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Herbal remedies in the complex therapy of acute sinusitis in children of puberty

https://doi.org/10.21518/ms2025-406

Abstract

Introduction. The use of standardized medicines with multidirectional mechanisms of action, which correspond to phytoprepa­rations containing standardized myrtol, limonene, cineol and alpha-pinene, is of great importance in the treatment of acute sinusitis in puberty children.

Aim. To increase the effectiveness of conservative treatment of acute sinusitis in puberty patients using a phytopreparation with multidirectional mechanisms of action.

Materials and methods. A simple controlled clinical trial with randomization involved 36 patients with acute sinusitis aged 10 to 18 years on the background of acute respiratory infection. The clinical effectiveness of the use of a phytopreparation containing standardized myrtol in complex therapy relative to generally accepted treatment regimens was evaluated. The main objectives were to evaluate the safety of the drug, the effect on the recovery time and patient adherence. The severity of clinical manifestations of acute rhinosinusitis was studied using the SNOT-22 questionnaire. The effect of therapy on the quality of life of patients, cognitive functions, fatigue in school and other parameters were conducted using the SF-36 life questionnaire.

Results and discussion. Acute sinusitis in puberty patients with acute respiratory viral infection is more severe. This is due not only to aggressive infectious contamination of the mucous membranes, but also to the immunological resistance of adolescents in tran­sition. The use of a standardized myrtol-containing drug in the complex therapy of acute sinusitis has demonstrated better effective­ness in relieving symptoms of the disease, improving quality of life and school learning relative to conventional treatment regimens.

Conclusions. The clinical manifestations of acute sinusitis against the background of acute respiratory viral infection, due to the peculiarities of the restructuring of the body at puberty, differ in their variability. In stopping the cascade of symptoms of the disease, the standardized myrtol-containing drug Resper Myrtol has demonstrated greater effectiveness and safety relative to generally accepted regimens.

About the Authors

A. A. Krivopalov
Saint Petersburg Research Institute of Ear, Throat, Nose and Speech; North-Western State Medical University named after I.I. Mechnikov
Russian Federation

Aleksandr А. Krivopalov, Dr. Sci. (Med.), Head of the Research Department of Upper Respiratory Pathology of Saint Petersburg Research Institute of Ear, Throat, Nose and Speech; Associate Professor of the Department of ORL Diseases of the North-Western State Medical University named after I.I. Mechnikov

9, Bronnitskaya St., St Petersburg, 190013, 

41, Kirochnaya St., St Petersburg, 191015



N. V. Kornova
South Ural State Medical University
Russian Federation

Natalia V. Kornova, Cand. Sci. (Med.), Associate Professor, Associate Professor Department of Otorhinolaryngology

64, Vorovskiy St., Chelyabinsk, 454092



I. D. Dubinets
South Ural State Medical University
Russian Federation

Irina D. Dubinets, Cand. Sci. (Med.), Associate Professor, Associate Professor Department of Otorhinolaryngology

64, Vorovskiy St., Chelyabinsk, 454092



E. M. Lapushkin
Saint Petersburg Research Institute of Ear, Throat, Nose and Speech
Russian Federation

Evgenii M. Lapushkin, Otorhinolaryngologist, Postgraduate Student

9, Bronnitskaya St., St Petersburg, 190013



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Krivopalov AA, Kornova NV, Dubinets ID, Lapushkin EM. Herbal remedies in the complex therapy of acute sinusitis in children of puberty. Meditsinskiy sovet = Medical Council. 2025;(18):7-15. (In Russ.) https://doi.org/10.21518/ms2025-406

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