE USE AFTER SURGICAL THERAPY OF UTERINE MYOMA

https://doi.org/10.21518/2079-701X-2016-12-142-145

Abstract

The effectiveness  of mifepristone (Gynestril) use in patients after surgical therapy of uterine myoma (laparoscopic myomectomy, embolization of uterine arteries, hysteroresectoscopy) was studied. It was shown that use of mifepristone at a dosage 50 mg per day in an intermittent regime for 3 months after surgical therapy main myoma of a uterus led to statistically significant reduction of the uterine volume in 96% of women (p < 0.05) and reduction of recurrence of uterine myoma for a year after the drug withdrawal.

About the Authors

S. V. Apresyan
Inozemtsev Municipal Clinical Hospital, Moscow
Russian Federation

MD, Prof.



V. I. Dimitrova
Inozemtsev Municipal Clinical Hospital, Moscow
Russian Federation

PhD  in medicine



O. A. Slyusareva
Inozemtsev Municipal Clinical Hospital, Moscow
Russian Federation

PhD in medicine



References

1. Андреева Е.Н., Рябинкина Т.С., Рыжова Т.Е. Минздрав настоятельно рекомендует. Обзор нового клинического протокола диагностики и лечения миомы матки. Status Praesens, 2016, 2[31]04: 41-50./Andreeva E.N., Ryabinkina T.S., Ryzhova T.E. Ministry of Health highly recommends. Review of a new clinical protocol of diagnostics and therapy of uterine myoma. Status Praesens, 2016, 2[31]04:41-50.

2. Радзинский В.Е., Тотчиев Г.Ф. Миома матки: курс на органосохранение. Информационный бюллетень. М.: редакция Status Praesens, 2014. 24 с./Radzinsky V.E., Totchiev G.F. Uterine myoma: course at organ preservation. Information bulletin. M.: Edition of Status Praesens, 2014. 24 p.

3. Миома матки: диагностика, лечение и реабилитация: Клинические рекомендации (протокол лечения) М., Минздрав России, 2015. 349с./Uterine myoma: diagnostics, therapy and rehabilitation: Clinical recommendations (protocol of therapy) M, Ministry of Health of Russia, 2015. 349 p.

4. Marsh EE, Ekpo GE, Cardozo ER et al. Racial differences in fibroid prevalence and ultrasound findings in asymptomatic young women (18-30 years old): a pilot stude. Fertil. Ster., 2013, 99(7): 1951-1957.

5. Baird DD, Harmon QE, Upson K et al. A prospective, ultrasound-based study to evaluate risk factors for uterine fibroid incidence and growth: methods and resultsof Recruitment. J. Womens Health., 2015, 24(11): 907-915.

6. Corona LE, Swenson CW, Sheetz KH et al. Use of other treatments before hysterectomy for benign conditions in a statewide hospital collaborative. J. Obstet. Gynecol., 2015, 212: 304.

7. Лебедев В.А., Давыдов А.И., Пашков В.М. Спорные и нерешенные вопросы лечения и профилактики миомы матки у больных репродуктивного периода. Трудный пациент, 2013, 11(8–9): 14-19./Lebedev V.A., Davydov A.I., Pashkov V.M. Disputable and unresolved issues of therapy and prevention of uterine myoma in reproductive period patients. Trudny patsient, 2013, 11 (8—9): 14-19.

8. Политова А.К. Оптимизация хирургического лечения больной миомой матки: автореф. дисс….докт. мед. наук. М., 2014. 52 с./Politova A.K. Optimization of surgical therapy of uterine myoma patient: extended abstract of the Doctor of Medicine dissertation. M, 2014. 52 p.

9. Laughlin SK. Individualizing the approach to a heterogeneous condition. Obstet. Gynecol. Author manuscript, available in PMC.

10. Беженарь В.Е., Павлова Н.Г., Прохорова В.С. Возможности применения Гинестрила при неоадъювантной терапии больных репродуктвиного возраста. Здоровье женщины, 2008, 4: 18-21./Bezhenar V.E., Pavlova N.G., Prokhorova V.S. Possibilities of Ginestril use at neoadjuvant therapy of reproductive age patients. Zdoroviye zhenschiny, 2008, 4: 18-21.

11. Самойлова Т.Е. Перспективы применения мифепристона в лечении миомы матки. Информационный бюллетень. М., 2015./ Samoylova T.E. Prospects of mifepristone use in therapy of uterine myoma. Information bulletin. M., 2015.


Review

For citations:


Apresyan SV, Dimitrova VI, Slyusareva OA. POSSIBILITIES OF MIFEPRISTONE USE AFTER SURGICAL THERAPY OF UTERINE MYOMA. Meditsinskiy sovet = Medical Council. 2016;(12):142-145. (In Russ.) https://doi.org/10.21518/2079-701X-2016-12-142-145

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)