Functional dyspepsia: from pathogenesis to therapeutic aspects
https://doi.org/10.21518/2079-701X-2019-3-18-25
Abstract
Functional dyspepsia (FD) is one of the most common gastroenterological diseases. The article presents modern views on the pathogenesis of the disease. It is shown that disorders of motor skills (retardation of voiding function, disturbance of relaxation accommodation) and stomach sensitivity (visceral hypersensitivity to stretching) are considered to be one of the main pathophysiological mechanisms of FD. The authors present a modern algorithm of treatment of patients with FD, based on the clinical recommendations of the Rome Consensus IV revision (2016) and the Russian Gastroenterological Association (2017). The strategy of differentiated use of pharmaceuticals for different variants of FD is considered.
About the Authors
D. T. Dicheva
Federal State Budgetary Educational Institution of the Higher Education «Moscow State University of Medicine and Dentistry named after A.I. Yevdokimov» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Candidate of Medical Sciences, Associate Professor of the Department of Propaedeutics of Internal Diseases and Gastroenterology, gastroenterologist of «European Medical Center» JSC,
127473, Moscow, 20, Delegateskaya St.
Yu. S. Subbotina
Federal Public Health Institution «Main Clinical Hospital of the Ministry of Internal Affairs of the Russian Federation»
Russian Federation
Russian Federation
gastroenterologist, doctor of the Department of Radioisotope Diagnostics,
123060, Moscow, 35, Narodnogo Opolocheniya St.
L. G. Bektemirova
Federal State Budgetary Educational Institution of the Higher Education «Moscow State University of Medicine and Dentistry named after A.I. Yevdokimov» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
postgraduate student of the Department of Propaedeutics of Internal Diseases and Gastroenterology,
127473, Moscow, 20, Delegateskaya St.
D. N. Andreev
Federal State Budgetary Educational Institution of the Higher Education «Moscow State University of Medicine and Dentistry named after A.I. Yevdokimov» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Candidate of Medical Sciences, Associate Professor of the Department of Propaedeutics of Internal Diseases and Gastroenterology,
127473, Moscow, 20, Delegateskaya St.
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Review
For citations:
Dicheva DT, Subbotina YS, Bektemirova LG, Andreev DN. Functional dyspepsia: from pathogenesis to therapeutic aspects. Meditsinskiy sovet = Medical Council. 2019;(3):18-25. (In Russ.) https://doi.org/10.21518/2079-701X-2019-3-18-25
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