Preview

Meditsinskiy sovet = Medical Council

Advanced search

A modern view on the differential diagnosis of ultrasound characteristics of lymph nodes in mesadenitis in children

https://doi.org/10.21518/ms2023-269

Abstract

Mesadenitis (mesenteric lymphadenitis, mesenteritis) is a common cause of acute abdominal pain syndrome in children. At the same time, the cause of acute mesadenitis is far from being established in all cases. Diagnosis of mesenteric lymphadenitis presents a certain problem. Differential diagnosis is always carried out with acute surgical diseases of the abdominal cavity, primarily with acute appendicitis. Special attention is paid to ultrasound examination in the diagnosis of mesadenitis. Given the absence of statistically proven diagnostic criteria for changes in abdominal lymph nodes in mesadenitis, it is relevant to determine their ultrasound characteristics. The article is presented in the form of a lecture for practicing pediatricians based on a literature review. The characteristics of mesentery lymph nodes in various pathological processes are collected from various sources. The features of ultrasound characteristics of mesenteric lymph nodes in normal and acute mesadenitis with herpes infection, coronavirus infection, tuberculosis, as well as features of lymph nodes with lymphogranuloma are presented. A table has been developed that indicates such characteristics as the shape, number of lymph nodes in the section, echogenicity, blood flow status, capsule, contour, as well as additional characteristics in some conditions (such as the tendency to form conglomerates or the presence of calcinates in the structure of lymph nodes in tuberculosis lesions). A detailed description of the lymph nodes makes it possible to conduct a preliminary differential diagnosis of mesadenitis using ultrasound, which makes it possible to determine the vector of further diagnostic search in children with acute abdominal syndrome, and then to select pathogenetically justified therapeutic tactics and preventive measures.

About the Authors

S. S. Nikitin
Petrozavodsk State University; Children’s Republican Hospital named after I.N. Grigovich
Russian Federation

Sergei S. Nikitin, Dr. Sci. (Med.), Professor of the Center for Postgraduate Education of the Medical Institute, Petrozavodsk State University; Head of the Surgical Department and of the Center for Pediatric Urology, Andrology and Nephrol ogy, Children’s Republican Hospital named after I.N. Grigovich

33, Lenin Ave., Petrozavodsk, 185002, 

58, Parkovaya St., Petrozavodsk, 185002



N. B. Guseva
Pirogov Russian National Research Medical University; Children’s City Clinical Hospital No. 9 named after G.N. Speransky; Russian Medical Academy of Continuing Professional Education
Russian Federation

Natalia B. Guseva, Dr. Sci. (Med.), Head of the Moscow City Center of Pediatric Urology, Andrology and Pathology of Pelvic Organs, Children’s City Clinical Hospital No. 9 named after G.N. Speransky; Chief Researcher of the Department of Pediatric, Pirogov Russian National Research Medical University; Professor of the Department of Pediatric named after G.N. Speransky, Russian Medical Academy of Continuing Professional Education

29, Shmitovskiy Proezd, Moscow,123317, 

2, Taldomskaya St., Moscow, 125412,

28, Geroev Panfilovtsev St., Moscow, 125373



A. A. Kartseva
Petrozavodsk State University
Russian Federation

Alina A. Kartseva, Clinical Resident of the Department of Pediatrics and Pediatric Surgery of the Medical Institute

33, Lenin Ave., Petrozavodsk, 185002



M. V. Lepiseva
Children’s Republican Hospital named after I.N. Grigovich
Russian Federation

Mikhail V. Leukhin, Ultrasound Diagnostics Doctor

58, Parkovaya St., Petrozavodsk, 185002



I. V. Lepiseva
Children’s Republican Hospital named after I.N. Grigovich
Russian Federation

Inga V. Lepiseva, Chief Physician

58, Parkovaya St., Petrozavodsk, 185002



References

1. Кущ НЛ, Ткаченко ЛИ. Неспецифический мезентериальный лимфаденит у детей. Киев: Здоров’я; 1984. 80 с. Режим доступа: https://djvu.online/file/o8Yu5iMaeN1rH.

2. Sologub EA, Karaseva OV, Timofeeva AG. Nonspecific mesadenitis in children (literature review). Pediatric Pharmacology. 2013;10(1):18–25. (In Russ.) https://doi.org/10.15690/pf.v10i1.585.

3. Дёмина АМ, Новикова АА, Юрчук ЯС. Увеличение внутрибрюшных лимфатических узлов у детей по данным УЗИ органов брюшной полости. В: Проблемы и перспективы развития современной медицины: сборник научных статей XIII Республиканской научно-¬практической конференции с международным участием студентов и молодых ученых: в 9 томах. Гомель, 6–7 мая 2021 г. Гомель: ГомГМУ; 2021. Т. 5.

4. Жданов ДА. Общая анатомия и физиология лимфатической системы. Ленинград: Медгиз, Ленингр. отд-ние; 1952. 336 с.

5. Bardenikova SI, Shavlokhova LA, Shuvalov ME. Acute mesadenitis: a pediatrician’s view. RMJ. Medical Review. 2019;3(5):2–10 (In Russ.) Available at: https://www.rmj.ru/articles/khirurgiya/Ostryy_mezadenit_vzglyad_pediatra/.

6. Karmazyn B, Werner EA, Rejaie B, Applegate KE. Mesenteric lymph nodes in children: what is normal? Pediatr Radiol. 2005;3(88):774–777. https://doi.org/10.1007/s00247-005-1462-2.

7. Vakulenko MV, Anastasov AG, Haragezov AM, Strionova VS. Diagnostic and therapeutic management limphadenitis in children. University Clinic. 2017;(3-2): 20–22. (In Russ.) Available at: https://www.elibrary.ru/zwuiop.

8. Okuneva AI, Okunev NA, Kemaev AB, Soldatov OM. Mesadenitis in the structure of the acute abdomen in children. Russian Journal of Pediatric Surgery. 2019; 23(1S3):47. (In Russ.) Available at: https://www.elibrary.ru/pnrqzn.

9. Olkhova EB, Shchitinin VE. Abdominal pain syndrome in children: echographic variants. SonoAceIntern. 2004;(12):74–93. (In Russ.) Available at: https://www.medison.ru/si/art182.htm.

10. Olkhova EB, Shumeiko NK, Fomichev MYu. Mesadenitis in children with acute abdominal pain syndrome. Clinical and echographic parallels. Journal of Radiology and Nuclear Medicine. 2011;(3):45–48. (In Russ.) Available at: https://cyberleninka.ru/article/n/mezadenit-u-detey-c-ostrym-abdominalnymbolevym-sindromom-kliniko-ehograficheskie-paralleli-1/viewer

11. Timerbulatov VM, Fayazov RR, Sahautdinov RM, Timerbulatov ShV, Sagitov RB, Chanyshev BF. Acute mesenterial lymphadenitis in surgical practice. Annaly Khirurgii (Annals of Surgery, Russian Journal). 2009;(1):34–40 (In Russ.) Available at: https://www.elibrary.ru/kwsbhb.

12. Pykov MI, Sokolov YuYu, Balashov VV, Korovin SA. Ultrasonic evaluation of the state of abdominal lymph nodes in children normally and in acute abdominal syndrome. Children’s Hospital. 2013;(1):28–37. (In Russ.) Available at: https://www.elibrary.ru/sdylmv.

13. Fatkullina GR, Anokhin VA. Mesadenitis and herpetic infections. Russian Bulletin of Perinatology and Pediatrics. 2017;62(5):167–170. (In Russ.) https://doi.org/10.21508/1027-4065-2017-62-5-167-170.

14. Pykov MI, Sokolov YuYu, Balashov VV, Korovin SA. Ultrasound diagnostics of mesenteric lymphadenitis in children. Ultrasound and Functional Diagnostics. 2012;(6):49–55. (In Russ.) Available at: https://www.elibrary.ru/qbaaqv.

15. Jimenez DG, Rodriguez-Belvis MV, Gonzalez PF, Ortega GD, Segarra O, Benitez EM et al. COVID-19 gastrointestinal manifestations are independent predictors of PICU admission in hospitalized pediatric patients. Pediatr Infect Dis J. 2020;39(12):e459–e462. https://doi.org/0.1097/INF.0000000000002935.

16. Harwood R, Partridge R, Minford J, Almond S. Paediatric abdominal pain in the time of COVID-19: a new diagnostic dilemma. J Surg Case Rep. 2020;(9):rjaa337. https://doi.org/10.1093/jscr/rjaa337.

17. Noda S, Ma J, Romberg EK, Hernandez RE, Ferguson MR. Severe COVID-19 initially presenting as mesenteric adenopathy. Pediatr Radiol. 2021;51(1):140–143. https://doi.org/10.1007/s00247-020-04789-9.

18. Nikitin SS, Pyattoev YuG, Guseva NB, Leukhin MV, Vishnevskaya AV. Features of ultrasonic characteristics of mesenteric lymph nodes in COVID-19 in children with acute abdominal syndrome: description of clinical cases. Pediatriya – Zhurnal im G.N. Speranskogo. 2021;100(6):178–181. (In Russ.) https://doi.org/10.24110/0031-403X-2021-100-6-178-181.

19. Sorokina EV, Rudneva AE, Kostuchenko MV, Sorokina AA, Sokolova LV, Smirnova NV, Mizernitsky YuL. Hodzhkin’s lymphoma. Case reports from pediatric pulmonology. Zemskiy Vrach. 22012;(5):5–11. (In Russ.) Available at: https://www.elibrary.ru/petmxl

20. Elkov AYu, Fligil AE, Tarasova AA, Lazarev VV, Korsunsky AA. Role of Ultrasound in Children with Acute Intestinal Infections. Ultrasound and Functional Diagnostics. 2015;(1):72–80. Available at: https://vidar.ru/Article.asp?fid=USFD_2015_1_72.

21. Lee CC, Su CP, Chen SY, Chen S-C, Chen W-J. Mesenteric adenitis caused by Salmonella enterica serovar Enteritidis. J Formos Med Assoc. 2004;103(6): 463–466. Available at: https://pubmed.ncbi.nlm.nih.gov/15278192/.

22. Yarovaya YA, Lozovskaya ME, Pobezhimova YA, Vasilieva EB, Klochkova LV, Stepanov GA, Shibakova ND. Changes of abdominal organs in children with tuberculosis infection detected by ultrasound diagnostics. Pediatrician (St Petersburg). 2022;13(6):26–34. https://doi.org/10.17816/PED13626-34.

23. Lensky EV. Abdominal tuberculosis: difficulties in diagnosis. Siberian Medical Journal (Irkutsk). 22006;59(1):5–11. (In Russ.) Available at: https://www.elibrary.ru/jshzvj.

24. Ghazinoor S, Desser T, Jeffrey RB. Increased through-transmission in abdominal tuberculous lympadenitis. J Ultrasound Med. 2004;23(6):837–841. https://doi.org/10.7863/jum.2004.23.6.837.

25. Арямкина ОЛ, Савоненкова ЛН. Абдоминальный туберкулез: патоморфология, патогенез, классификация, клиника, диагностика. Ульяновск: УлГУ; 2010. 83 с. Режим доступа: https://www.ulsu.ru/media/documents/Абдоминальный_туберкулез.pdf


Review

For citations:


Nikitin SS, Guseva NB, Kartseva AA, Lepiseva MV, Lepiseva IV. A modern view on the differential diagnosis of ultrasound characteristics of lymph nodes in mesadenitis in children. Meditsinskiy sovet = Medical Council. 2023;(17):231-237. (In Russ.) https://doi.org/10.21518/ms2023-269

Views: 478


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)