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Diagnosis and treatment of Graves' disease

Abstract

Graves' disease (Basedow's goiter, exophtalmic goiter) is a systemic autoimmune disease resulting from the production of stimulating antibodies to the thyroid stimulating hormone (TSH) receptor; it is clinically manifested in lesions of the thyroid gland (TG) and thyrotoxicosis syndrome combined with extrathyroidal pathology (endocrine ophthalmopathy, pretibial myxedema, acropathy).

About the Author

V. V. Fadeyev
Head of the Department of Endocrinology, First Moscow State Medical University named after I.M.Sechenov
Russian Federation


References

1. Дедов И.И., Мельниченко ГА., Фадеев В.В. Эндокринология. М.: ГЭОТАР, 2007.

2. Barbesino G, Tomer Y. Clinical utility of TSH receptor antibodies. J. Clin. Endocrinol. Metab., 2013 Jun, 98(6): 2247-55.

3. Bartalena L. Diagnosis and management of Graves disease: a global overview. Nat Rev Endocrinol., 2013 Dec, 9(12): 724-34.


Review

For citations:


Fadeyev VV. Diagnosis and treatment of Graves' disease. Meditsinskiy sovet = Medical Council. 2014;(4):44-49. (In Russ.)

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)