Legal framework for immunodiagnosis of tuberculosis in pediatric practice
https://doi.org/10.21518/ms2024-452
Abstract
Creation of a legal framework for immunodiagnosis of tuberculosis in paediatric practice in our country began in 1923, when the 2nd All-Russian Tuberculosis Congress and the 2nd All-Union Congress of Paediatricians were held. These congresses were known to approve the medicinal product label for the first tuberculosis diagnostic product Koch's alt-tuberculin. The product continued to improve; hence the method of tuberculin diagnosis has changed overtime. Starting from 2017, medical screening for TB in the paediatric population has been determined in Russia. TB is identified using various tuberculosis allergens according to the age group: a) immunodiagnostic examination of children aged 1–7 years is performed using a bacterial allergen with 2 tuberculin units of purified protein derivative-standard solution; b) immunodiagnostic examination of children aged 8–14 years is performed using the recombinant tuberculosis allergen derivative-standard solution; c) immunodiagnostic examination of children aged 15 through 17 years is performed using recombinant tuberculosis allergen derivative-standard solution or chest X-ray fluoroscopy. This review describes in detail the formation and development of the legal framework for screening for TB in the paediatric population in Russia. Detailed information on the current requirements for immunodiagnosis of TB in children and adolescents in accordance with the current legislation of the Russian Federation is presented. Issues of sanitary legislation, interdisciplinary interaction between primary health care facilities and anti-tuberculosis institutions are highlighted. Answers to the most frequently asked questions on the screening for TB in paediatric practice are provided.
About the Authors
L. A. Baryshnikova
Postnikov Samara Regional Clinical Tuberculosis Dispensary; Samara State Medical University; Kazan State Medical Academy – a branch of the Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
Lada A. Baryshnikova - Dr. Sci. (Med.), Deputy Chief Physician for Medical Affairs, Postnikov Samara Regional Clinical Tuberculosis Dispensary; Associate Professor of the Department of Pediatrics, IPE, Samara SMU; Associate Professor of the Department of Phthisiology and Pulmonology, Kazan State Medical Academy – a branch of the RMA of Continuing Professional Education.
154, Novo-Sadovaya St., Samara, 443068; 89, Chapaevskaya St., Samara, 443099; 11, Mushtari St., Kazan, 420012
D. A. Kudlay
Sechenov First Moscow State Medical University (Sechenov University); Lomonosov Moscow State University; National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia
Russian Federation
Russian Federation
Dmitry A. Kudlay - Corr. Member RAS, Dr. Sci. (Med.), Professor of the Department of Pharmacology, Institute of Pharmacy, Sechenov First MSMU (Sechenov University); Professor of the Department of Pharmacognosy and Industrial Pharmacy, Faculty of Fundamental Medicine, Lomonosov MSU; Leading Researcher of the Laboratory of Personalized Medicine and Molecular Immunology No. 71, NRC – Institute of Immunology Federal Medical-Biological Agency of Russia.
8, Bldg. 2, Trubetskaya St., Moscow, 119991; 1, Lenin Hills, Moscow, 119991; 24, Kashirskoye Shosse, Moscow, 115478
N. P. Doktorova
National Medical Research Center for Phthisiopulmonology and Infectious Diseases
Russian Federation
Russian Federation
Natalia P. Doktorova - Cand. Sci. (Med.), Researcher of the Scientific Department of Differential Diagnosis and Treatment of Tuberculosis and Comorbid Infections.
4, Bldg. 2, Dostoevsky St., Moscow, 127473
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For citations:
Baryshnikova LA, Kudlay DA, Doktorova NP. Legal framework for immunodiagnosis of tuberculosis in pediatric practice. Meditsinskiy sovet = Medical Council. 2024;(19):169-176. (In Russ.) https://doi.org/10.21518/ms2024-452
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