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Low-carbohydrate diets in diabetes mellitus: A clinical case report and a brief literature review

https://doi.org/10.21518/ms2025-458

Abstract

Despite the numerous groups of hypoglycaemic drugs available, disability and mortality from complications of diabetes mellitus (DM) are increasing every year. This requires new effective approaches to the management of patients with DM. One of these approaches is diet therapy. Diet is considered the most important component of DM treatment by all authoritative organisations. Before the discovery of insulin, carbohydrate-restricted diets were widely used for DМ, but recently, leading publications have reported that dietary correction with carbohydrate restriction is required without clear guidelines on the extent of such restriction, and the focus is mainly on drug treatment. Analysis of the literature confirms the positive effect of low-carbohydrate diets (LCD) on weight loss, improvement of the glycaemic profile in DМ, and reducing the number and doses of hypoglycaemic drugs, but it remains unclear which diet to choose in a certain situation, which one will give the best results and be safe in the short and long term. Studies on this issue have been conducted, but their results are contradictory. To date, there is no consensus on which LCD diet is the optimal solution for DМ. The article describes a clinical case of four months treatment of LCD with moderate carbohydrate intake and its effect on weight, metabolic parameters, and hypoglycaemic therapy in a patient with long-term DM, corrected with insulin therapy for the last 10 years. This diet, combined with the patient’s high compliance, led to an 11-kilogram weight loss, improved carbohydrate metabolism and withdrawal from insulin therapy, as well as helped normalise blood pressure without the treatment of antihypertensive drugs and improved kidney function.

About the Authors

N. V. Khudyakova
College of Professional Studies – International Center of Professoinal Studies
Сербия

Natalia V. Khudyakova, Cand. Sci. (Med.), Professor

2, Cvječarska St., Novi Sad, 21000, Republic of Serbia



I. S. Khudiakov
PR “Natural Intelligence”
Сербия

Iurii S. Khudiakov, Cand. Sci. (Chem.), Psychologist, Director

9g, Lipovacka St., Vrnjachka Banya, 36210, Republic of Serbia



I. Yu. Pchelin
St Petersburg State University
Россия

Ivan Yu. Pchelin, Cand. Sci. (Med.), Associate Professor of the Department of Faculty Therapy

8а, 21st Liniya Vasilevskogo Ostrova St., St Petersburg, 199106, Russia



S. Stojanovich
College of Professional Studies – International Center of Professoinal Studies
Сербия

Srdjan Stojanovich, Dr. Sci. (Chem.), Professor, Head

2, Cvječarska St., Novi Sad, 21000, Republic of Serbia 



D. Radoičić
College of Professional Studies – International Center of Professoinal Studies
Сербия

Danijela Radoičić, Lecturer

2, Cvječarska St., Novi Sad, 21000, Republic of Serbia



N. Yu. Semigolovskii
St Petersburg State University
Россия

Nikita Yu. Semigolovskii, Dr. Sci. (Med.), Professor of the Department of Propaedeutics of Internal Diseases

8а, 21st Liniya Vasilevskogo Ostrova St., St Petersburg, 199106, Russia



S. O. Mazurenko
St Petersburg State University
Россия

Sergey O. Mazurenko, Dr. Sci. (Med.), Professor, Head of the Department of Propaedeutics of Internal Diseases

8а, 21st Liniya Vasilevskogo Ostrova St., St Petersburg, 199106, Russia



V. V. Smirnov
St Petersburg State Pediatric Medical University
Россия

Viktor V. Smirnov, Cand. Sci. (Med.), Associate Professor of the Department of Hospital Therapy with a Course of Endocrinology

2, Litovskaya St., St Petersburg, 194100, Russia



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For citations:


Khudyakova NV, Khudiakov IS, Pchelin IY, Stojanovich S, Radoičić D, Semigolovskii NY, Mazurenko SO, Smirnov VV. Low-carbohydrate diets in diabetes mellitus: A clinical case report and a brief literature review. Meditsinskiy sovet = Medical Council. 2025;(16):251–258. (In Russ.) https://doi.org/10.21518/ms2025-458

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