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Медицинский Совет

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Нарушения сна при мигрени

https://doi.org/10.21518/2079-701X-2021-2-111-120

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Аннотация

Мигрень и нарушения сна широко распространены среди населения, могут сочетаться друг с другом и зачастую значительно снижать качество жизни пациентов. Существование связи между мигренью и нарушениями сна на протяжении длительного времени подтверждалось клиницистами и данными эпидемиологических исследований. Тем не менее точная природа этой связи, лежащие в ее основе механизмы и закономерности сложны и не до конца изучены.
Представлены данные о коморбидности и взаимосвязи мигрени и нарушений сна: биохимические и функционально-анатомические предпосылки, взаимное влияние этих заболеваний друг на друга, а также типичные нарушения сна у пациентов с мигренью (инсомния, обструктивное апноэ сна, парасомнии, храп, повышенная дневная сонливость). Обсуждаются гипотезы патогенетической связи между этими состояниями на основе исследований анатомо-физиологических особенностей центральной нервной системы у людей с мигренью и нарушениями сна. Имеющиеся данные должны побудить врачей систематически оценивать качество сна у пациентов с мигренью и использовать комбинированные стратегии лечения. Рассмотрены как немедикаментозные, так и фармакологические методы лечения инсомнии; обсуждается преимущество комплексного подхода и предлагается краткий обзор каждой группы лекарственных средств.
Представлено описание клинического случая пациентки с хронической мигренью и инсомнией, которой проводилась комплексная терапия с применением доксиламина. Лечение доксиламином значительно снизило проявления инсомнии, что положительно повлияло на течение мигрени.

Об авторах

Н. В. Ващенко
Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет); Университетская клиника головной боли
Россия

Ващенко Нина Владимировна, аспирант, кафедра неврологии и нейрохирургии, Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет); невролог, Университетская клиника головной боли

119991, Москва, ул. Трубецкая, д. 8, стр. 2
121467, Москва, ул. Молодогвардейская, д. 2, корп. 1 



А. И. Кожев
Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)
Россия

Кожев Алексей Иванович, студент

119991, Москва, ул. Трубецкая, д. 8, стр. 2



Ю. Э. Азимова
Университетская клиника головной боли
Россия

Азимова Юлия Эдвардовна, к.м.н., невролог

121467, Москва, ул. Молодогвардейская, д. 2, корп. 1



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Для цитирования:


Ващенко Н.В., Кожев А.И., Азимова Ю.Э. Нарушения сна при мигрени. Медицинский Совет. 2021;(2):111-120. https://doi.org/10.21518/2079-701X-2021-2-111-120

For citation:


Vashchenko N.V., Kozhev A.I., Azimovа J.E. Sleep disorders in migraine. Meditsinskiy sovet = Medical Council. 2021;(2):111-120. (In Russ.) https://doi.org/10.21518/2079-701X-2021-2-111-120

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)