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Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy

https://doi.org/10.21518/2079-701X-2019-1-24-30

Abstract

The article discusses the principles of neuroprotective therapy as a pathogenetically justified direction in chronic cerebrovascular diseases (CVD). The results of numerous clinical trials demonstrated efficacy, safety, a wide range of pharmacological effects and good tolerability of the powerful antioxidant Idebenone (Neyromet), as well as domestic cytoprotector, Choline alphosceratus of (Cerepro®), affecting the basic pathophysiological processes of the ischemic cascade at CVD. The role of rational multimodal pharmacotherapy of CVD, which provides the necessary energy for the processes of neuroprotection and neuroplasticity of brain cells, is emphasized.

About the Authors

E. V. Kostenko
Moscow State Autonomous Healthcare Institution «Moscow Scientific and Practical Centre of Medical Rehabilitation, Restorative and Sports Medicine of Moscow Health Care Department»; Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of Russia
Russian Federation
Dr. of Sci. (Med.)., Professor of Chair of Neurology, Medical Genetics and Neurosurgery, Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation, a lead researcher, Head of Branch 7 of Moscow Autonomous Healthcare Institution “Moscow State Autonomous Healthcare Institution «Moscow Scientific and Practical Centre of Medical Rehabilitation, Restorative and Sports Medicine of Moscow Health Care Department»


L. V. Petrova
Moscow State Autonomous Healthcare Institution «Moscow Scientific and Practical Centre of Medical Rehabilitation, Restorative and Sports Medicine of Moscow Health Care Department»
Russian Federation
Cand. of Sci. (Med.), Head of Branch 7 of Moscow Autonomous Healthcare Institution «Moscow Scientific and Practical Centre of Medical Rehabilitation, Restorative and Sports Medicine of Moscow Health Care Department»


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For citations:


Kostenko EV, Petrova LV. Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy. Meditsinskiy sovet = Medical Council. 2019;(1):24-30. (In Russ.) https://doi.org/10.21518/2079-701X-2019-1-24-30

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