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Antihistamine therapy in pediatric practice

https://doi.org/10.21518/2079-701X-2018-11-136-139

Abstract

The article considers the role of histamine in the pathogenesis of allergic diseases and other pathological conditions. The mechanisms that contribute to the development of skin itching are considered separately. The article also shows the role and function of H1-histamine receptor blockers in the treatment of allergic diseases and pseudo allergic reactions. The mechanism of action, indications, contraindications and side effects of the antihistamine therapy are presented. The article also discusses the difference in first and second-generation antihistamines and shows the possible advantages of the first-generation drugs in paediatric practice. The article presents data on the use of dimethindene maleate (Fenistil) in children’s practice, including the use for the relief of skin itching of various genesis.

About the Author

S. V. Tsarev
National Research Centre Institute of Immunology, Federal Medical-Biological Agency of Russia, Moscow
Russian Federation


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Review

For citations:


Tsarev SV. Antihistamine therapy in pediatric practice. Meditsinskiy sovet = Medical Council. 2018;(11):136-139. (In Russ.) https://doi.org/10.21518/2079-701X-2018-11-136-139

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)