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Железодефицитная анемия во время беременности - профилактика и лечение

https://doi.org/10.21518/2079-701X-2015-9-78-83

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Аннотация

Данный обзор посвящен проблеме профилактики и лечения анемии во время беременности. Железодефицитная анемия (ЖДА) является самым распространенным дефицитным состоянием и наиболее частой формой анемии у беременных женщин. Клинические последствия ее крайне важны, т. к. неблагоприятные эффекты железодефицита не только затрагивают организм женщины, но и способны влиять на исходы беременности и здоровье новорожденных. Первая линия терапии железодефицита - это препараты железа, предназначенные для приема внутрь, наиболее эффективной и безопасной формой которых в настоящее время считается железо-полимальтозный комплекс. При недостаточной эффективности и тяжелой форме анемии предпочтительным альтернативным методом является внутривенное введение препарата железа. Своевременная диагностика и адекватная терапия позволяют в кратчайшие сроки восстановить показатели обмена железа у беременной женщины и не допустить развития осложнений.

Об авторах

М. А. Виноградова
Научный центр акушерства, гинекологии и перинатологии им. акад. В.И. Кулакова Минздрава России, Москва
Россия


Т. А. Фёдорова
Научный центр акушерства, гинекологии и перинатологии им. акад. В.И. Кулакова Минздрава России, Москва
Россия


Список литературы

1. WHO Iron Deficiency Anaemia: Assessment, Prevention and Control. WHO/NHD/01.3, World Health Organization, 2001, Geneva, Switzerland.

2. Sifakis S and Pharmakides G. Anemia in pregnancy. Ann. N. Y. Acad. Sci., 2000, 900: 125-36.

3. Ramsey M, James D & Steer P. Normal Values in Pregnancy, 2nd edn. WB Saunders, London, 2000.

4. Coad J, Conlon C. Iron deficiency in women: assessment, causes and consequences. Current opinion in clinical nutrition and metabolic care. 2011, 14, 625-634.

5. Friedman AJ et al. Iron deficiency anemia in women across the life span. Journal of women's health, 2012, 21: 1282-1289.

6. The Obstetric Hematology Manual edited by Sue Pavord, Beverley Hunt. Cambridge University Press 2010. P. 13-27.

7. Ren A, Wang J, Ye RW, Li S, Liu JM, Li Z (2007). Low first trimester hemoglobin and low birth weight, preterm birth and small for gestational age new-borns. Int J Gynaecol Obstet, 98: 124-128.

8. Koller O (1982). The clinical significance of hemodilution during pregnancy. Obstet Gynecol Surv, 37:649-652.

9. Breymann Ch et al. Diagnosis and treatment of iron-deficiency anaemia during pregnancy and postpartum. Arch Gynecol Obstet , 2010, 282: 577-580.

10. Milman N (2006). Iron and pregnancy - a delicate balance. Ann Hematol, 85: 559-565.

11. Bothwell TH (2000). Iron requirements in pregnancy and strategies to meet them. Am J Clin Nutr, 72: 257-264.

12. Milman N, Byg K-E, Ovesen L (2000). Iron status in Danes updated 1994. II. Prevalence of iron deficiency and iron overload on 1319 women aged 40-70 years. Influence of blood donation, alcohol intake, and iron supplementation. Ann Hematol, 79: 612-621.

13. Milman N. Prepartum anaemia: prevention and treatment. Ann Hematol, 2008, 87: 949-959.

14. Milman N (2006). Iron prophylaxis in pregnancy-general or individual and in which dose? Ann Hematol, 85: 821-828 doi:10.1007/ s00277-006-0145-x.

15. Milman N, Bergholdt T, Byg K-E, Eriksen L, Hvas A-M (2007). Reference intervals for haemato-logical variables during normal pregnancy and postpartum in 433 healthy Danish women. Eur J Haematol, 79: 39-46.

16. Makrides M, Crowther CA, Gibson RA, Gibson RS, Skeaff CM (2003). Efficacy and tolerability of low-dose iron supplements during pregnancy: a randomised controlled trial. Am J Clin Nutr, 78: 145-153.

17. Milman N, Bergholt T, Eriksen L, Byg K-E, Graudal N, Pedersen P, Hertz J (2005). Iron prophylaxis during pregnancy - how much iron is needed? A randomised, controlled study of 20 to 80 mg ferrous iron daily to pregnant women. Acta Obstet Gynecol Scand, 84: 238-247.

18. Skikne B, Baynes RD (1994). Iron absorption. In: Brock JH, Halliday JW, Pippard MJ, Powell LW (eds) Iron metabolism in health and disease. Saunders, London, pp 151-187.

19. Milman N, Graudal N, Nielsen OJ, Agger AO (1997). Serum erythropoietin during normal pregnancy: relationship to hemoglobin and iron status markers and impact of iron supplementation in a longitudinal, placebo-controlled study on 118 women. Int J Hematol, 66: 159-168.

20. Beris P, Maniatis A on behalf of the NATA working group on intravenous iron therapy (2007). Guidelines on intravenous iron supplementation in surgery and obstetrics/gynecology. TATM transfus Altern Transfus Med 9 (Suppl 1): 29.

21. Adamson JW. Fauci AS. Kasper Dl, et al. Iron deficiency and other hypoproliferative anaemias. In: Braunwald E, editor; Harrison's Principles of Internal Medicine.15th edition. Mc Graw Hill; 2001. pp 660-66.

22. Sharma N. Iron absorption: IPC therapy is superior to conventional iron salts. Obstet Gynecol., 2001: 515-19.

23. Toblli JE, Cao G, Oliveri L, Angerosa M. Effects of iron polymaltose complex, ferrous fumarate and ferrous sulfate treatments in anemic pregnant rats, their fetuses and placentas. Inflamm Allergy Drug Targets, 2013, 12(3): 190-8.

24. Badhwar VR, Rao S, Fonseca MM. Comparative efficacy and safety of iron polymaltose+folic acid and oral ferrous fumarate in the treatment of adult patients with iron deficiency anemia. Indian Med Gazette, 2003, 136: 296-301.

25. Patkar VD, Patkar S, Khandeparker PS, Dingankar NS, Shetty RS. Evaluation of efficacy and tolerability of iron (III) - hydroxide poly-maltose complex tablets in the treatment of iron deficiency anaemia in women. Indian Med Gazette, 2001, 135: 306-309.

26. Saha L, Pandhi P, Gopalan S, Malhotra S and Saha PK. Comparison of Efficacy, Tolerability, and Cost of Iron Polymaltose Complex With Ferrous Sulphate in the Treatment of Iron Deficiency Anemia in Pregnant Women. MedGenMed, 2007, 9(1): 1.

27. McCord JM. Iron, free radicals, and oxidative injury. Semin Hematol., 1998, 35: 5-12.

28. Christoph P, Schuller C, Studer H et al. Intravenous iron treatment in pregnancy: comparison of high-dose ferric carboxymaltose vs. iron sucrose. J Perinat Med, 2012, 13, 40(5), 469-474.

29. Reveiz L, Gyte GML, Cuervo LG, Casasbuenas A. Treatments for iron-deficiency anaemia in pregnancy (Review), Cochrane library, 2011.

30. Beris P, Maniatis A, on behalf of the NATA working group on intravenous iron therapy (2007) Guidelines on intravenous iron supplementation in surgery and obstetrics/gynecology. TATM transfus Altern Transfus Med 9 (Suppl 1): 29.


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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)