Preview

Meditsinskiy sovet = Medical Council

Advanced search

Possibilities of coenzyme q10 as a part of complex therapy of patients with chronic heart failure and its influence on indicators of quality of life

https://doi.org/10.21518/2079-701X-2019-5-90-95

Abstract

The research objective consisted in studying of influence of coenzyme Q10 as a part of complex therapy of patients with the chronic heart failure (CHF) on indicators of quality of life in comparison with traditional therapy without coenzyme Q10 addition. The research included 75 patients with CHF 1-3 of FC, the coronary heart disease (CHD) which complicated a current with a myocardial infarction in the anamnesis In comparative aspect were analyzed dynamics of physical and psychological components of quality of life of patients with CHF 1-3 of FC under the influence of traditional therapy and traditional therapy with coenzyme Q10 addition. The indicators of quality of life defined on the basis of questionnaires of EQ-5D-DL and SF-36, supplementing a disease picture, are multiple-factor criterion for evaluation of a condition of patients with CHF 1-3 of FC. Improvement of indicators of quality of life is more expressed under the influence of traditional therapy with coenzyme Q10 addition.

About the Authors

Zh. M. Sizova
Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University).
Russian Federation

Sizova Zhanna Mikhailovna – Dr. of Sci. (Med), Professor, Head of the Department of Medical and Social Expertise, Emergency and Polyclinic Therapy.

 8, Trubetskaya Street, Moscow, 119991, Russia, p. 2.



V. L. Zakharova
Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University).
Russian Federation

Zakharova Valeria Leonidovna – Candidate of Medical Sciences, Associate Professor of the Department of Medical and Social Expertise, Emergency and Polyclinic Therapy. 

 8, Trubetskaya Street, Moscow, 119991, Russia, p. 2.



K. A. Alibeyli
Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University); Federal State Budgetary Healthcare Institution «Central Medical and Sanitary Part No. 119 of the Federal Medical and Biological Agency».
Russian Federation

Alibeyli Keklik Ahmedaga kizi – post-graduate student of the Department of Medical and Social Expertise, Emergency and Polyclinic Therapy;  physician-therapist. 

 8, Trubetskaya Street, Moscow, 119991, Russia, p. 2; 127018, Russia, Moscow, Suschevsky Val str., 24. 



References

1. Mosterd A., Hoes A.W. Clinical epidemiology of heart failure. Heart. 2007; 93(9): 1137-46. DOI:10.1136/hrt. 2003.025270.

2. Polyakov D.S., Fomin I.V., Valikulova F.Yu. et al. The EPOCH-CHF epidemiological program: decompensated chronic heart failure in real-life clinical practice (EPOCH-D–CHF). Russian Heart Failure Journal. 2016;17(5):299–305. doi:10.18087/rhfj. 2016.5.2239. (In Russ).

3. Krom I.L., Erugina M.V., Sazanova G.Y. Assessment of health care in the context of quality of life with the patients with coronary heart disease. Fundamental researches. 2015;16:1174-1177. (In Russ).

4. Shalnova S.A., Konradi A.O., Karpov Yu.A. et al. Cardiovascular mortality in 12 Russian Federation regions – participants of the Cardiovascular Disease Epidemiology in Russian Regions study. Russ J Cardiol. 2012;5(97):6-11. (In Russ).

5. Amirdjanova V.N., Goryachev D.V., Korshunov N.I. et al. SF-36 questionnaire population quality of life indices Objective. Rheumatology Science and Practice. 2008;46(1):36-48. https://doi. org/10.14412/1995-4484-2008-852. (In Russ).

6. Ware J.Е., Snow К.К., Kosinski М., Gandek В. SF-36 Health Survey. Manuel and Interpretation Guide. Lincoln, RI’. QualityMetric Incorporated. 2000; 150 p.

7. Lahoud R., Brennan D., Cho L. Comparing SF-36 score versus biomarkers to predict mortality in primary cardiac prevention patients. J. Am. Coll. Cardiol. 2014;63(12):23-36.

8. Kashkina N.V., Botalov N.S., Nekrasovа J.E. The study of quality of life in patients with coronary artery disease using the sf-36 questionnaire. International Student Scientific Journal. 2018;5. URL: http://eduherald. ru/ru/article/view?id=18667. (In Russ).

9. Mal G.S., Dudka M.V., Bushueva O.Yu. et al. The study of quality of life in patients with coronary artery disease using the SF-36 questionnaire. Good Clinical Practice. 2016;2:52-56.

10. Afanasieva E.V. Estimate of quality of life associated with health. Good clinical practice. 2010;1:56-58.

11. Novik A.A., Ionova T.I. Guidance to research of the quality of life in medicine. St.Pb.: Neva; M.: Olma-Press Zvezdny mir, 2007; 320 p..

12. Ponomarev D.S. To the question of assessing the quality of life in patients with hypertension. International Journal of Humanities and Natural Sciences. 2014;1(3):168-173. (In Russ).

13. Kuvshinova N.Y. Assessment of life’s quality of ischemic heart disease patients taking into account their emotional and personal characteristics. Izvestia of Samara Scientific Center of the Russian Academy of Sciences. 2012;3(2):397-401. (In Russ).


Review

For citations:


Sizova ZM, Zakharova VL, Alibeyli KA. Possibilities of coenzyme q10 as a part of complex therapy of patients with chronic heart failure and its influence on indicators of quality of life. Meditsinskiy sovet = Medical Council. 2019;(5):90-95. (In Russ.) https://doi.org/10.21518/2079-701X-2019-5-90-95

Views: 840


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)