Effect of vitamin D on women’s somatic and reproductive health
https://doi.org/10.21518/2079-701X-2019-21-268-273
Abstract
The article presents the results of a study of the effect of vitamin D deficiency on women’s health.
The study aimed to determine the prevalence of vitamin D deficiency and its relationship with the somatic and reproductive health of women.
Methods: observation group I included 31 women with a reduced serum vitamin D levels (20.4 ± 1.0 ng/ml), comparison group II included 31 patients with normal vitamin D levels (39.0 ± 1.4 ng/ml). Results: the negative effect of vitamin D deficiency on women’s health is also practically assured, i.e. the incidence of somatic pathology is significantly higher in group I compared with group II: obesity (62.5 ± 12.1% and 18.8 ± 9.8%; p <0.5), insulin resistance (55.0 ± 9.0% and 1.0 ± 6.0%; p <0.001); arterial hypertension (42.0 ± 8.8% and 13.0 ± 6.0%; p <0.01); hypertrophic myocardiopathy (25.8 ± 7.8% and 6.4 ± 4.4%; p <0.05); chronic colitis (29.0 ± 8.1% and 6.4 ± 4.4%; p <0.05), gastric ulcer (22.5 ± 7.5% and 3.2 ± 3.2%; p <0.05), chronic pancreatitis (22.5 ± 7.5% and 3.2 ± 3.2%; p <0.05), chronic gastritis (25.8 ± 7.8% and 9.7 ± 5.3%; p <0.1). The interaction between reduced vitamin D levels and reproductive system diseases is confirmed by significant increase in the prevalence of secondary amenorrhea (80.0 ± 9.0% and 16.0 ± 7.3%; p <0.001), secondary oligomenorrhea (75.0 ± 9.7% and 20.0 ± 8.0%; p <0.001), hyperplastic processes – uterine fibroids (48.4 ± 9.0% and 13.3 ± 6.1%; p <0.001) and adenomyosis (26.6 ± 7.9% and 6.7 ± 4.5%; p <0.05), polycystic ovary syndrome (29.0 ± 8.2% and 6.7 ± 4.5%; p <0.05), vaginal microbiocenosis disorders (aerobic vaginitis – 42.0 ± 8.9% and 16.1 ± 6.6%; p <0.05; bacterial vaginosis – 29.0 ± 8.2% and 9.7 ± 5.3%; p <0.05).
Conclusion: management of vitamin D level is one of the priorities in the formation of therapeutic and preventive measures to improve the women’s health.
About the Authors
I. G. Zhoukovskaya
Izhevsk State Medical Academy
Russian Federation
Russian Federation
Inna G. Zhoukovskaya, Doctor of Medical Sciences, Associate Professor at the Departement of Obstetrics and Gynecology
281, Kommunarov St., Izhevsk, 426034, Russia
I. R. Yakupova
Izhevsk State Medical Academy
Russian Federation
Russian Federation
Ilvira R. Yakupova, a student
281, Kommunarov St., Izhevsk, 426034, Russia
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For citations:
Zhoukovskaya IG, Yakupova IR. Effect of vitamin D on women’s somatic and reproductive health. Meditsinskiy sovet = Medical Council. 2019;(21):268-273. (In Russ.) https://doi.org/10.21518/2079-701X-2019-21-268-273
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