Preview

Meditsinskiy sovet = Medical Council

Advanced search

Post-stroke cognitive impairment and treatment options

https://doi.org/10.21518/2079-701X-2015-5-24-27

Abstract

Cognitive impairment is a widespread serious complication of ischemic stroke requiring intensive medication treatment. Citicoline is a medicine with proven efficacy in ischemic stroke and vascular cognitive impairment. The article provides an overview of trials on the use of citicoline in patients with cognitive impairment and vascular dementia.

About the Author

A. N. Bogolepova
Neurosurgery and Medical Genetics of the Russian National Research Medical University named after N.I. Pirogov, Moscow
Russian Federation


References

1. Naghavi M, Wang H, Lozano R et al. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 2015, 385 (9963): 117-171.

2. Стаховская Л.В., Клочихина О.А., Богатырева М.Д., Коваленко В.В. Эпидемиология инсульта в России по результатам территориально-популяционного регистра (2009-2010). Журнал неврологии и психиатрии им. С.С. Косакова, 2013, 5: 4-10.

3. Гусев Е.И., Мартынов М.Ю., Камчатнов П.Р Ишемический инсульт. Современное состояние проблемы. Доктор.ру, 2013, 5(83): 2-7.

4. Feigin VL, Forouzanfar MH, Krishnamurthi R et al. Global and regional burden of stroke in 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet, 2013, 382: 1-12.

5. Pendlebury ST, Rothwell PM. Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis. Lancet Neurol., 2009, 8(11): 1006-1018.

6. Гусев Е.И., Боголепова А.Н. Когнитивные нарушения при цереброваскулярных заболеваниях. М., МЕДпрессинформ, 2013: 160.

7. Barba R, Martinez-Espinosa S, Rodriquez-Garcia E et al. Poststroke dementia: clinical features and risk factors. Stroke, 2000, 31: 1494-1501.

8. Pohjasvaara T, Erkinjuntti T, Vataja R, Kaste M. Dementia three months after stroke: baseline frequency and effect of different definitions for dementia in the Helsinki Aging Memory Study (SAM) cohort. Stroke, 1997, 28: 785-792.

9. Kase CS, Wolf PA, Kelly-Hayes M et al. Intellectual decline after stroke. The Framingham study. Stroke, 1998, 29: 805-812.

10. Leys D, Неnon H, Mackowiak-Cordoliani MA, Pasquier F. Poststroke dementia. Lancet Neurol, 2005, 752-759.

11. Шахпаронова Н.В., Кадыков А.С. Нейропро-текторная терапия в реабилитации больных с постинсультными когнитивными нарушениями и в профилактике деменции при хронических сосудистых заболеваниях мозга. Атмосфера. Нервные болезни, 2011, 1: 23-26.

12. Боголепова А.Н. Критерии диагностики и прогноза ишемического инсульта (клинико-ней-ропсихологическое исследование): Автореф. дис.. докт. мед. наук. М., 2003.

13. Ojala-Oksala J, Jokinen H, Kopsi V et al. Educational History Is an Independent Predictor of Cognitive Deficits and Long-Term Survival in Postacute Patients With Mild to Moderate Ischemic Stroke. Stroke, 2012, 43: 2931-2935.

14. Jacquin A, Binquet C, Rouaud O, Graule-Petot A, Daubail B, Osseby GV, Bonithon-Kopp C, Giroud M, Bejot Y Post-stroke cognitive impairment: high prevalence and determining factors in a cohort of mild stroke. J Alzheimers Dis, 2014, 40(4): 1029-1038.

15. Blanco-Rojas L, Arboix A, Canovas D. Cognitive profile in patients with a first-ever lacunar infarct with and without silent lacunes: a comparative study. BMC Neurology, 2013, 13: 203.

16. Wagle J, Farner L, Flekkoy K et al. Association between ApoE e4 and cognitive impairment after stroke. Dementia Geriatr Cogn Disord, 2009, 27: 525-533.

17. Pasquier F, Leys D. Why are stroke patients prone to develop dementia? J Neurol, 1997, 244: 135-142.

18. Захаров В.В., Вахнина Н.В. Особенности ведения пациентов с постинсультными когнитивными нарушениями. Атмосфера. Нервные болезни, 2011, 3: 14-20.

19. Melkas S, Oksala NK, Jokinen H, et al. Poststroke dementia predicts poor survival in long-term follow-up: influence of prestroke cognitive decline and previous stroke. J Neurol Neurosurg Psychiatry, 2009, 80: 865-870.

20. Hurtado O, Cardenas A, Pradillo JM, Morales JR, Ortego F, Sobrino T, Castillo J, Moro MA, Lizasoain I. A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke. Neurobiol Dis, 2007, 26: 105-111.

21. Мунис М. Цитиколин улучшает нейрорегене-ративные процессы после экспериментального инсульта у крыс. Stroke, 2012, 3: 56-64.

22. Lee HJ, Kang JS, Kim YI. Citicoline protects against cognitive impairment in a rat model of chronic cerebral hypoperfusion. J Clin Neurol, 2009, 5: 33-38.

23. Warach S, Pettigrew LC, Dashe JF, Pullicino P Lefkowitz DM, Sabounjian L, Harnett K, Schwiderski U, Gammans R. Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Citicoline 010 Investigators. Ann Neuro, 2000, 48: 713-722.

24. Мартынов М.Ю., Бойко А.Н., Камчатнов П.Р. с соавт. Нейропротективная терапия цитиколи-ном (цераксон) у больных с ишемическим инсультом. Журнал неврологии и психиатрии им. С.С. Корсакова, 2012, 3, Вып. 2: 21-26.

25. Alvarez-Sabin J, Roman GC. Citicoline in vascular cognitive impairment and vascular dementia after stroke. Stroke, 2011, 42: 40-43.

26. Alvarez-Sabin J, Ortega G, Jacas C, Ouintana M, Ribo M, Santamarina E, Maisterra O, Molina C, Montaner J, Roman G. Citicoline treatment prevents neurocognitive decline after a first ischemic stroke (Poster 743). Cerebrovasc Dis, 2010, 29(2): 268.

27. Fioravanti M, Yanagi M. Cytidinediphospho-choline (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev 2005;18:CD000269.

28. Cotroneo A.M., Castagna A., Putignano S. et al. Effectiveness and safety of citicoline in mild vascular cognitive impairment: the IDEALE study. Clin IntervAging, 2013, 8: 131-137.

29. Garcia-Cobos R, Frank-Garcia A, Gutierrez-Fernandez M, Diez-Tejedor E. Citicoline, use in cognitive decline: vascular and degenerative. Journal of the Neurological Sciences, 2010, 299: 188-192.

30. Cho H-J, Kim YJ. Efficacy and safety of oral citicoline in acute ischemic stroke: drug surveillance study in 4191 cases. Methods Find Exp Clin Pharmaco, 2009, 31(3): 171-176.


Review

For citations:


Bogolepova AN. Post-stroke cognitive impairment and treatment options. Meditsinskiy sovet = Medical Council. 2015;(5):24-27. (In Russ.) https://doi.org/10.21518/2079-701X-2015-5-24-27

Views: 639


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)