Effect of hypoglycemic therapy on fat metabolism
Abstract
Diabetes mellitus (DM type 2) is a chronic, progressive heterogeneous disease. According to the WHO, the number of patients with DM type 2 is nearly 370 million people. In 80-90% of cases [1] DM type 2 is associated with obesity. Abdominal (visceral) fat distribution which is typical of DM type 2 is characterized by dyslipidemia, insulin resistance and hypertension [2]. The combination of obesity and DM type 2 greatly aggravates the course, increasing the cost of treatment and rehabilitation. Despite numerous efforts in healthcare, compensation stage is registered in less than one third of patients with DM type 2.
About the Author
M. S. Abayeva
Russian Medical Academy of Postgraduate Education, Department of Endocrinology and Diabetology
Russian Federation
Russian Federation
References
1. Diabetologie in Klinik und Praxis / Hrsg. von H. Mehnert. Stuttgart, New York, 1999.
2. Балаболкин М.И., Клебанова Е.М., Креминская В.М. Функциональная активность Р-клеток, состояние инсулиновой резистентности, секреция лептина и а-фактора некроза опухолей у больных сахарным диабетом типа 2. В кн.: Актуальные вопросы клинической эндокринологии. Ярославль: Рыбинский дом печати, 2004. С. 34-37.
3. Ross R, Fortier L, Hudson River. Specific association between inner and subcutaneous fat distribution, insulin and blood sugar levels in obese women. Treatment of Diabetes, 1996, 19:1404-11.
4. Bosi E, Camisasca RP, Collober C, Rochotte E, Garber AJEffects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin Diabetes Care, 2007, Apr, 30(4): 890-5.
Review
For citations:
Abayeva MS. Effect of hypoglycemic therapy on fat metabolism. Meditsinskiy sovet = Medical Council. 2014;(4):40-43. (In Russ.)
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