INFLUENCE OF GINKGO BILOBA LEAF EXTRACT EGb 761 IN MONOTHERAPY ON SUBJECTIVE EAR NOISE
https://doi.org/10.21518/2079-701X-2017-8-76-79
Abstract
The results of treatment by Memoplant drug as monotherapy (120 mg, 2 times a day for 4 months) on the subjective ear noise and hearing function of 40 people are presented. Comprehensive audiological, neurological examination was conducted in the dynamics to all patients as well as the study of mental and emotional status. It is established that on Day 14 of the study, the patients subjectively reported a decrease in the intensity of ear noise. Significant improvement of tolerance to ear noise was recorded on Day 120 of the study. It was noted that the Memoplant effects the psychoemotional status of patients (subjectively reduces anxiety and depression significantly to Day 60 of the study). Side effects have not been identified.
About the Authors
N. L. Kunelskaya
Sverzhevsky Research and Clinical Institute of Otorhinolaryngology of the Moscow Health Department; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
MD, Prof.
E. S. Yanushkina
Sverzhevsky Research and Clinical Institute of Otorhinolaryngology of the Moscow Health Department
Russian Federation
Russian Federation
PhD in medicine
E. V. Baybakova
Sverzhevsky Research and Clinical Institute of Otorhinolaryngology of the Moscow Health Department
Russian Federation
Russian Federation
PhD in medicine
М. A. Chugunova
Sverzhevsky Research and Clinical Institute of Otorhinolaryngology of the Moscow Health Department
Russian Federation
Russian Federation
PhD in medicine,
M. V. Tardov
Sverzhevsky Research and Clinical Institute of Otorhinolaryngology of the Moscow Health Department
Russian Federation
Russian Federation
MD
Z. O. Zaoeva
Sverzhevsky Research and Clinical Institute of Otorhinolaryngology of the Moscow Health Department
Russian Federation
Russian Federation
G. N. Isotova
Sverzhevsky Research and Clinical Institute of Otorhinolaryngology of the Moscow Health Department
Russian Federation
Russian Federation
PhD in biology
References
1. Hoffman HJ, Reed GW. Epidemiology of tinnitus. In: Snow J.B. Tinnitus: Theory and Management. Hamilton, Ontario: BC Decker. 2004: 16-41.
2. Adjamian P, Sereda M, Hall DA. The mechanisms of tinnitus: perspectives from human functional neuroimaging. Hear Res, 2009, 253: 15-31.
3. Jastreboff P. A neurophysiological approach to tinnitus: clinical implication. British Journal of audiology, 1993, 27(1): 11.
4. Jastreboff PJ. Fantom auditor perception (tinnitus), mechanisms of generation and perception. Neurosci. Res., 1990, 8: 221-254.
5. Møller AR, Langguth B, Ridder DD, Kleinjung T. Textbook of tinnitus. Springer. New York. 2011: 785.
6. Krog NH, Engdahl B, Tambs K. The association between tinnitus and mental health in a general population sample: results from the HUNT Study. J Psychom Res, 2003, 6: 289-298.
7. Резакова Н.В. Взаимосвязь субъективного ушного шума и головокружений с психоэмоциональными нарушениями: дис. … канд. мед. наук. М., 2015.
8. Гуненков А.В., Косяков С.Я. Субъективный ушной шум. Современные представления о лечении. Вестн. оторинолар., 2014, 3: 72-75.
9. Пальчун В.Т., Кунельская Н.Л., Полякова Т.С. Лечение острой нейросенсорной тугоухости. Вестн. оторинолар., 2006, 3: 45-48.
10. Morgenstern C, Biermann E. The efficacy of Ginkgo biloba Special Extract EG 761 in patients with tinnitus. Int J Clin Farmacol Ther, 2002, 40: 188-197.
11. Moeller CK, Kurt S, Scheich H, Schulze H. Improvement of auditory discrimination learning by Ginkgo biloba extract EG 761. Neuroscience Letters, 2009, 463(3): 219-222.
12. Von Boetticher A. Ginkgo biloba extract in the treatment of tinnitus: a systematic review. Neuropsychiatr Dis Treat, 2011, 7: 441-447.
Review
For citations:
Kunelskaya NL, Yanushkina ES, Baybakova EV, Chugunova МA, Tardov MV, Zaoeva ZO, Isotova GN. INFLUENCE OF GINKGO BILOBA LEAF EXTRACT EGb 761 IN MONOTHERAPY ON SUBJECTIVE EAR NOISE. Meditsinskiy sovet = Medical Council. 2017;(8):76-79. (In Russ.) https://doi.org/10.21518/2079-701X-2017-8-76-79
Views:
13357
Email this article 