Oropharyngeal Dysphagia: Current diagnostic approaches
https://doi.org/10.21518/ms2026-313
Abstract
Swallowing disorders are frequent and cause increased mortality due to aspiration induced pneumonia, malnutrition and deterioration of quality of life. The demographic trend of development of society indicates a continuous increase of dysphagia in the future. Dysphagia occurs at any age, however, its prevalence increases with age. The causes of dysphagia in pediatrics and adolescence differ from those in middle age and senoirs. The main causes of oropharyngeal dysphagia include neurodegenerative and neurological diseases, tumors of the head and neck and the consequences of their treatment. Otorhinolaryngologists are often the first contact person patients turn to with problems of choking and coughing while eating. Diagnosis of swallowing is comlex, especially in cases of silent aspiration, when food enterst the lower respiratory tract without a cough reflex. Currenty, there is no common approach or algorithm for diagnosing oropharyngeal dysphagia. Questionnaires in many languages facilitate by collection of anamnesis and specific symptoms of dysphagia. Screening dysphagia tests allow rapid and cost-effective detection of dysphagia and determinate the necessity for further instrumental diagnostics. The gold standart of diagnostic for oropharyngeal dysphagia are the fiber-endoscopic evaluation of swallowing (FEES) and videofluoroscopy. Each of theese methods has its own advantages and limitations. Interdisciplinary collaboration with other specialists plays an important role not only in diagnosing of dysphagia, but also in planing of treatment, ensuring adequate nitrition and improving the quality of life of patients. The article reflects the main aspects of the physiology of the act of swallowing and modern diagnostic approach for the oropharyngeal dysphagia. The search for publication war carried out using the electronic databases of Google Scholar, PubMeb, eLIBRARY.RU, international and domestic journals.
About the Authors
E. S. MartinRussian Federation
Evgenia S. Martin, Junior Researcher, Scientific and Clinical Department of Laryngology
30, Bldg. 2, Volokolamskoe Shosse, Moscow, 123182
K. M. Magomedovа
Russian Federation
Kamila M. Magomedova, Cand. Sci. (Med.), Senior Researcher at Scientific and Clinical Department of Laryngology
30, Bldg. 2, Volokolamskoe Shosse, Moscow, 123182
T. I. Garashchenko
Russian Federation
Tatiana I. Garashchenko, Dr. Sci. (Med.), Professor, Chief Researcher, Scientific Secretary, The National Medical Research Center for Otorhinolaryngology of the Federal Medico-Biological Agency of Russia; Professor of the Department of Otorhinolaryngology, Pirogov Russian National Research Medical University
30, Bldg. 2, Volokolamskoe Shosse, Moscow, 123182,
1, Ostrovityanov St., Moscow, 117513
O. S. Orlova
Russian Federation
Olga S. Orlova, Dr. Sci. (Ped.), Professor, Chief Researcher at the Scientific and Clinical Department of Phoniatrics, The National Medical Research Center for Otorhinolaryngology of the Federal Medico-Biological Agency of Russia; Professor, Department of Logopedics, Institute of Childhood, Moscow Pedagogic State University; Chief Researcher, Federal Center of Brain Research and Neurotechnologies
30, Bldg. 2, Volokolamskoe Shosse, Moscow, 123182,
1, Bldg. 1, Malaya Pirogovskaya St., Moscow, 119991,
1, Bldg. 10, Ostrovityanov St., Moscow, 117513
I. I. Nazhmudinov
Russian Federation
Ismail I. Nazhmudinov, Student
4, Dolgorukovskaya St., Moscow, 127006
I. I. Nazhmudinov
Russian Federation
Ibragim I. Nazhmudinov, Dr. Sci. (Med.), Head of the Scientific and Clinical Department of Laryngology, The National Medical Research Center for Otorhinolaryngology of the Federal Medico-Biological Agency of Russia; Associate Professor of the Department of Otorhinolaryngology, Pirogov Russian National Research Medical University
30, Bldg. 2, Volokolamskoe Shosse, Moscow, 123182,
1, Ostrovityanov St., Moscow, 117513
References
1. Rommel N, Hamdy S. Oropharyngeal dysphagia: manifestation and diagnosis. Nat Rev Gastroenterol Hepatol. 2016;13(1):49–59. https://doi.org/10.1038/nrgastro.2015.199.
2. Pereverzev AP, Ostroumova OD, Tkacheva ON, Kochetkov AI. Drug-induced dysphagia in elderly patients. Russian Journal of Evidence-Based Gastroenterology. 2020;9(1):32–40. (In Russ.) https://doi.org/10.17116/dokgastro2020901132.
3. Leder SB, Suiter DM, Duffey D, Judson BL. Vokal fold immobility and aspiration status: a direct replication study. Dysphagia. 2012;27(2):265–270. https://doi.org/10.1007/s00455-011-9362-0.
4. Roden DF, Altman KW. Causes of dysphagia among different age group: a systematic review of the literature. Otolaryngol Clin North Am. 2013;46(6):965–987. https://doi.org/10.1016/j.otc.2013.08.008.
5. Baijens LW, Clave P, Cras P, Ekberg O, Foster A, Kolb GF et al. European Society of Swalloeing Disorders – European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome. Clin Interv Aging. 2016;11:1403–1428. https://doi.org/10.2147/CIA.S107750.
6. Kawashima K, Motohashi Y, Fujishima I. Prevalence of dysphagia among community-dwelling elderly individuals as estimated using a questionnaire for dysphagia screening. Dysphagia. 2004;19(4):266–271. https://doi.org/10.1007/s00455-004-0013-6.
7. Doan TN, Ho WC, Wang LH, Chang FC, Nhu NT, Chou LW. Prevalence and methods for assessment of oropharyngeal dysphagia in older adults: A systematic review and meta-analysis. J Clin Med. 2022;11(9):2605. https://doi.org/10.3390/jcm11092605.
8. Ivashkin VT, Mayev IV, Trukhmanov AS, Lapina TL, Sheptulin AA, Storonova OA, Andreev DN. Diagnostics and treatment of dysphagia: clinical guidelines ot the Russian gastroenterological association. Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2015;25(5):84–93. (In Russ.) Available at: https://www.gastro-j.ru/jour/article/view/1072/768.
9. Dodds WJ, Stewart ET, Logemann JA. Physiology and radiology of the normal oral and pharyngeal phases of swallowing. Am J Roentgenol. 1990;154(5):953–963. https://doi.org/10.2214/ajr.154.5.2108569.
10. Afkari S. Measuring frequency of spontaneous swallowing. Australas Phys Eng Sci Med. 2007;30(4):313–317. Available at: https://pubmed.ncbi.nlm.nih.gov/18274071.
11. Sato K, Nakashima T. Human adult deglutition during sleep. Ann Otol Laryngol. 2006;115(5):334–339. https://doi.org/10.1177/000348940611500503.
12. Logemann JA. Dysphagia: evaluation and treatment. Folia Phoniatr Logop. 1995;47(3):140–164. https://doi.org/10.1159/000266348.
13. Leopold NA, Kagel MC. Dysphagia – Ingestion or deglutition? A proposed paradigm. Dysphagia. 1997;12(4):202–206. https://doi.org/10.1007/PL00009537.
14. Maeda K, Ono T, Otsuka R, Ishiwata Y, Kuroda T, Ohyama K. Modulation of voluntary swallowing by visual input in humans. Dysphagia. 2004;19(1):1–6. https://doi.org/10.1007/s00455-003-0023-9.
15. Yosjikawa T, Tanaka M, Ishii A, Yamano Y, Watanabe Y. Visual food stimulus changes resting oscillatory brain activities related to appetitive motive. Behav Brain Funct. 2016:12(1):26. https://doi.org/10.1186/s12993-016-0110-3.
16. Tashiro N, Sugata H, Ikeda T, Matsushita K, Hara M, Kawakami K et al. Effects of individual food preferences on oscillatory brain activity. Brain Behav. 2019;9(5):e01262. https://doi.org/10.1002/brb3.1262.
17. Steele CM, Miller JA. Sensory input pathways and mechanisms in swallowing: A review. Dysphagia. 2010;25(4):323–333. https://doi.org/10.1007/s0045-010-9301-5.
18. Jestrovic I, Coyle JL, Sejdic E. Decoding human swallowing via electroencephalography: a state-of-the-art review. J Neural Eng. 2015;12(5):051001. https://doi.org/10.1088/1741-2560/12/5/051001.
19. Matsuo K, Palmer JB. Anatomy and Physiology of feeding and swallowing – normal and abnormal. Phys Med Rehabil Clin N Am. 2008;19(4):691–707. https://doi.org/10.1016/j.pmr.2008.06.001.
20. Ney DM, Weiss JM, Kind AJ, Robbins J. Senescent swallowing: impact, strategies, and interventions. Nutr Clin Pract. 2009;24(3):395–413. https://doi.org/10.1177/0884533609332005.
21. Schröter-Morasch H, Graf S. Dysphagiediagnostik durch den HNO-Arzt. HNO. 2014;62(5):324–334. https://doi.org/10.1007/s00106-014-2844-2.
22. Cheney DM, Siddiqui MT, Litts JK, Kuhn MA, Belafsky PC. The Ability of the 10-Items Eating Assessment Tool (EAT-10) to Predict Aspiration Risk in Person with Dysphagia. Ann Otol Rhinol Laryngol. 2015;124(5):351–354. https://doi.org/10.1177/0003489414558107.
23. Dwivedi RC, Rose S, Roe JW, Khan AS, Pepper C, Nutting CM, Kazi R. Validation of the Sydney Swallowing Questionnaire (SSQ) in a cohort of head and neck cancer patiens. Oral Oncol. 2010;46(4):e10–e14. https://doi.org/10.1016/j.oraloncology.2010.02.004.
24. Simons AJ, Firetzek UM, Waldman A, Warnecke T, Schuster T, Ceballos-Baumann AO. Development and validation oft he new screening questionnaire for dysphagia in early stages of Parkinson disease. Parkinsonism Relat Disord. 2014;20(9):992–998. https://doi.org/10.1016/j.parkreldis.2014.05.008.
25. Silbergleit AK, Schultz L, Jacobson BH, Beardsley T, Johnson AF. The Dysphagia handicap index: development and validation. Dysphagia. 2012;27(1):46–52. https://doi.org/10.1007/s00455-011-9336-2.
26. Chen AY, Frankowski R, Bishop-Leone J, Hebert T, Leyk S, Lewin J, Goepfert H. The developmert and validation of a dysphagia-specific quality-of-life questionnaire for patiens with head and neck cancer: the M.D. Anderson dysphagia inventory. Arch Otolaryngol Head Neck Surg. 2001;127(7):870–876. Available at: https://pubmed.ncbi.nlm.nih.gov/11448365.
27. McHorney CA, Bricker DE, Kramer AE, Rosenbek JC, Robbins J, Chignell KA, Clarke C. The SWAL-QOL outcomes tool for oropharyngeal dysphagia in adults: III. Documentation of reability and validity. Dysphagia. 2002;17(2):97–114. https://doi.org/10.1007/s00455-001-0109-1.
28. Garon BR, Sierzant T, Ormiston C. Silent aspiration: results of 2000 video fluoroscopic evaluations. J Neurosci Nurs. 2009;41(4):178–185. https://doi.org/10.1097/JNN.0b01e3181aaaade.
29. Daniels SK, Pathak S, Rosenbek JC, Morgan RO, Anderson JA. Rapid aspiration screening for suspectes stroke: Part 1: Development and validation. Arch Phys Med Reh. 2016;97(9):1440–1448. https://doi.org/10.1016/j.apmr.2016.03.025.
30. Fedder WN. Review of evidenced-based nursing protocols for dysphadia assessment. Stroke. 2017;48(4):e99–e101. https://doi.org/10.1161/SRTOKEAHA.116.011738.
31. Bours GJ, Speyer R, Lemmens J, Limburg M, de Wit R. Bedside screening tests vs. videofluoroscopy or fibreoptic endoscopic evaluation of swallowing to detect dysphagia in patients with neurological disorders: systematic review. J Adv Nurs. 2009;65(3):477–439. https://doi.org/10.1111/j.1365-2648.2008.04915.x.
32. Virvidaki IE, Nasios G, Kosmidou M, Giannopoulos S, Milionis H. Swallowing and aspiration risk: A critical review of non instrumental bedside screening test. J Clin Neurol. 2018;14(3):265–274. https://doi.org/10.3988/jcn.2018.14.3.265.
33. DePippo KL, Holas MA, Reding MJ. Validation oft he 3-oz water swallow test for aspiration following stroke. Arch Neurol. 1992;49(12):1259–1261. https://doi.org/10.1001/archneur.1992.00530360057018.
34. Suiter DM, Leder SB. Clinical utility of the 3-ounce water swallow test. Dysphagia. 2008;23(3):244–250. https://doi.org/10.1007/s00455-007-9127-y.
35. Leder SB, Suiter DM. Validation of the Yale Swallow Protocol: a prospective double-blinded videofluoroscopic study. Dysphagia. 2014;29(2):199–203. https://doi.org/10.1007/s00455-013-9488-3.
36. Trapl M, Enderle P, Nowotny M, Teuschl Y, Matz K, Dachenhausen A, Brainin M. Dysphagia bedside screening for acute stroke patients. The Gugging Swallowing Screen. Stroke. 2007;38(11):2948–2952. https://doi.org/10.1161/STROKEAHA.107.483933.
37. Sawashima M, Hirose H. New laryngoscopic technique by use of fiber optics. J Acount Soc Am. 1968;43(1):168–169. https://doi.org/10.1121/1.1910752.
38. Langmore SE. History of Fiberoptic Endoscopic Evaluation of Swallowing for Evaluation and Management of Pharyngeal Dysphagia: Changes over the Years. Dysphagia. 2017;32(1):27–38. https://doi.org/10.1007/s00455-016-9775-x.
39. Hey C, Pluschinski P, Pajunk R, Almahameed A, Girth L, Sader R et al. Penetration-aspiration: is their detection in FEES reliable without video recording? Dysphagia. 2015;30(4):418–422. https://doi.org/10.1007/s00455-015-9616-3.
40. Langmore S, Krisciunas G, Warner H, White SD, Dvorkin D, Fink D et al. Abnormalities of Aspiration and Swallowing Function in Survivors of Acute Respiratory Failure. Dysphagia. 2021;36(5):831–841. https://doi.org/10.1007/s00455-020-10199-8.
41. Suntrup-Krueger S, Scmidt S, Warnecke T, Steidl C, Muhle P, Schroeder JB et al. Extubation Readiness in Critically Ill Stroke Patients. Stroke. 2019;50(8):1981–1988. https://doi.org/10.1161/STROKEAHA.118.024643.
42. Schel R, Pisegna JM, McNally E, Noordzij JP, Langmore SE. Endoscopic Assessment of Swallowing After Prolonged Intubation in the ICU Setting. Ann of Otol, Rhinol and Laryngol. 2016;125(1):43–52. https://doi.org/10.1177/0003489415596755.
43. Zang J, Nienstedt JC, Kosek JC, Nießen A, Flügel T, Kim SH, Pflug C. Pediatric Flexible Endoscopic Evaluation of Swallowing: Critical Analysis of Implementation and Future Perspectives. Dysphagia. 2022;37(3):622–628. https://doi.org/10.1007/s00455-021-10312-5.
44. Reynolds J, Carroll S, Sturdivant C. Fiberoptic Endoscopic Evaluation of Swallowing: A Multidisciplinary Alternative for Assessment of Infants With Dysphagia in the Neonatal Intensive Care Unit. Adv Neonatal Care. 2016;16(1):37–43. https://doi.org/10.1097/ANC.0000000000000245.
45. Willette S, Hinkes Molinaro L, Thompson DM, Schroeder JWJr. Fiberoptic Examination of Swallowing in the Breastfeeding Infant. Laryngoscope. 2016;126(7):1681–1686. https://doi.org/10.1002/lary.25641.
46. Schumann-Werner B, Dogan I, Mirzazade S, Mall B, Overbeck R, Honrath P et al. Clinical predictors and neural correlates for compromised swallowing safety in Huntington disease. Eur J Neurol. 2021;28(9):2855–2862. https://doi.org/10.1111/ene.14953.
47. Rösler A, Pfeil S, Lessmann H, Höder J, Befahr A, von Renteln-Kruse W. Dysphagia in Dementia: Influence of Dementia Severety and Food Texture on the Prevalence of Aspiration and Latency to Swallow in Hospitalized Geriatric Patients. J Am Med Dir Assoc. 2015;16(8):697–701. https://doi.org/10.1016/j.jamda.2015.03.020.
48. Deutschmann MW, McDonough A, Dort JC, Dort E, Nakoneshny S, Matthews TW. Fiber-optic endoscopic evaliation of swallowing (FEES): Predictor of swallowing-related complications in the head and neck cancer population. Head Neck. 2013;35(7):974–979. https://doi.org/10.1002/hed.23066.
49. Neubauer PD, Hersey DP, Leder SB. Pharyngeal Residue Severity Rating Scales Based on Fiberopric Endoscopic Evaluation of Swallowing: A Systematic Review. Dysphagia. 2016;31(3):352–359. https://doi.org/10.1007/s00455-015-9682-6.
50. Rodrigues B, Nóbrega AC, Sampaio M, Argolo N, Melo A. Silent Saliva Aspiration in Parkinson`s Disease. Movement Disord. 2011;26(1):139–141. https://doi.org/10.1002/mds.23301.
51. Langmore SE. Evaluation of oropharyngeal dysphagia: which diagnostic tool is superior? Curr Opin Otolaryngol Head Neck Surg. 2003;11(6):485–489. https://doi.org/10.1097/00020840-2003120000-000014.
52. Ingleby HR, Bonilha HS, Steele CM. A Tutorial on Diagnostic Benefit and Radiation Risk in Videofluoroscopic Swallowing Studies. Dysphagia. 2023;38(2):517–542. https://doi.org/10.1007/s00455-021-10335-y.
53. Fujii N, Inamoto Y, Saitoh E, Baba M, Okada S, Yoshioka S et al. Evaluation of swallowing using 320-detector-row multislice CT. Part I: single- and multiphase volume scanning for three-dimensional morphological and kinematic analysis. Dysphagia. 2011;26(2):99–107. https://doi.org/10.1007/s00455-010-9276-2.
Review
For citations:
Martin ES, Magomedovа KM, Garashchenko TI, Orlova OS, Nazhmudinov II, Nazhmudinov II. Oropharyngeal Dysphagia: Current diagnostic approaches. Meditsinskiy sovet = Medical Council. 2026;(13):76-82. (In Russ.) https://doi.org/10.21518/ms2026-313
JATS XML

































