Physicians’ knowledge and preferences regarding pharmacotherapy of pregnant women with respiratory tract infections: research PIKAP
R. A. Bontsevich,
A. A. Ryabchikova,
T. I. Balamutova,
O. V. Tsygankova,
O. G. Kompaniets,
G. G. Ketova,
V. O. Bogdanova,
G. A. Batisheva,
V. A. Nevzorova,
I. M. Martynenko,
N. A. Chukhareva,
S. P. Pakhomov,
M. L. Maximov https://doi.org/10.21518/ms2024-052
Abstract
Introduction. The most common extragenital pathology during pregnancy includes upper and lower respiratory tract infections (URTI and LRTI), which, if left untreated, leading to obstetric and perinatal pathology. It is relevant to conduct pharmacoepidemiological studies assessing the preferences of specialists regarding the treatment of pregnant women and attitudes towards vaccination in real clinical practice.
Aim. To analyze approaches to pharmacotherapy of URTI and LRTI in pregnant women, evaluate the compliance of prescribed drugs with current clinical recommendations and treatment standards.
Materials and methods. The study was conducted from 2018 to 2022 using an anonymous questionnaire method in seven regions of Russia.
Results and discussion. A total of 227 physicians from seven regions of Russia were surveyed, with 66.8% being internal medicine doctors and 33.2% obstetrician-gynecologists. This study revealed that physicians’ knowledge regarding the rational use of antimicrobial drugs (AMD) in pregnant women is insufficient. Respondents showed better results in the use of AMD in the treatment of pneumonia, with 78.7% of surveys indicating correct tactics. The worst results were observed in answering the question about the appropriateness of prescribing AMD for URTI, tracheitis, and bronchitis (40.3% to 67.7% of respondents made incorrect choices). Overall, 57.7% of respondents understand the importance of vaccination among pregnant women.
Conclusion. The results of the conducted study indicate that the choice of drugs for the therapy of URTI and LRTI, especially AMD, for outpatient treatment of pregnant women in some situations does not fully correspond to the current clinical recommendations in our country. Moreover, it is particularly concerning that some physicians prescribe drugs that are unsafe for pregnant women or lack the necessary evidence base or indications for use.
About the Authors
R. A. Bontsevich
Mari State University; Belgorod State National Research University; Kazan State Medical Academy – branch of the Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
Roman A. Bontsevich - Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department of Internal Diseases No. 2, Mari State University; Associate Professor of the Department of Pharmacology and Clinical Pharmacology, Belgorod State National Research University; Associate Professor of the Department of Clinical Pharmacology and Pharmacotherapy, Kazan State Medical Academy – branch of the Russian Medical Academy of Continuing Professional Education.
1, Lenin St., Yoshkar-Ola, Mari El Republic, 424000; 85, Pobedy St., Belgorod, 308015; 36, Butlerov St., Kazan, 420012
A. A. Ryabchikova
Belgorod State National Research University
Russian Federation
Russian Federation
Alina A. Ryabchikova - Student of the Medical Institute, Belgorod State National Research University.
85, Pobedy St., Belgorod, 308015
T. I. Balamutova
LLC Promedica
Russian Federation
Russian Federation
Tatiana I. Balamutova - Cardiologist, Therapist, LLC Promedica.
48a, Shchors St., Belgorod, 308036
O. V. Tsygankova
Novosibirsk State Medical University; Research Institute of Internal and Preventive Medicine, Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
Russian Federation
Russian Federation
Oksana V. Tsygankova - Dr. Sci. (Med.), Professor, Professor of the Department of Emergency Medicine with Endocrinology and Occupational Pathology of the Faculty of Continuing Education and Professional Retraining of Doctors, Novosibirsk State Medical University; Senior Researcher, Research Institute of Internal and Preventive Medicine, Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences.
52, Krasny Ave., Novosibirsk, 630091; 175/1, B. Bogatkov St., Novosibirsk, 630089
O. G. Kompaniets
Kuban State Medical University
Russian Federation
Russian Federation
Olga G. Kompaniets - Cand. Sci. (Med.), Chief Clinical Pharmacologist of Krasnodar City, Associated Professor of the Department of Therapy No. 1, Kuban State Medical University.
4, Sedin St., Krasnodar, 350063
G. G. Ketova
South Ural State Medical University
Russian Federation
Russian Federation
Galina G. Ketova - Dr. Sci. (Med.), Professor, Professor of the Department of Outpatient Therapy and Clinical Pharmacology, South Ural State Medical University.
64, Vorovskiy St., Chelyabinsk, 454092
V. O. Bogdanova
Endocrinology Research Centre; Russian Medical Academy of Continuous Professional Education
Russian Federation
Russian Federation
Valeriya O. Bogdanova - Cand. Sci. (Med.), Clinical Pharmacologist of the General Clinical Department, Endocrinology Research Centre; Associate Professor of the Department of Health Care Organization and Public Health with a course in Health Technology Assessment, Russian Medical Academy of Continuous Professional Education.
11, Dmitry Ulyanov St., Moscow, 117036; 2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993
G. A. Batisheva
Voronezh State Medical University named after N.N. Burdenko
Russian Federation
Russian Federation
Galina A. Batisheva - Dr. Sci. (Med.), Professor, Head of Department of Clinical Pharmacology, Voronezh State Medical University named after N.N. Burdenko.
10, Studencheskaya St., Voronezh, 394036
V. A. Nevzorova
Pacific State Medical University
Russian Federation
Russian Federation
Vera A. Nevzorova - Dr. Sci. (Med.), Professor, Head of the Institute of Therapy and Instrumental Diagnostic, Pacific State Medical University.
2, Ostriakov Ave., Vladivostok, 690002
I. M. Martynenko
Pacific State Medical University
Russian Federation
Russian Federation
Irina M. Martynenko - Cand. Sci. (Med.), Associate Professor, Institute of Therapy and Instrumental Diagnostics, Pacific State Medical University.
2, Ostriakov Ave., Vladivostok, 690002
N. A. Chukhareva
Fomin Women’s Health Clinic
Russian Federation
Russian Federation
Natalia A. Chukhareva - Cand. Sci. (Med.), General Practitioner, Fomin Women’s Health Clinic.
15a, Michurinsky Ave., Moscow, 119192
S. P. Pakhomov
Kursk State Medical University
Russian Federation
Russian Federation
Sergey P. Pakhomov - Dr. Sci. (Med.), Professor of the Department of Obstetrics and Gynecology, Kursk State Medical University.
3, Karl Marks St., Kursk, 305004
M. L. Maximov
Kazan State Medical Academy – branch of the Russian Medical Academy of Continuing Professional Education; Russian Medical Academy of Continuous Professional Education; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Maxim L. Maximov - Dr. Sci. (Med.), Professor, Head of the Department of Clinical Pharmacology and Pharmacotherapy, Kazan State Medical Academy – branch of the Russian Medical Academy of Continuing Professional Education; Professor of the Department of Pharmacology of the Institute of Pharmacy and Medical Chemistry, Pirogov Russian National Research Medical University; Dean of the Faculty of Preventive Medicine and Health Care Organization, Russian Medical Academy of Continuous Professional Education.
36, Butlerov St., Kazan, 420012; 1, Ostrovityanov St., Moscow, 117997; 2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993
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Review
For citations:
Bontsevich RA, Ryabchikova AA, Balamutova TI, Tsygankova OV, Kompaniets OG, Ketova GG, Bogdanova VO, Batisheva GA, Nevzorova VA, Martynenko IM, Chukhareva NA, Pakhomov SP, Maximov ML. Physicians’ knowledge and preferences regarding pharmacotherapy of pregnant women with respiratory tract infections: research PIKAP. Meditsinskiy sovet = Medical Council. 2024;(9):184-192. (In Russ.) https://doi.org/10.21518/ms2024-052
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