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Experience with a multi-strain probiotic in infants with functional gastrointestinal disorders

https://doi.org/10.21518/2079-701X-2015-14-48-53

Abstract

In 90% of infants, the introduction of complementary foods or transition to bottle or mixed feeding is characterized by changes in the frequency and type of stool, intestinal colic, regurgitation, flatulence. Administration of the multi-strain probiotic Bac-Set Baby for 14 days in infants with FGID allows to manage the changes in the frequency and type of stool in 80% of cases, symptoms of intestinal colic in 86% of children, regurgitation in 70%, and flatulence in 78% of children. Studies of the metabolic activity of obligate intestinal microorganisms demonstrated that multi-strain probiotic Bac-Set Baby (Probiotics International Ltd., UK) in children with FGID is effective in the management and restoration of the intestinal microbiota in children in the first year of life. The administration was associated with a tendency to restore the activity of the colonic obligate microflora, particularly bifido- and lactobacteria, due to changes in the qualitative composition of microorganisms characterized by reduced activity of facultative and residual anaerobic (in type 1) and aerobic (in type 2) microfloras, and improvement of the intraluminal environment. In addition, there was a tendency toward normalization of proteolysis and elimination of residual (opportunistic) microorganisms as a result of treatment.

About the Authors

I. N. Zakharova
Russian Medical Academy of Postgraduate Education
Russian Federation


N. G. Sugyan
Russian Medical Academy of Postgraduate Education; Outpatient Center №133
Russian Federation


M. D. Ardatskaya
Teaching and Research Medical Center of the RF Presidential Administration
Russian Federation


S. I. Lazareva
Outpatient Center №133
Russian Federation


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For citations:


Zakharova  IN, Sugyan  NG, Ardatskaya  MD, Lazareva  SI. Experience with a multi-strain probiotic in infants with functional gastrointestinal disorders. Meditsinskiy sovet = Medical Council. 2015;(14):48-53. (In Russ.) https://doi.org/10.21518/2079-701X-2015-14-48-53

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ISSN 2079-701X (Print)
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