Combined therapy of allergic reactions in the acute period

Abstract

Managing exacerbation of an allergic diseases is a challenge addressed with a toolkit of pharmaceutical and non-pharmaceutical measures. Despite a fairly wide range of medicines used in the treatment of allergic exacerbations affecting various organs and systems, anti-histamines and steroids remain the most commonly used medicines. These groups of medicines have the most profound clinical effects associated with the pharmacological characteristics of the drugs, allowing for quite a prompt action at virtually all stages of allergic reaction. Other antihistamine medications such as leukotriene receptor antagonists, mast cell stabilizers and others, are also quite widely used in practical allergology. The key task of allergist/immunologist is to choose the correct way of managing a patient during the exacerbation period, to find the appropriate antiallergic therapy tailored to the individual characteristics of the patient, the course and severity of the acute phase.