Optimization of the method for diagnostics of cardial autonomic neuropathy in diabetes mellitus 2 types
https://doi.org/10.21518/2079701X-2021-10-178-183
Abstract
Introduction. Early diagnosis of cardiac autonomic neuropathy is the basis for the risk of heart disease and premature death in patients with type 2 diabetes mellitus (type 2 diabetes). All patients with type 2 diabetes and prediabetes should undergo annual screening, including history taking and neurophysiologic evaluation, for early diabetic autonomic neuropathy. This article describes a modern diagnostic technique based on changes in heart rate variability, which allows early detection of damage to the parasympathetic nervous system and timely prescribing disease-modifying treatment in patients with type 2 diabetes.
Materials and methods. The study included 50 patients with type 2 diabetes (cf. Age 56.5 ± 13.5 years) and 30 healthy subjects (cf. Age 58 ± 10 years), matched by sex and age. according to the NSC questionnaire, the severity of neurological deficit - according to the NIS-LL scale, neuropathic pain syndrome - according to the TSS scale.
Results. In the study group of patients with type 2 diabetes, severe CAN was detected in 13.3%, moderate CAN in 40% of patients, in 46.6% of patients, CAN was not detected. In the group of healthy volunteers, disorders of the autonomic nervous system of moderate were detected in 3.3%, in the remaining 96.7% of autonomic disorders were not accepted.
Conclusion. The results of pulse oximetric tests with deep breathing are comparable to the results of the QAT device Case-4 (p < 0.001). The method of pulse oximetric diagnostics is more practical to use in comparison with the hardware QAT.
About the Authors
L. S. Moshkhoeva
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Lyuba S. Moshkhoeva, NeuroLogist, Postgraduate Student of the Department of Nervous Diseases and Neurosurgery.
8, BLdg. 2, Trubetskaya St., Moscow, 119991
A. N. Barinov
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Aleksey N. Barinov, Cand. Sci. (Med.), NeuroLogist, Associate Professor of the Department of Nervous Diseases and Neurosurgery.
8, BLdg. 2, Trubetskaya St., Moscow, 119991
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Review
For citations:
Moshkhoeva LS, Barinov AN. Optimization of the method for diagnostics of cardial autonomic neuropathy in diabetes mellitus 2 types. Meditsinskiy sovet = Medical Council. 2021;(10):178-183. (In Russ.) https://doi.org/10.21518/2079701X-2021-10-178-183
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