Preview

Meditsinskiy sovet = Medical Council

Advanced search

The choice of combination antihypertensive therapy in patients with type 2 diabetes

https://doi.org/10.21518/2079-701X-2015-12-6-11

Abstract

The article tells about optimum choice of combination antihypertensive therapy in patients with diabetes mellitus 2. The article discusses the efficacy of combination therapy based on two types of RAAS blockade (angiotensin-converting enzyme inhibitor or angiotensin II receptor antagonist) with indapamide retard and amlodipine, and the treatment regimen without RAAS blockers, which is based on the combination of dihydropyridine calcium channel blocker, indapamide retard and cardioselective beta blocker. The clinical experience with the three mentioned schemes of anti-hypertensive therapy is described; the benefits of combination of perindopril and amlodipine prior to valsartan and amlodipine or amlodipine and metoprolol succinate are demonstrated.

About the Authors

O. A. Koshelskaya
Tomsk Research Institute of Cardiology
Russian Federation


O. A. Zhuravleva
Tomsk Research Institute of Cardiology
Russian Federation


R. S. Karpov
Tomsk Research Institute of Cardiology
Russian Federation


References

1. IDF Diabetes Atlas. 5th edition. 2011/2012. Available from: http://www.idf.org/diabetesatlas.

2. Sowers JR, Whaley-Connell A, Hayden M. The role of overweight and obesity in the cardiore-nal syndrome. Cardiorenal Med, 2011, 1:5-12.

3. Sowers JR. Diabetes mellitus and vascular disease. Hypertension, 2013, 61(5): 943-947.

4. Dedov II, Shestakova MV. Standarts of specialized diabetes care, 7th Edition. Diabetes mellitus J., 2015, 18(1): 1-112. Russian. (Дедов И.И., Шестакова М.В. Алгоритмы специализированной медицинской помощи больным сахарным диабетом, 7-й выпуск. Сахарный диабет, 2015, (1): 1-112).

5. Dedov II, Shestakova MV. Standarts of specialized diabetes care, 6th Edition. Diabetes mellitus J., 2013, 18(1): 1-120. Russian. (Дедов И.И., Шестакова М.В. Алгоритмы специализированной медицинской помощи больным сахарным диабетом, 6-й выпуск. Сахарный диабет, 2013, (1):1-120).

6. Mancia G, Fagard R, Narkiewicz K et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension. J Hypertens, 2013, 31(7): 1281-1357.

7. Bangalore S, Kumar S, Lobach I, Messerli FH. Blood pressure targets in subjects with type 2 diabetes mellitus/impaired fasting glucose. Observations from traditional and bayesian random-effects meta-analyses of randomized trials. Circulation, 2011, 123: 2799-2810.

8. Wald DS, Law М, Morris JK et al. Combination therapy versus monotherapy in reduction blood pressure: meta-analysis on 11000 participants from 42 trials. Am J Med, 2009, 122: 290-300.

9. Ruggenenti Р, Fassi А, Ilieva АР et al. Preventing Microalbuminuria in Type 2 Diabetes. New Engl J Med, 2004, 351: 1941-1951.

10. Brenner ВМ, Cooper МЕ, de Zeeuw D et al. Reductions of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL). JRAAS, 2000, 1: 328-335.

11. Parving НН, Lehnert Н, Brochner-Mortensen J et al. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. New Engl J Med, 2001, 345: 870-878.

12. Tatti Р, Pahor М, Byington RP et al. Outcome results of the Fosinopril versus Amlodipine Cardiovascular Events randomized Trial (FACET) in patients with hypertension and NIDDM. Diabetes Care, 1998, 21: 597-603.

13. Terpstra WF, May JF, Smit AJ et al. Long-term effects of amlodipine and lisinopril on left ventricular mass and diastolic function in elderly, previously untreated hypertensive patients: the ELvErA trial. Hypertension, 2001, 19: 303-309.

14. Dahlof В, Sever PS, Poulter NP et al. ASCOT Investigators Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet, 2005, 336: 895-906.

15. Jamerson К, Weber МА, Bakris GL et al. Benazepril plus amlodipine or hydrochlorothi-azide for hypertension in high-risk patients. New Engl J Med, 2008, 359: 2417-2428.

16. Elliott HL, Meredith PA. Preferential benefits of nifedipine GITS in systolic hypertension and in combination with RAS blockade: further analysis of the 'ACTION' database in patients with angina. J Human Hypertension, 2011, 25: 63-70.

17. Mochizuki S, Dahlof В, Shimizu М et al. Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): a randomised, open-label, blinded endpoint morbidity-mortality study. Lancet, 2007, 369: 1431-1439.

18. Bertrand МЕ, Ferrari R, Remme WJ et al. Clinical synergy of perindopril and calcium-channel blocker in the prevention of cardiac events and mortality in patients with coronary artery disease. Post hoc analysis of the EUROPA study. Am Heart J, 2010, 159: 795-802.

19. Cheng J, Zhang W, Zhang X et al. Effect of angi-otensin-converting enzyme inhibitors and angiotensin II receptor blockers on all-cause mortality, cardiovascular deaths, and cardiovascular events in patients with diabetes mellitus. JAMA, 2014, 174: 773-785.

20. Wu H-Y, Huang J-W, Lin H-J et al. Comparative effectiveness of renin-angiotensin system blockers and other antihypertensive drugs in patients with diabetes: systematic review and Bayesian network meta-analysis. BMJ, 2013, 347: f6008 (Published 24 October 2013).

21. Gress TW, Nieto J, Shahar E et al. Hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus. Atherosclerosis Risk in Communities Study. New Engl J Med, 2000, 13: 905-912.

22. Koshelskaya OA, Zhuravleva OA, Karpov RS. Effect of target blood pressure achieved during combined antihypertensive therapy on intrare-nal vascular resistance in hypertensive diabetic patients. System Hypertension J., 2013, 10(3): 60-65. Russian. (О.А. Кошельская, О.А. Журавлева, РС. Карпов. Влияние разных схем антигипертензивной терапии с достижением целевых значений артериального давления на состояние функции почек и внутрипочеч-ное сосудистое сопротивление у больных сахарным диабетом типа 2. Системные гипер-тензии, 2013, 10(03): 60-65).

23. Estacio RO, Jeffers BW, Gifford N, Schrier RW, Effect of blood pressure control on diabetic microvascular complications in patients with hypertension and type 2 diabetes. Diabetes Care, 2000, 23(2): 54-64.

24. Mackie FE, Meyer TW, Campbell DJ. Effects of antihypertensive therapy on intrarenal angioten-sin and bradykinin levels in experimental renal insufficienty. Kidney Int, 2002, 61: 555-563.

25. Wagner С, Kramer ВК, Hinder М et al. T-type and L-type calcium channel blockers exert opposite effects on renin secretion and renin gene expression in conscious rat. Br J Pharmacol, 1998, 124: 579-585.

26. Munakata М, Imai Y, Hashimoto J et al. The influence of antihypertensive agents on circa-dian rhythms of blood pressure and heart rate in patients with essential hypertension. Tohoku J Exp Med, 1992, 166: 217-227.

27. Platt J, Rubin J, Ellis J. Diabetic nephropathy: evaluation with renal duplex Doppler US. Radiology, 1994, 190: 343-346.

28. Radermacher JJ. Echo-doppler to predict the outcome for renal artery stenosis. Nephrologie, 2002, 15(6): 69-76.

29. Karpov RS, Koshelskaya OA. A circadian profile of arterial pressure in hypertensive patients with diabetes mellitus: relation with affected renal circulation. Ther arch, 2007, 79(12): 12-18. Russian (Р.С. Карпов, О.А. Кошельская. Суточный профиль артериального давления у больных с сочетанием артериальной гипертонии и сахарного диабета: связь с нарушением кровоснабжения почек. Терапевтический архив, 2007, 79(12): 12-18).

30. Asmar R, London GM, O'Rourke МЕ, Safar МЕ. Improvement in blood pressure, arterial stiffness and wave reflections with a very-low-dose perindopril/indapamide combination in hypertensive patients. A comparison with aten-olol. Hypertension, 2001, 38: 922-926.


Review

For citations:


Koshelskaya OA, Zhuravleva OA, Karpov RS. The choice of combination antihypertensive therapy in patients with type 2 diabetes. Meditsinskiy sovet = Medical Council. 2015;(12):6-11. (In Russ.) https://doi.org/10.21518/2079-701X-2015-12-6-11

Views: 355


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)