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5-Aminolevulinic acid photodynamic diagnosis of laryngeal papillomatosis

https://doi.org/10.21518/2079-701X-2019-11-195-199

Abstract

Photodynamic diagnosis is a promising method in the treatment of laryngeal papillomatosis, which includes an assessment of the increased visual and spectrometric contrast of papillomatosis masses against the background of the introduction of the photosensitizer. We have developed a method of treatment of laryngeal papillomatosis in two stages: intraoperative diagnosis using the domestic preparation of 5-aminolevulinic acid hydrochloride and subsequent surgical treatment using a carbon dioxide laser. Using the new method, we treated 21 patients, of which 13 (61.9%) had the inter-recurrent period longer than 12 months.

About the Authors

I. G. Guseinov
Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Moscow
Russian Federation

Guseinov Ismail Gasanovich – a postgraduate student

123182, Moscow, Volokolamskoe Shosse, 30, Bldg. 2



K. Sh. Davudov
Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Moscow
Russian Federation

Davudov Khasan Shakhmanovich – Dr. of Sci. (Med.), Professor, Deputy Director

123182, Moscow, Volokolamskoe Shosse, 30, Bldg. 2



T. I. Garashchenko
Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Moscow; Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of Russia
Russian Federation

Garashchenko Tatyana Ilynichna – Dr. of Sci. (Med.), Scientific Secretary, Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Russia; Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation

123182, Moscow, Volokolamskoe Shosse, 30, Bldg. 2, 

117997, Moscow, Ostrovityanova,1



I. I. Nazhmudinov
Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Moscow; Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of Russia
Russian Federation

Nazhmudinov Ibragim Ismailovich – Dr. of Sci. (Med.), Head of the Scientific Clinical Department of Upper Respiratory Diseases, Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Russia; Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation

123182, Moscow, Volokolamskoe Shosse, 30, Bldg. 2, 

117997, Moscow, Ostrovityanova,1



V. V. Vavin
Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Moscow
Russian Federation

Vavin Vyacheslav Valerievich – Cand. of Sci. (Med.), Otorhinolaryngologist

123182, Moscow, Volokolamskoe Shosse, 30, Bldg. 2



B. K. Davudova
Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Moscow
Russian Federation

Davudova Basharat Khasanovna – Cand. of Sci. (Med.), Senior Researcher

123182, Moscow, Volokolamskoe Shosse, 30, Bldg. 2



K. M. Magomedova
Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Moscow
Russian Federation

Magomedova Kamila Magomedovna – Cand. of Sci. (Med.), Otorhinolaryngologist

123182, Moscow, Volokolamskoe Shosse, 30, Bldg. 2



M. Yu. Khoranova
Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Moscow
Russian Federation

Khoranova Marina Yurievna – Junior Researcher

123182, Moscow, Volokolamskoe Shosse, 30, Bldg. 2



B. Z. Abdullaev
Federal State Budgetary Institution «Research and Clinical Center for Otorhinolaryngology» of the Federal Medical Biological Agency of Moscow
Russian Federation

Abdullaev Bashir Ziyavutdinovich – Junior Researcher

123182, Moscow, Volokolamskoe Shosse, 30, Bldg. 2



References

1. Filonenko E.V. Fluorescent diagnosis and photodynamic therapy in oncology. Extended abstract of Cand. Sci. (Eng.) Dissertation. Federal State Institute «Moscow Research Cancer Institute». Moscow, 2006 (In Russ).

2. Policard A. Etude sur les aspects offerts par des tumeurs experimentales examinees a la lumiere de Wood. C R Soc Biol 1924;91:1423-4.

3. Auler H, Banzer G. Untersuchungen ueber die Rolle der Porphyrine bei geschwulskranken Menschen und Tieren. Z Krebsforsch. 1942;53:65-8.

4. Figge H.J, Weiland GS, Manganiello LJ. Cancer detection and therapy, affinity of neoplastic, embryonic, and traumatized tissues for porphyrins and metalloporphyrins. Proc Soc Exp Boil Med. 1948;68:640-1.

5. Peck, G.C., H.P. Mack and W.A. Holbrook. Use of hematoporphyrin fluorescence in biliary and cancer surgery. Ann. Surg’. 1955;21:181-188.

6. Gray M.J., R.L Lipson, J.V.S. Maeck, L. Parker and D. Romeyn. (1967) Use of hematoporphyrin derivative in detection and management of cervical cancer: Am. Jv Obstet-Gynecor, 1999;766-77.

7. Leonard J.R. and W.L. Beck. Hematoporphyrin iluorescence: an aid to diagnosis of malignant neoplasms. Laryngoscope 81:365-372.

8. Profio A.E. and D.R. Doiron. Laser fluorescence bronchoscope for localization of occult lung tumours. Med. Phys. 6:523-525.

9. Hayata Y., H. Kato, C. Konaka, J. Ono, Y. Matsushima, K. Yoneyama and K. Nishimiya. Fiberoptic bronchoscopic laser photoradiation for tumor localization in lung cancer. Chest 1982;82:10-14.

10. Kennedy J.C., Pottier R.H., Pross D.C. Photodynamic therapy with endogenous protoporphyrin IX: Basic principles and present clinical experience. J. Photophem. Photobiol. 1990;6: 143-148.

11. Garashchenko T.I. Modern advances and further ways to improve the treatment of juvenile laryngeal papillomatosis in children. Proceedings of the 8th Congress of Paediatricians of Russia, M., 1998, p. 222-223 (In Russ).

12. Sokolov V.V. Combined endolaryngeal video endoscopic surgery and photodynamic therapy of patients with recurrent laryngeal and tracheal papillomatosis. Vestnik Otorinolaringologii. Ministry of Health of the Russian Federation, All-Russian Society of Otorhinolaryngologists, Yartek Medical LLP. 2007;6:4-9. (In Russ).

13. Tochner AZ, Pass Hi; Smith PD, DeLaney TF, Sprague M. DeLuca AM. et al. Intrathoracic photodynamic therapy: a canine normal tissue tolerance study and early clinical experience. Lasers Surg Med. 1994;14:118-23

14. Lightdale C.I, Heier SK, Marcon NE, McCoughan JS Jr., Gerdes H. Over-holt BF, et al. Photodynamic therapy with porfimer sodium versus thermal ablation therapy with Nd:YAG laser for palliation of esophageal cancer: a multicenter randomized trial, Gastromtest Endose 1995;42:507-12.


Review

For citations:


Guseinov IG, Davudov KS, Garashchenko TI, Nazhmudinov II, Vavin VV, Davudova BK, Magomedova KM, Khoranova MY, Abdullaev BZ. 5-Aminolevulinic acid photodynamic diagnosis of laryngeal papillomatosis. Meditsinskiy sovet = Medical Council. 2019;(11):195-199. (In Russ.) https://doi.org/10.21518/2079-701X-2019-11-195-199

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)