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Клиническая эффективность и безопасность линаглиптина у пациентов с сахарным диабетом 2-го типа

https://doi.org/10.21518/2079-701X-2016-3-24-29

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Аннотация

Лечение сахарного диабета 2-го типа (СД2) - это серьезная проблема, заставляющая искать новые подходы к улучшению результатов фармакотерапии заболевания. Последние успехи в области диа-бетологии связаны с инкретин-направленной терапией. Наряду с традиционными дефектами (инсу-линорезистентность, дисфункция р-клеток), существенный вклад в развитие и прогрессирование заболевания вносит сниженный «эффект инкретинов». Концепция сниженного «эффекта инкрети-нов» послужила основанием для разработки и внедрения в клиническую практику инновационного направления - применение лекарственных средств, действие которых основано на «эффектах инкретинов», - глюкагоноподобного пептида-1 (ГПП-1) и глюкозозависимого инсулинотропного полипептида (ГИП) [12, 17].

Об авторах

Е. В. Бирюкова
Московский государственный медико-стоматологический университет им. А.И. Евдокимова
Россия


А. М. Мкртумян
Московский государственный медико-стоматологический университет им. А.И. Евдокимова
Россия


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ISSN 2079-701X (Print)
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