Questions of pathogenesis and treatment of post-stroke spasticity
https://doi.org/10.21518/2079-701X-2016-8-63-67
Abstract
Post-stroke spasticity considerably limits the ability to move for patients, hinders nursing, and contributes to the formation of pain syndromes. The article tells about the current understanding of the pathogenesis of cerebral spasticity, and discusses baseline treatment and rehabilitation activities. Administration of botulinum toxin type A for managing increased muscle tone in patients with stroke is considered in detail.
About the Authors
O. E. Zinovyeva
First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
V. A. Golovacheva
First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
References
1. Francisco GE, McGuire JR. Poststroke spasticity management. Stroke, 2012, 43(1): 3132-3136.
2. Ryu J, Lee J, Lee S et al. Factors predictive of spasticity and their effects on motor recovery and functional outcomes in stroke patients. Top Stroke Rehabil, 2010, 17: 380-8.
3. O'Dwyer N. J., Ada L., Neilson P.D. Spasticity and muscle contracture following stroke. Brain, 1996, 119: 1737-1749.
4. Pantano P, Formisano R, Ricci M et al. Motor recovery after stroke. Morphological and functional brain alterations. Brain, 1996, 119: 1849-1857.
5. Sommerfeld D, Eek E, Svensson A. Spasticity after stroke: its occurrence and association with motor impairments and activity limitations. Stroke, 2004, 35: 134-9.
6. Кадыков А.С., Шахпаронова Н.В. Спастичность как проблема двигательной реабилитации: роль миорелаксантов. Неврология и ревматология, 2014, 1: 56-59.
7. Blicher JU, Jakobsen J, Andersen G et al. Cortical excitability in chronic stroke and modulation by training: a TMS study. Neurorehabil. Neural. Repair., 2009, 23: 486-493.
8. Gracies J.M. Pathophysiology of spastic paresis. I: Paresis and soft tissue changes. Muscle Nerve, 2005, 31: 535-551.
9. Lotze M, Markert J, Sauseng P et al. The role of multiple contralesional motor areas for complex hand movements after internal capsular lesion. J. Neuroscience, 2006, 26: 6096-6102.
10. Завалишин И.А., Бархатова В.П. Спастичность. Журн. неврол. и психиатрии им. С.С. Корсакова, 1997, 97(3): 68-70.
11. Клюшников С.А., Иллариошкин С.Н., Иванова-Смоленская И.А. Спастический синдром в неврологии. Возможности толперизона (Мидокалма) в терапии спастических проявлений нейроваскулярных синдромов. Атмосфера. Нервные болезни, 2009, 3: 39-44.
12. Milanov I. Clinical and neurophysiological correlations of spasticity. Funct Neurol, 1999, 14: 193-201.
13. Huang CY, Wang CH, Hwang IS. Characterization of the mechanical and neural components of spastic hypertonia with modified H reflex. J Electromyogr Kinesiol., 2006, 16: 384-391.
14. Зиновьева О.Е., Катушкина Э.А., Яхно Н.Н., и др. Изменения скелетных мышц при постинсультной спастичности. Неврологический журнал, 2011, 4: 19-26.
15. Chardon MK, Suresh NL, Rymer WZ. An evaluation of passive properties of spastic muscles in hemiparetic stroke survivors. Conf Proc IEEE Eng Med Biol Soc, 2010, 2010: 2993-2996.
16. Ситнова М.А., Есин О.Р., Ресин РГ Постинсультная боль в области плеча: патогенез, принципы лечения. Практическая медицина, 2014, 2: 53-57.
17. Matsumoto S, Kawahira K, Etoh S еt al. Short-term effects of thermotherapy for spasticity on tibial nerve F-waves in post-stroke patients. Int. J. Biometeorol., 2006, 50(4): 243-250.
18. Thrasher TA, Popovic MR. Functional electrical stimulation of walking: function, exercise and rehabilitation. Annales de readaptation et de medecine physique, 2008, 51: 452-460.
19. Fink M, Rollnik JD, Bijak M et al. Needle acupuncture in chronic poststroke leg spasticity. Arch. Phys. Med. Rehabil., 2004, 85(4): 667-672.
20. Mohammad Y, Zahra G, Hanieh M et al. Comparing the efficacy of botulinum toxin with tizanidine in upper limb post stroke spasticity. Iranian journal of neurology, 2013, 12(2): 47-50.
21. Simon O, Yelnik AP Managing spasticity with drugs. European journal of physiology and rehabilitation medicine, 2010, 46(3): 401-410.
22. Yazdchi M, Ghasemi Z, Moshayedi H et al. Comparing the efficacy of botulinum toxin with tizanidine in upper limb post stroke spasticity. Iranian journal of neurology, 2013, 12(2): 47-50.
23. Grazko MA, Polo KB, Jabbari B. Botulinum toxin A for spasticity, muscle spasms, and rigidity. Neurology, 1995, 45: 712-717.
24. Rashear AB, Gordon MF, Elovic E et al. Intramuscular injection of botulinum toxin for the treatment of wrist and finger spastic-ity after a stroke. N. Engl. J. Med., 2002, 347: 395-400.
25. Yelnik AP, Colle FM, Bonan IV et al. Treatment of shoulder pain in spastic hemiplegia by reducing spasticity of the subscapular muscle: a randomised, double blind, placebo controlled study of botulinum toxin A. J. Neurol. Neurosurg. Psychiatry, 2007, 78: 845-848.
26. Cardoso E, Pedreira G, Prazeres A et al. Does botulinum toxin improve the function of the patient with spasticity after stroke? Arq. Neuropsiquiatr., 2007, 65(3-A): 592-595.
27. Парфенов В.А. Применение ботулинического токсина при постинсультной спастичности. Клиническая геронтология, 2001, 7(3-4): 46-49.
28. Bakheit AMO, Thilmann AF, Ward AB et al. A randomized, double-blind, placebo-controlled, dose ranging study to compare the efficacy and safety of three doses of Botulinum toxin type A (Dysport) with placebo in upper limb spasticity after stroke. Stroke, 2000, 31: 2402-2406.
29. Ward AB. Spasticity treatment with botulinum toxin. Turk J Med Rehab, 2007, 53(Suppl 2): 6-12.
30. Хатькова С.Е. Использование ботулотоксина (ботокс) при лечении больных с постинсультной спастичностью. Журн. неврология и психиатрия им. С.С. Корсакова, 2009, 109(6): 87-90.
31. Ward AB, Wissel J, Borg J et al. Functional goal achievement in post-stroke spasticity patients: The Botox Economic Spasticity Trial (BEST). J Rehabil Med, 2014, 46: 504-513.
32. Barnes MR. Management of spasticity. Age and Ageing, 1998, 27: 239-245.
Review
For citations:
Zinovyeva OE, Golovacheva VA. Questions of pathogenesis and treatment of post-stroke spasticity. Meditsinskiy sovet = Medical Council. 2016;(8):63-67. (In Russ.) https://doi.org/10.21518/2079-701X-2016-8-63-67
Views:
683
Email this article 