The role of second-generation antihistamines in treatment of allergic rhinitis
https://doi.org/10.21518/2079-701X-2013-3-16-19
Abstract
The article tells about the role of antihistamines (AHs) in the treatment of allergic rhinitis (AR). According to the modern trend, AHs are used in all forms of AR in adults and children as a monotherapy or in combination with other drugs, depending on the severity of the disease. Clinical effectiveness, high level of safety, lack of tachyphylaxis and ease of use make second-generation AH a drug of choice.
About the Authors
B. A. Chernyak
State Medical Academy of Postgraduate Studies, Irkutsk
Russian Federation
Russian Federation
I. I. Vorzheva
State Medical Academy of Postgraduate Studies, Irkutsk
Russian Federation
Russian Federation
References
1. ГЭОТАР-Медиа, 2009. – 656 с.
2. Астафьева Н.Г. Аллергический ринит и его влияние на астму: роль антигистаминных препаратов в лечении и профилактике // Рос. Аллергол. Жур. – 2008. – №1. – С. 37–48.
3. Гущин И.С. Спонтанная («конститутивная») активность и обратный агонизм на Н1-рецепторах // Рос. Аллергол. Жур. – 2006. – №2. – С. 3–14.
4. Гущин И.С. Разнообразие противоаллергического действия цетиризина // Рос. Аллергол. Жур. – 2006. – №4. – С. 33–44.
5. Горячкина Л.А., Передкова Е.В. Антигистаминные препараты в лечении аллергических заболеваний // Доктор. Ру – 2008. – №2 – С. 38–42.
6. Заболевания органов дыхания при беременности / Под ред. Чучалина А.Г., Фассахова Р.С. – М.: «Атмосфера», 2010. – 140 с.
7. Пампура А.Н. Антигистаминные препараты в лечении аллергических заболеваний у детей // Рос. Аллергол. Жур. – 2011. – №5. – С. 54–58.
8. Рациональная фармакотерапия аллергических заболеваний: руководство для практи-ческих врачей / Ред. Р.М. Хаитов, Н.И. Ильина, Т.В. Латышева Л.В. Л.У. Лусс – М.: ГЭОТАР-Медиа, 2007.– 504 с.
9. Черняк Б.А., Тяренкова С.В., Буйнова С.Н. Аллергические риниты в Восточной Сибири: распространенность, этиологическая характеристика, взаимосвязь с бронхи-альной астмой // Аллергология. – 2002. – № 2. С. 6–11
10. Черняк Б.А., Сергеева Е.К. Сравнительная оценка влияния дезлоратадина и флутиказона на неспецифическую назальную гиперреактвность при круглогодичном ал-лергическом рините // Аллергология. – 2006. – № 4. – С. 3–7.
11. Allergic rhinitis and its impact on asthma guidelines: 2010. Revision // J. Allergy Clin. Immunol. – 2010. – V. 126, №3. – P. 466–476.
12. Bachert C., Bousquet J., Canonica W., Durham S. et al. Levocetirizine improves quality of life and reduces costs in long-term management of persistent allergic rhinitis // J Allergy Clin Immunol. – 2004. – V. 114, №4 – P. 838–844.
13. Bousquet J., Khaltaev N., Cruz A.A. et al. Allergic rhinitis and its impact on asthma (ARIA) // Allergy. – 2008. – V. 63. – Suppl. 86. – P. 8–160.
14. Bruttmann G., Pedrali P., Arendt C., Rihoux J.P. Protective effect of cetirizine in patient suffering from pollen asthma // Ann. Allergy. – 1990. – V. 64, №2. – P. 224–228.
15. Canonica G.W., Fumagalli F.,Guerra L. et al. Levocetirizine in persistent allergic rhinitis: continuous or on-demand use? A pilot study // Current medical research and opinion. 2008. – V. 24, №10. – P. 2829–2839.
16. Ciprandi G., Cirillo I., Vizzaccaro A. et al. Desloratadine and levocetirizine improve nasal symptom, airflow, and allergic inflammation in patient with perennial allergic rhinitis: a pilot study // International Immunopharmacology. – 2005. – V. 5. – P. 1800–1808.
17. Cyr M.M., Hayes L.M., Crawford I. et al. The effect of desloratadine on eosinophil / basophil progenitors and other inflammatory markers in seasonal allergic rhinitis: a placebo-controlled randomized study // Int. Arch. Allergy Immunol. – 2005. – V. 38, №3. – P. 209–216.
18. Diepgen T.L. Early Treatment of the Atopic Child Study Group. Long-term treatment with cetirizine of infants with atopic dermatitis: a multi-country, double-blind, randomized, placebo-controlled trial (the ETAC trial) over 18 months // Pediatr Allergy Immunol.– 2002. – V. 13, №4. – P. 278–286.
19. Gillard M., Benedetti S.M., Chatelain P., Baltes E. Histamine H1-receptor occupancy and pharmacodynamics of second generation H1-antihistamines // Inflam Res. – 2005. – V. 54, №9. – P. 367–369.
20. Grant J.A., Nicodemus C.F., Findlay S.R. et аl. Cetirizine in patients with seasonal rhinitis and concomitant asthma: prospective, randomized, placebo-controlled trial // J Allergy Clin Immunol. – 1995. – V. 95, №5. – P. 923–932.
21. Mahmound F., Arifhodzic N., Haines D. Levocetirizine modulates lymphocyte activation in patient with allergic rhinitis // J Pharmacol. Sci.– 2008. – V. 108. – P. 149–156.
22. Mullol J., Roca-Ferrer J., Alobid I. et al. Effect of desloratadine on epitelial cell granulocyte-macrophage colony-stimulating factor secretion and eosinophil survival // Clin.Exp. Allergy. – 2006. – V. 36, №1. – P. 52–58.
23. Pradalier A., Neukirch C., Dreyfus I., Devillier P. Desloratadine improves quality of life and symptom severity in patient with allergic rhinitis // Allergy. – 2007. – V. 62, №11. – P. 1331–1334.
24. Simons F.E., Simons K.J. Clinical pharmacology of H1–antihistamines // Clin Allergy Immunol. – 2002. – V. 17. – Р. 141–178.
25. Tworek D., Bochenska-Marciniak M., Kupczyk M. The effect of 4 weeks treatment with desloratadine (5mg daily) on levels of interleukin IL-4, IL-10, IL-18 and TGF beta in patiens suffering from seasonal allergic rhinitis // Pulm Pharmacol Ther. – 2007. – V. 20, №3. – P. 244–249.
Review
For citations:
Chernyak BA, Vorzheva II. The role of second-generation antihistamines in treatment of allergic rhinitis. Meditsinskiy sovet = Medical Council. 2013;(3):16-19. (In Russ.) https://doi.org/10.21518/2079-701X-2013-3-16-19
Views:
515
Email this article 