Preview

Meditsinskiy sovet = Medical Council

Advanced search

Therapeutic and diagnostic approaches in the treatment of chronic tonsillitis

https://doi.org/10.21518/2079-701X-2022-16-20-90-99

Abstract

   Introduction. The relevance of the treatment of chronic tonsillitis is due to both the high prevalence and severity of the course of the disease with the variable development of tonsillogenic complications, both local and general. Important aspects are not always effective results of conservative methods of treatment, including the use of antibacterial drugs and, as a result, a decrease in the quality of life of patients.
   Objective. Based on the dynamics of blood leukocyte indices and local signs of chronic tonsillitis, to determine the effectiveness of a course of treatment using an effective antimicrobial agent of plant origin in patients of various age groups.

   Materials and methods. A prospective study was conducted in 494 patients aged 8 to 58 years who were treated on an outpatient basis for more than two years. Depending on the form of the disease and ongoing therapy, patients were randomly divided into 4 subgroups.
   Results and discussion. Evaluation of the effectiveness of treatment in groups of patients was carried out according to the indices in the leukocyte formula. A decrease in the average values of the indices was verified in most patients, which manifested itself in the activation of the phagocytic process with an antimicrobial herbal preparation and made it possible to reduce the manifestations of local and systemic clinical symptoms of chronic tonsillitis.
   Conclusion. Based on an objective assessment of the manifestations of local symptoms of chronic tonsillitis and an analysis of the dynamics of leukocyte blood indices, the effectiveness of a course of treatment with the inclusion of an antimicrobial agent of plant origin in patients of various age groups was shown.

About the Authors

M. Yu. Korkmazov
South Ural State Medical University
Russian Federation

Musos Yu. Korkmazov, Dr. Sci. (Med.), Professor, Head of the Department

Department of Otorhinolaryngology

454092

64, Vorovskiy St.

Chelyabinsk



A. P. Yastremsky
Tyumen State Medical University
Russian Federation

Andrey P. Yastremsky, Dr. Sci. (Med.), Professor

Department of Otorhinolaryngology

625023

54, Odesskaya St.

Tyumen



N. V. Kornova
South Ural State Medical University
Russian Federation

Natalia V. Kornova, Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department

Department of Otorhinolaryngology

454092

64, Vorovskiy St.

Chelyabinsk



M. A. Lengina
South Ural State Medical University
Russian Federation

Maria A. Lengina, Cand. Sci. (Med.), Associate Professor

Department of Otorhinolaryngology

454092

64, Vorovskiy St.

Chelyabinsk



A. M. Korkmazov
South Ural State Medical University
Russian Federation

Arsen M. Korkmazov, Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department

Department of Otorhinolaryngology

454092

64, Vorovskiy St.

Chelyabinsk



References

1. Pluzhnikov M. S. Angina and chronic tonsillitis. St Petersburg: Dialog; 2003. 151 p. (In Russ.)

2. Palchun V. T., Luchikhin L. A., Kryukov A. I. Inflammatory diseases of the pharynx. Moscow: GEOTAR-Media; 2007. 288 p. (In Russ.) Available at: https://search.rsl.ru/ru/record/01003151938.

3. Shchetinin S. A., Gizinger O. A., Korkmazov M. Yu. Clinical manifestations and dysfunctions of the immune status in children with chronic adenoiditis and methods of their correction using ozone therapy. Russian Journal of Immunology. 2015; 9 (3-1): 255-257. (In Russ.) Available at: https://elibrary.ru/item.asp?id=27342348.

4. Kryukov A. I., Izotova G. N., Zakharova A. F. The problem of chronic tonsillitis at the present stage. Rossiiskaya Otorinolaringologiya. 2009; (S2): 93-97. (In Russ.) Available at: https://www.elibrary.ru/contents.asp?id=34055672.

5. Korkmazov A., Korkmazov M. Methods of correction of the functional infringements of phagocytes and local manifestations of oxidative stress in the multiple shell of the nose region with use of ultrasound cavitation. Russian Journal of Immunology. 2018; 12 (3): 325-328. (In Russ.) Available at: https://elibrary.ru/item.asp?id=37020756.

6. Preobrazhensky B. S., Popov G. N. Angina, chronic tonsillitis and associated general diseases. Moscow: Meditsina; 1970. 384 p. (In Russ.)

7. Yastremsky A. P., Izvin A. I., Sannikov A. G., Sokolovsky N. S., Zakharov S. D. Results of the comparison of expert systems for the diagnosis of acute diseases of the pharynx. Medical Doctor and Information Technology. 2016; (5): 15-25. (In Russ.) Available at: https://elibrary.ru/item.asp?id=27266522&ysclid=l59ox24iqg685353777.

8. Korkmazov M. Y. Chronic tonsillitis and analysis of physical methods of exposure. Vestnik Oto¬ Rino¬ Laringologii. 2006; (Suppl. 5): 299-300. (In Russ.) Available at: https://www.elibrary.ru/item.asp?id=36259420.

9. Yastremsky A. P., Dyukova I. A., Vorkushin A. I. Development of an expert system for the differential diagnosis of chronic diseases of the pharynx. Sibirskii vestnik meditsinskoi informatiki i informatizatsii zdravookhraneniya. 2018; (1-2): 33-36. (In Russ.) Available at: https://elibrary.ru/item.asp?id=37422232&ysclid=l59p2s5wzj583904420.

10. Palchun V. T., Gurov A. V., Aksenova A. V., Guseva O. A., Arzamazov S. G., Nabieva T. T. Modern approaches to the diagnosis of diseases associated with chronic tonsillitis. Vestnik Oto¬ Rino¬ Laringologii. 2013; (3): 21-24. (In Russ.) Available at: https://elibrary.ru/item.asp?id=20188807&ysclid=l59p3k3erj803512336.

11. Korkmazov M. Yu., Zyrianova K. S., Dubinets I. D., Kornova N. V. Optimization of the pedagogical process at the department of otorhinolaryngology. Vestnik Oto¬ Rino¬ Laringologii. 2014; (1): 82-85. (In Russ.) Available at: https://elibrary.ru/item.asp?id=21204693.

12. Palchun V. T. The development of the problem of chronic tonsillitis. Vestnik Oto¬ Rino¬ Laringologii. 2006; (6): 7-8. (In Russ.) Available at: https://www.mediasphera.ru/issues/vestnik-otorinolaringologii/2006/6.

13. Blotsky A. A., Antipenko V. V. Chronic tonsillitis. Blagoveshchensk; 2018. 207 p. (In Russ.) Available at: https://www.amursma.ru/upload/docs/monografii/Blockij_A.A._Xronicheskij_tonzillit_monografiya__A.A._Blockij,_V.V_Antipenko._–_Blagoveshhensk_FGBOU_Amurskaya_GMA,_2018._-_207_s._ill...pdf.

14. Kryukov A. I., Aksenova A. V., Shostak N. A., Briko N. I., Gurov A. V., Kleimenov D. A. et al. Features of clinical and laboratory indicators of the activity of streptococcal infection in tonsillar pathology. Vestnik Oto¬ Rino¬ Laringologii. 2013; (3): 17-20. (In Russ.) Available at: https://www.elibrary.ru/item.asp?id=20188806.

15. Gadzhimirzaev G. A. About some provisions of the problem of chronic tonsillitis. Vestnik Oto¬ Rino¬ Laringologii. 2010; (6): 34-35. (In Russ.) Available at: https://www.elibrary.ru/item.asp?id=18261044.

16. Lukovsky L. A. The current state of the tonsillar problem and the ways of its further study. In: Proceedings of the IV Congress of Otorhinolaryngologists. Kyiv; 1972, pp. 45-51. (In Russ.) Available at: https://search.rsl.ru/ru/record/01007480502?ysclid=l59pbkfr243572945.

17. Kryukov A. I., Tovmasyan A. S., Drabkina I. V. The ability of B-hemolytic streptococcal group A to form a biofilm and its role in chronic tonsillitis. Rossiiskaya Otorinolaringologiya. 2009; (Suppl. 2): 97-102. (In Russ.) Available at: https://www.elibrary.ru/contents.asp?id=34055672.

18. Kryukov A. I., Tavmosyan A. S., Drabkina I. V., Sukhina M. A., Zhukhovitskii V. G. The role of microflora in the etiology of chronic tonsillitis. Vestnik Oto Rino¬ Laringologii. 2010; (3): 4-6. (In Russ.) Available at: https://www.elibrary.ru/item.asp?id=22793150.

19. Korkmazov M. Yu., Dubinets I. D., Lengina M. A., Solodovnik A. V. Local concentrations of secretory immunoglobulin A in patients with adenoiditis, rhinosinusitis and exacerbation of chronic suppurative otitis media against the background of the use of physical methods in complex therapy. Russian Journal of Immunology. 2021; 24 (2): 297-304. (In Russ.) https://doi.org/10.46235/1028-7221-999-LCO.

20. Dubinets I. D., Sinitskiy A. I., Korkmazov M. Yu., Chernykh E. I., Kukhtik S. Yu. Oxidative modification of proteins of the temporal bone tissue in chronic otitis media. Kazan Medical Journal. 2019; 100 (2): 226-231. (In Russ.) https://doi.org/10.17816/KMJ2019-226.

21. Dubinets I. D. Classification criteria for the primary diagnosis of chronic suppurative otitis media. Medical Journal of the Russian Federation. 2020; 26 (6): 431-438. (In Russ.) URL: https://medjrf.com/0869-2106/article/view/65043/ru_RU#!.

22. Korkmazov M. Yu., Kryukov A. I., Dubinets I. D., Tyukhai M. V., Uchaev D. A., Markelov A. V. Classification of structural changes in bone tissue in chronic purulent otitis media. Vestnik Oto¬ Rino¬ Laringologii. 2019; 84 (1): 12-17. (In Russ.) Available at: https://doi.org/10.17116/otorino20198401112.

23. Dubinets I. D., Korkmazov M. Yu., Sinitskii A. I., Danshova E. I., Skirpichnikov I. N., Mokina M. V., Mirzagaliev D. M. Local and systemic oxidative stress in chronic suppurative otitis media. Meditsinskiy Sovet. 2021; (18): 148-156. (In Russ.) https://doi.org/10.21518/2079-701X-2021-18-148-156.

24. Dubinets I. D., Kurenkov E. L., Kofanov R. V. Influence of the nature of morphological changes in the mucous membrane of the middle ear on the course of reparative processes in the nontympanic membrane during reconstructive sanitizing surgery in patients with chronic otitis media. Vestnik Oto¬ Rino¬ Laringologii. 2007; (5): 11-14. (In Russ.) Available at: https://elibrary.ru/item.asp?id=9576230.

25. Korkmazov A. M., Dubinets I. D., Lengina M. A. Possibilities of topical antioxidant protection of operated cavities in practical otorhinolaryngology. Vestnik Oto¬ Rino¬ Laringologii. 2017; 82 (Suppl. 5): 14-15. (In Russ.) Available at: https://elibrary.ru/item.asp?id=32285713.

26. Artyushkin S. A., Yeremina N. V., Ryazantsev S. V., Karneyeva O. V., Kryukov A. I., Kunel′skaya N. L. et al. Chronic tonsillitis: clinical guidelines. Moscow: National Medical Association of Otorhinolaryngologists; 2021. (In Russ.) Available at: https://cr.minzdrav.gov.ru/recomend/683_1.

27. Palchun V. T., Gurov A. V., Aksenova A. V., Guseva O. A. Differential diagnosis of chronic tonsillitis according to the severity of tonsillogenic intoxication of the body. Vestnik Oto¬ Rino¬ Laringologii. 2015; (5): 8-13. (In Russ.) https://doi.org/10.17116/otorino20158058-13.

28. Korkmazov M. Yu., Lengina M. A., Korkmazov A. M. Biochemical parameters of the nature of oxidative stress depending on the postoperative therapy in patients who underwent intranasal surgical interventions. Vestnik Oto Rino¬ Laringologii. 2016; 81 (Suppl. 5): 33-35. (In Russ.) Available at: https://www.elibrary.ru/item.asp?id=27636512.

29. Korkmazov M. Yu., Solodovnik A. A., Korkmazov А. М., Lengina М. А. Рrospects for using herbal preparation in combination with physical methods in complex therapy of chronic adenoiditis. Meditsinskiy Sovet. 2021; (18): 19-27. (In Russ.) https://doi.org/10.21518/2079-701X-2021-18-19-27.

30. Palchun V. T., Polyakova T. S., Romanova O. N. Therapeutic and diagnostic approaches to the problem of chronic tonsillitis. Vestnik Oto¬ Rino Laringologii. 2001; (1): 4-7. (In Russ.) Available at: http://elib.fesmu.ru/elib/Article.aspx?id=55277&ysclid=l59q38ypmy429230916.

31. Pokhodko-Chudakova I. O., Kazakova Yu. M. Forecasting the course of purulent¬ inflammatory processes in the maxillofacial region: methodical manual. Minsk: Belarusian State Medical University; 2008. 28 p. (In Russ.) Available at: http://rep.bsmu.by/handle/BSMU/7074?show=full&ysclid=l59q073hqy641902712.

32. Speransky V. V., Dmitrieva I. I., Zarilova R. M. Immunological informativeness of the leukocytogram. Klinichescheskaya Laboratornaya Diagnostika. 1999; (12): 6-7. (In Russ.)

33. Vedernikova I. A., Karavaeva O. Yu. Evaluation of the effectiveness of the treatment of compensated forms of chronic tonsillitis using a magnetically controlled ointment. Rossiiskaya Otorinolaringologiya. 2010; (S1): 310-312. (In Russ.)

34. Palchun V. T. Classification and therapeutic tactics in chronic tonsillitis. Vestnik Oto¬ Rino¬ Laringologii. 2013; (3): 8-11. (In Russ.) Available at: https://elibrary.ru/item.asp?id=20188804&ysclid=l59pt5uqn5293527373.

35. Korkmazov M. Yu., Korkmazov A. M., Dubinets I. D., Smirnov A. A., Kornova N. V. Influence of Non- Drug Therapy on Rehabilitation Time and Skeet Shooting after Rhinosurgical Interventions. Human. Sport. Medicine. 2020; (Suppl. 1): 136-144. (In Russ.) https://doi.org/10.14529/hsm20s117.

36. Talibov A. Kh., Korkmazov M. Yu., Lengina M. A., Krivopalov A. A., Grishaev N. V. Personalized Approach to Improving the Quality of Life and Psychophysical Readiness of Weightlifters Through the Correction of Sensory and Vasomotor Disorders of ENT Organs. Human. Sport. Medicine. 2021; 21 (4): 29-41. (In Russ.) URL: https://cyberleninka.ru/article/n/personifitsirovannyy-podhod-k-povysheniyu-kachestva-zhizni-i-psihofizicheskoy-gotovnosti-sportsmenov-girevikov-korrektsiey.

37. Dubinets I. D., Korkmazov M. Yu., Sinitskiy A. I., Uchaev D. A., Angelovich M. S. Changes in the elemental composition of the temporal bone in patients with chronic suppurative otitis media. Vestnik Oto¬ Rino¬ Laringologii. 2020; 85 (5): 44-50. (In Russ.) https://doi.org/10.17116/otorino20208505144.

38. Korkmazov M. Y., Langina M. A., Dubinets I. D., Korkmazov A. M., Smirnov A. A. Possibilities of correction of individual links of pathogenesis of allergic rhinitis and bronchial asthma with assessment of the quality of life of patients. Meditsinskiy Sovet. 2022; (16): 24-34. Available at: https://elibrary.ru/item.asp?id=48212495.

39. Svistushkin V. M., Nikiforova G. N., Toporkova L. A. The place of modern drugs with targeted action in the treatment of patients with tonsillar pathology. Meditsinskiy Sovet. 2018; (8): 36-40. (In Russ.) https://doi.org/10.21518/2079-701X-2018-8-36-40.

40. Kryukov A. I., Zhukhovitsky V. G., Tavmasyan A. S. Microbiological parameters in predicting the course of chronic tonsillitis. In: Materials of the I St Petersburg Forum of Otorhinolaryngologists of Russia. St Petersburg; 2012, pp. 334-335. (In Russ.)

41. Palchun V. T., Lapchenko A. S., Latenko A. A., Gurov A. V., Kucherov A. G. Modern view on antimicrobial photodynamic therapy. Vestnik Oto¬ Rino Laringologii. 2007; (3): 4-6. (In Russ.) Available at: https://elibrary.ru/item.asp?id=9511873&ysclid=l59plwrkne608830634.

42. Anjos L. M., Marcondes M. B., Lima M. F., Mondelli A. L., Okoshi M. P. Streptococcal acute pharyngitis. Rev Soc Bras Med Trop. 2014; 47 (4): 409-413. https://doi.org/10.1590/0037-8682-0265-2013.

43. Goldenzon R. V., Lucas T. O., Roiseman M. M. L., Rodrigues M. C. F., Fonseca A. R., Oliveira S. K. F., Goldenzon A. V. Valuing tonsillitis manifestations in school-children in Rio de Janeiro. Einstein (Sao Paulo). 2022; 20: eAO6342. Available at: https://pubmed.ncbi.nlm.nih.gov/35293435.

44. Sih T. M., Bricks L. F. Optimizing the management of the main acute infections in pediatric ORL: tonsillitis, sinusitis, otitis media. Braz J Otorhinolaryngol. 2008; 74 (5): 755-762. https://doi.org/10.1016/S1808-8694(15)31387-2.

45. Stelter K. Tonsillitis and sore throat in childhood. Laryngorhinootologie. 2014; 93 (Suppl. 1): 84-102. https://doi.org/10.1055/s-0033-1363210.

46. van Driel M. L., De Sutter A. I., Thorning S., Christiaens T. Different antibiotic treatments for group A streptococcal pharyngitis. Cochrane Database Syst Rev. 2021; 3 (3): CD004406. https://doi.org/10.1002/14651858.CD004406.pub5.


Review

For citations:


Korkmazov MY, Yastremsky AP, Kornova NV, Lengina MA, Korkmazov AM. Therapeutic and diagnostic approaches in the treatment of chronic tonsillitis. Meditsinskiy sovet = Medical Council. 2022;(20):90-99. (In Russ.) https://doi.org/10.21518/2079-701X-2022-16-20-90-99

Views: 478


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)