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Experience with Lavacol in the treatment of chronic constipation

https://doi.org/10.21518/2079-701X-2015-13-90-93

Abstract

The article tells about intermediate results of a comparative study of the efficacy and tolerability of Lavacol® in the treatment of chronic constipation. The treatment group consisted of patients receiving Lavacol®, and the control group included patients after treatment with Forlax. Comparison of findings obtained before treatment and within the same periods from the beginning of treatment, showed no significant difference between the groups. The results demonstrated high efficacy and safety of Lavacol® similar to that of Forlax for the symptomatic treatment of constipation in patients with functional constipation and constipation-predominant irritable bowel syndrome (in accordance with Rome III criteria).

About the Authors

V. G. Kukes
First Moscow State Medical University named after I.M. Sechenov, Moscow
Russian Federation


E. A. Smolyarchuk
First Moscow State Medical University named after I.M. Sechenov, Moscow
Russian Federation


S. Y. Serebrova
First Moscow State Medical University named after I.M. Sechenov, Moscow
Russian Federation


D. O. Kurguzova
First Moscow State Medical University named after I.M. Sechenov, Moscow
Russian Federation


References

1. D’Hoore A, Penninckx F. Obstructed defecation. Colorectal Dis, 2003. 5: 280-287.

2. Faigel OA. Clinical Approach to Constipation. Douglas Clin Cornerstone, 2002. 4(4): 11-21.

3. Drossman DA. The functional gastrointestinal disorders and the Rome III Process. Gastroenterology, 2006. 130(5): 1377-90.

4. Осадчук М.А., Бурдина В.О. Синдром раздраженного кишечника с внекишечными проявлениями с позиции нейроэндокринной патологии. Экспериментальная и клиническая гастроэнтерология, 2015. 2(114): 29-34.

5. Lacy BE, Loew B, Crowell MD. Prucalopride for chronic constipation. Drugs Today (Barc), 2009 Dec. 45(12): 43-53.

6. Dupont Ch, Leluyer B, Amar F et al. A dose determination study of polyethylene glycol 4000 in constipated children: factors influencing the maintenance dose. J Pediatr Gastroenterol Nutr, 2006. 42: 178-185.

7. Corazziari E, Badiali D, Bazzocchi G, et al. Long term efficacy, safety, and tolerability of low daily doses of isoosmotic polyethylene glycol electrolyte balanced solutio n (PMF-100) in the treatment of functional chronic constipation. Gut, 2000. 46: 522-526.

8. Chaussade S, Minic M. Comparison of efficacy and safety of two doses of two different polyethylene glycol-based laxatives in the treatment of constipation. Aliment Pharmacol Ther, 2003. 17: 165-172.

9. Костенко Н.В., Веселов В.В. Отечественный препарат полиэтиленгликоля в диагностике заболеваний толстой кишки. Фарматека, 2010. 20: 72-75


Review

For citations:


Kukes VG, Smolyarchuk EA, Serebrova SY, Kurguzova DO. Experience with Lavacol in the treatment of chronic constipation. Meditsinskiy sovet = Medical Council. 2015;(13):90-93. (In Russ.) https://doi.org/10.21518/2079-701X-2015-13-90-93

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)