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New prospects in the management of functional reproductive disorders associated with polycystic ovary syndrome

https://doi.org/10.21518/2079-701X-2015-9-34-38

Abstract

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age associated with hyperandrogenism, anovulatory infertility and metabolic disorders. Along with hormonal therapy, reproductive disorders associated with polycystic ovary syndrome are managed with the help of drugs which increase insulin sensitivity, reduce secretion of insulin and androgens. A literature review demonstrated that myo-inositol, one of nine stereoisomers of hexa-hydroxy alcohol inositol, also helps to regulate the menstrual cycle, restore ovulation and maturation of oocytes, as well as reduces insulin resistance and hyperandrogenism. Myo-inositol seems to be promising in the treatment of PCOS and significantly improves IVF results.

About the Authors

G. E. Chernukha
Scientific center for obstetrics, gynecology and perinatology named after V.I. Kulakov, Russia’s Ministry of Health, Moscow
Russian Federation


E. K. Kaprina
Scientific center for obstetrics, gynecology and perinatology named after V.I. Kulakov, Russia’s Ministry of Health, Moscow
Russian Federation


A. A. Naidukova
Scientific center for obstetrics, gynecology and perinatology named after V.I. Kulakov, Russia’s Ministry of Health, Moscow
Russian Federation


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Review

For citations:


Chernukha GE, Kaprina EK, Naidukova AA. New prospects in the management of functional reproductive disorders associated with polycystic ovary syndrome. Meditsinskiy sovet = Medical Council. 2015;(9):34-38. (In Russ.) https://doi.org/10.21518/2079-701X-2015-9-34-38

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)