Chronobiological features of primary headaches and the role of melatonin in the regulation of biological rhythms
https://doi.org/10.21518/2079-701X-2019-1-33-38
Abstract
Frequency is considered as a key sign of the course of some forms of primary headaches (PH). One of the most prominent representatives is the hypnical and cluster headache, which predetermined their name. Clinical observations demonstrate a clear circadian rhythm and seasonal pattern of cluster headache (CH) and migraine (M) attacks. In accordance with modern concepts, the phenomenon of the periodicity of painful episodes of a number of forms of primary headaches is associated with dysfunction of the suprachiasmatic nucleus of the hypothalamus, the main pacemaker of biological rhythms. The connection of PH with chronopathology is confirmed by revealing the disturbances of melatonin secretion in CH and M. Melatonin has proven to be effective in treatment of these PH.
About the Authors
E. M. Evdokimova
Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)
Russian Federation
neurologist, postgraduate student, Chair of Nervous Diseases and Neurosurgery at the Faculty of General Medicine, Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)
Russian Federation
neurologist, postgraduate student, Chair of Nervous Diseases and Neurosurgery at the Faculty of General Medicine, Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)
M. G. Poluektov
Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)
Russian Federation
neurologist, Associate Professor, Chair of Nervous Diseases and Neurosurgery at the Faculty of General Medicine, Federal State Autonomous Educational of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)
Russian Federation
neurologist, Associate Professor, Chair of Nervous Diseases and Neurosurgery at the Faculty of General Medicine, Federal State Autonomous Educational of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)
G. R. Tabeyeva
Federal State Autonomous Educational Institution of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)
Russian Federation
Dr. of Sci. (Med.), Professor, Chair of Nervous Diseases and Neurosurgery at the Faculty of General Medicine, Federal State Autonomous Educational of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)
Russian Federation
Dr. of Sci. (Med.), Professor, Chair of Nervous Diseases and Neurosurgery at the Faculty of General Medicine, Federal State Autonomous Educational of Higher Education «I.M. Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)
References
1. Halberg F. Chronobiology. Annual review of Physiology. 1969;31:675-725.
2. Foster R., Kretzman L. Rhythms of Life: The biological clocks That Control the Daily Lives of Every Living Thing. London; Profile, 2004.
3. Refinetti R. Circadian physiology. New York, USA; Taylor and Francis, 2006.
4. Baumel B., Eisner L.B. Diagnosis and treatment of headache in the elderly. Med. Clin. North Am. 1991;75:575-616.
5. Barloese M., Jennum P., Lund N., Jensen R.H. Sleep in cluster headache, beyond a temporal REM-relationship? European Journal of Neurology. 2015;22:656–664.
6. Terzaghi M., Ghiotto N., Sances G., Rustioni V., Nappi G., Manni R. Episodic cluster headache: NREM prevalence of nocturnal attacks Time to look beyond macrostructural analysis? Headache. 2010;50(6):1050–1054.
7. Fokin I.V. Clinical and psychological characteristics and cerebral pathogenetic mechanisms of cluster headache: Cand. of Sci. (Med.) Dissertation. M., 2000. 148 p. (In Russ).
8. Manzoni G.C., Bono G., Lanfranchi M., Micieli G., Terzano M.G. & Nappi G. Lithium carbonate in cluster headache: assessment of its short term and long term therapeutic efficacy. Cephalgia. 1983;3(2):109-114.
9. Barloese M., Lund N., Jensen R.H. Sleep in trigeminal autonomic cephalagias: A review. Cephalalgia. 2014;34(10):813–822.
10. Rozen T.D., Fishman R.S. Cluster headache in the United States of America: Demographics, clinical characteristics, triggers, suicidality, and personal burden. Headache. 2011;52: 99–113.
11. Ofte H.K., Berg D.H., Bekkelund S.I., Alstadhaug K.B. Insomnia and periodicity of headache in an Arctic cluster headache population. Headache. 2013;53:1602–1612.
12. Manzoni G.C., Terzano M.G., Bono G. Cluster headache – clinical findings in 180 patients. Cephalalgia. 1983, 3: 21–30.
13. Ferrari E., Canepari C., Bossolo P.A..Changes of biological rhythms in primary headache syndromes. Cephalalgia, 1983;3(1):58–68.
14. Leone M., D’Amico D., Moschiano F., Fraschini F., Bussone G. Melatonin versus placebo in the prophylaxis of cluster headache: A doubleblind pilot study with parallel groups. Cephalalgia. 1996;16(7):494–496.
15. Kudrow L. The cyclic relationship of natural illumination to cluster period frequency. Cephalalgia. 1987;7(6):76–82.
16. Alexeev V.V. Chronic headaches. Clinical manifestations, diagnosis, pathogenesis: extended abstract of Dr. of Sci. (Med.) Dissertation. M., 2006. (In Russ).
17. Osipova V.V. Tension headache: a practical guide for physicians. M.: OGGI. Reklamnaya Produktsiya, LLC, 2009. 44 p. (In Russ).
18. Bruera O., Sances G., Leston J., Levin G., Cristina S., Medina C. Plasma melatonin pattern in chronic and episodic headaches. Evaluation during sleep and waking. Functional Neurology. 2008;23(2):77-81.
19. Osipova V.V., Levin Ya.I. Migraine in the sleepwake cycle. Zhurnal Nevrologii i Psikhiatrii Im. S.S. Korsakova. 2006;106(5):9-15. (In Russ).
20. Dexter J.D., Riley T.L. Studies in nocturnal migraine. Headache. 1975;15(1):51-62.
21. Gori S., Morelli N., Maestri M., Fabbrini M., Bonanni E., Murri L. Sleep quality, chronotypes and preferential timing of attacks in migraine without aura. J. Headache Pain.2005;6:258-260.
22. Solomon G.D. Circadian rhythms and migraine. Cleve Clin J Med. 1992;59:326-329.
23. Fox AW., Davies R.L. Migraine chronobioilogy. Headache. 1998;38:436-441.
24. Gori S., Lucchesi C., Baldacci F., Bonuccelli U. Preferential occurrence of attacks during night sleep and/or upon awakening negatively affects migraine clinical presentation. Funct Neurol. 2015;30(2):119-123.
25. Alstadhaug K.B., Salvesen R., Bekkelung S. 24-hour distribution of migraine. Headache. 2008;48:95-100.
26. Soriani S., Fiumana E., Manfredini R., Boari B., Battistella PA., Canetta E. et al. Circadian and seasonal variation of migraine attacks in children. Headache. 2006;46:1571-1574.
27. Osipova V.V., Tabeeva G.R. Primary headaches: diagnosis, clinic manifestations, therapy. A practical guide. M.: Izdatelstvo “Meditsinskoye Informatsionnoye Agentstvo”, LLC, 2014. 336 p. (In Russ).
28. Torelli P., Cologno D., Manzoni G.C. Weekend headache: A possible role of work and lifestyle. Headache. 1999;39:398-408.
29. Cugini P., Romit A., Di Palma L., Giacovazzo M. Common migraine as weekly and seasonal headache. Chronobiology International. 1990;7:467-469.
30. Hoffmann J., Lo H., Neeb L., Martus P., Reuter U. Weather sensitivity in migraineurs. J. Neurol. 2011;258(4):596-602.
31. Alstadhaug K.B., Salvesen R., Bekkelung S.I. Seasonal variation in migraine. Cephalalgia. 2005;25:811-816.
32. Headache Classification Committee of the International Headache Society The International Classification of Headache Disorders. 3rd ed (beta version). Cephalalgia. 2013;33(9):629–808.
33. Deshumuk V.D. Retino-hypothalamic-pineal hypothesis in the pathophysiology of primary headaches. Medical Hypothesis. 2006;66:1146-1151.
34. Peres M.F., Sanchez del Rio M., Seabra M.L., Tufik S., Abucham J., Cipolla-Neto J. et al. Hypothalamic involvement in chronic migraine. J Neurol Neurosurg Psychiatry. 2001;71(6):747-51.
35. Ong J.C., Taylor H.L., Park M., Burgess H.J., Fox R.S., Snyder S. et al. Can Circadian Dysregulation Exacerbate Migraines? Headache. 2018;58(7):1040-1051.
36. Brennan K.C, Bates E.A., Shapiro R.E., Zyuzin J., Hallows W.C., Huang Y. Casein kinase iδ mutations in familial migraine and advanced sleep phase. Sci Transl Med., 2013;5:183ra56,1-183ra56,11.
37. Rivas-Martínez I., Ambite-Quesada S., Fernández-de-las-Peñas C., Arroyo-Morales M., Fernández-Mayoralas D.M., Linares-García-Valdecasas R. et al. Salivary cortisol and melatonin levels in children with frequent episodic tension-type headache do not differ from healthy children. Acta Paediatr. 2011;100(11):198-202.
38. Nagtegaal J.E., Smits M.G., Swart A.C., Kerkhof G.A., van der Meer YG. Melatonin-responsive headache in delayed sleep phase syndrome: preliminary observations. Headache. 1998;38(4):303-309.
39. Pacheco L.R., Latorraca de O.C.C, Freitas da Costa A.L.A, Martimbianco L.C.A, Pachito VD, Riera R. Melatonin for preventing primary headache: A systematic review. Int J Clin Pract. 2018;72(7):132-135.
40. Kurganova Yu.M., Danilov A.B. Melatonin in back pain and predictors of melatonin efficacy. Zhurnal Nevrologii i Psikhiatrii Im. S.S. Korsakova. 2017;117(10):49-54. (In Russ).
Review
For citations:
Evdokimova EM, Poluektov MG, Tabeyeva GR. Chronobiological features of primary headaches and the role of melatonin in the regulation of biological rhythms. Meditsinskiy sovet = Medical Council. 2019;(1):33-38. (In Russ.) https://doi.org/10.21518/2079-701X-2019-1-33-38
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