BRAFV600E-mutant colorectal cancer: A new approach to therapy
Abstract
The prevalence of colon and rectal cancer (colorectal cancer), one of the most commonly diagnosed malignant neoplasms with a high risk of metastasis and death, has been increasing steadily in Russia and throughout the world. Despite advances in the early diagnosis of the disease, there has been a constant increase in the number of patients with bowel cancer by 2% and about 75,000 new cases reported annually in this country over the past ten years. More than 90% of patients are people aged over 50 years, but recent years have witnessed a steady increase in the incidence of the disease among young patients. BRAF-mutated CRC follows an especially aggressive clinical course.
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BRAFV600E-mutant colorectal cancer: A new approach to therapy. Meditsinskiy sovet = Medical Council. 2025;(10):10-19. (In Russ.)
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