Features of seborrheic eczema with underlying herpes-viral infections

Seborrheic eczema is a chronic recurrent immune – mediated skin disease that significantly impairs the quality of life of patients. The pathogenesis of the development and course of SE is not completely clear. A proven fact related to the disease is an increase in the number of yeast-like fungi Malassezia spp. on the skin of patients in “seborrheic zones”. The growth of fungi Malassezia spp. It is associated with the level of secretion and changes in the composition of sebum, as well as with increased sweating in patients. But these changes are not sufficient for the formation of symptoms of seborrheic eczema. It has been established that in addition to the main links in the pathogenesis of SE, concomitant diseases can have a significant impact on it and lead to the fact that the clinical symptoms of SE become more manifest. For this reason, the aggravation of the symptoms of diabetes should lead a specialist to think about the combination of dermatosis with other diseases. The most common concomitant diseases are infectious processes, in particular herpetisvirus infections, which do not always have specific clinical symptoms. At the same time, the role of herpesvirus infections in the clinical manifestations of dermatosis has not been studied. Herpesvirus diseases are among the most common. So in 2020, there were about 570.1 million (13.5%) people infected with the herpes simplex virus type 2 worldwide, among patients aged 15 to 50 years. Herpes type 1 virus in the same age group and for the same period was detected in 395 million (10.5%) people. Of the total number of patients, 50% had exacerbations of concomitant diseases due to the presence of a viral infection. At the same time, it is a proven fact that herpesvirus infections significantly disrupt the functioning of the immune system, in particular, changes that trigger autoimmune processes. Thus, the severity of seborrheic eczema and the frequency of its exacerbations may indicate the presence of latent infections in the patient.

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