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A possible alternative to antibacterial therapy in the treatment of acute rhinosinusitis

https://doi.org/10.21518/ms2024-380

Abstract

High incidence of acute rhinosinusitis in a population remains one of the topical issues in practical otolaryngology. Statistical data show an increasing trend towards transition of acute rhinosinusitis in patients into chronic rhinosinusitis. According to literary sources, the emergence of bacterial resistance to antibiotics is as a rule the major reason of protracted course of the disease. Unreasonable antibiotics prescription, irrational use and uncontrolled intake result in the rapid development of antibiotic resistance. In this context, the use of herbal medicines having not only antibacterial, but also mucolytic, fungicidal, antioxidant effects in the complex therapy is a modern solution for disease management. Respero Myrtol, a standardized myrtol-based medicine, has taken its rightful place in the therapy. This article is aimed to investigate the possibilities of the effective use of medicine containing standardized myrtol as its main ingredient in the treatment of acute rhinosinusitis (based on the review of literature). Research materials included scientific articles on aspects of acute rhinosinusitis in otorhinolaryngology practice that were published in domestic specialized periodicals of eLIBRARY and scientific databases Scopus, Web of Science, Medline from 2014 to 2024. The published literature was analysed using the cause-and-effect technique. A clinical example was dis-cussed. With regard to the analysis of scientific literature, a brief overview of the epidemiology, etiology, predisposing factors for the development, diagnosis and treatment of acute rhinosinusitis was provided. The article addresses relevant socio-economic issues related to acute rhinosinusitis, the problem of antibiotic resistance. The issues of improving acute rhinosinusitis treatments using a standardized myrtol medicine in complex therapy as an alternative to antibiotic therapy were brought to attention. As a result, the authors concluded that the use of Respero Myrtol contributes to the rapid relief of clinical symptoms of acute rhinosinusitis, improves the patient’s quality of life, and can be advised as an alternative to antibiotic therapy in uncomplicated course of the disease.

About the Authors

A. A. Krivopalov
Saint Petersburg Research Institute of Ear, Throat, Nose and Speech; North-Western State Medical University named after I.I. Mechnikov
Russian Federation

Aleksandr A. Krivopalov - Dr. Sci. (Med.), Associate Professor, Head of the Department of Pathology of the Upper Respiratory Tract, Saint Petersburg RI of Ear, Throat, Nose and Speech; Associate Professor of the Department of Otorhinolaryngology, North-Western SMU named after I.I. Mechnikov;

9, Bronnitskaya St., St Petersburg, 190013; 41, Kirochnaya St., St Petersburg, 191015



S. V. Ryazantsev
Saint Petersburg Research Institute of Ear, Throat, Nose and Speech
Russian Federation

Sergey V. Ryazantsev - Dr. Sci. (Med.), Professor, Deputy Director for Scientific Work.

9, Bronnitskaya St., St Petersburg, 190013



V. I. Popadyuk
Peoples’ Friendship University of Russia named after Patrice Lumumba
Russian Federation

Valentin I. Popadyuk - Dr. Sci. (Med.), Professor, Dean of the Faculty of Continuing Medical Education, Head of the Department of Otorhinolaryngology of the Medical Institute.

6, Miklukho-Maklai St., Moscow, 117198



A. M. Korkmazov
South Ural State Medical University
Russian Federation

Arsen M. Korkmazov - Cand. Sci. (Med.), Associate Professor of the Department of Otorhinolaryngology.

454092, Russia, Chelyabinsk, Vorovskiy St., 64



A. A. Aslambekova
Saint Petersburg Research Institute of Ear, Throat, Nose and Speech
Russian Federation

Anzhela A. Aslambekova - Clinical Resident.

9, Bronnitskaya St., St Petersburg, 190013



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For citations:


Krivopalov AA, Ryazantsev SV, Popadyuk VI, Korkmazov AM, Aslambekova AA. A possible alternative to antibacterial therapy in the treatment of acute rhinosinusitis. Meditsinskiy sovet = Medical Council. 2024;(18):16-22. (In Russ.) https://doi.org/10.21518/ms2024-380

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