"Teaching and Research Medical Center" Federal State Institution of the Russian Federation Presidential Administration ARVI is a very widespread disease that requires a comprehensive approach to treatment, should be targeted at relieving clinical symptoms and meet current safety requirements to medicines. The market of combination drugs for the treatment of ARVI is represented by a variety of drugs for the symptomatic and pathogenetic therapy. AnviMax is the only drug with additional etiotropic action against viral agent which contains antiviral component rimantadine.

Acute respiratory viral infections (ARVI) are the most frequently occurring. Physicians of all specialities have to deal with ARVI in outpatient practice. In the present-day environment of the population migration, people concentration in metropolitan areas and active communication, viruses spread very easily and lead to unhealthy conditions. [7].

The article tells about clinical and diagnostic aspects of various forms of insomnia, and modern methods of treatment

The article tells about the pathogenetic mechanisms of action of triptans, principles of prescription and guidelines for relieving migraine.

The article is a brief overview of the recommendations of the American Gastroenterological Association in 2013 for diagnosis and treatment of gastroesophageal reflux disease (GERD).

The article tells about current issues in the treatment of chronic pancreatitis in adults. Particular attention is paid to the use of enzyme preparations as replacement and symptomatic therapy in chronic pancreatitis. There is a brief description of antispasmodics used for relief of abdominal pain in chronic pancreatitis.

Recent years have seen a revision of the traditional therapeutic approaches to many pathological conditions, which came as a result of the emergence of new data on the mechanisms of disease flow, original medicines and evidence-based clinical studies. Changes have affected many branches of medicine, including emergency.

The review presents data on the effectiveness of lipid profile correction with maximum doses of statins, primarily atorvastatin, and lipoprotein apheresis. The results of large-scale studies and meta-analyses evaluating the use of statins before and after coronary artery bypass surgery and stenting to reduce the risk of both early and late cardiovascular complications, and the need for revascularization of the myocardium, were analyzed. Lipid apheresis in patients with coronary artery disease who underwent coronary stenting or bypass surgery, and with hypercholesterolemia refractory to lipotropic therapy, is associated with reduced risk of in-stent restenosis, as well as destruction of bypass. Therefore, this method can be recommended to be used in patients with refractory hyperlipidemia undergoing myocardial revascularization.

The influence of combined antihypertensive therapy, including ACE inhibitor (ACEi) or Aliskiren, on the basic parameters of structural and functional state of the left ventricular (LV) myocardium in postmenopausal women with arterial hypertension (AH) and different types of obesity (abdominal and gluteofemoral) was evaluated.

Today we know that calcium and vitamin D are the essential factors of health of the whole organism. A balanced intake of calcium and vitamin D is a basis for the formation and maintenance of healthy bone, while their insufficiency is a risk factor for osteoporosis and fractures.

The relevance of hypothyroidism in clinical practice of doctor of any specialty causes no doubt. Hypothyroidism is one of the most frequent diseases of the endocrine system. According to some epidemiological studies, in specific population groups the prevalence of subclinical hypothyroidism reaches 1012% [6, 13, 16]. The last decade saw a number of new papers devoted to the problem of hypothyroidism, which transformed our idea of the entire thyroid pathology. This is primarily conditioned by the introduction of new thyroid hormone medications into clinical practice Indeed, for the patient, against a background of hardly a burdensome intake of drugs, hypothyroidism, in fact, ceases to be a disease and turns into a way of life with virtually no special restrictions. In the modern world hypothyroidism is no longer considered to be a complication of surgical treatment for Graves' disease (diffuse toxic goiter) and I therapy131, but became their goal. At the same time, hypothyroidism remains the only irrefutable and vital indication for prescribing thyroid hormones.

The main goal of diabetes therapy is to achieve normal or near normal levels of blood sugar, timely diagnosis, prevention and treatment of late complications of the disease which results in a decrease in the working ability, deterioration in the quality of life of patients, early disability and increased mortality.

Inflammatory diseases occupy leading positions in the list of gynaecological pathology. Inflammatory diseases of the pelvic organs (PID) recorded in 60-65% of women of reproductive age have a very negative impact on the female reproductive function, and cause chronic pelvic pain syndrome in 24% cases, infertility in 40%, miscarriage in 45%, and ectopic pregnancy in 3% of cases [1-3, 5, 7-9, 12, 13, 15-17, 20, 23]. Among inflammatory diseases in gynecology, endometritis and cervicitis account for about 70-80% of cases; however, the asymptomatic nature of the majority of endometritis and cervicitis cases (chronicity of the inflammatory process) and the fact of their being diagnosed only at routine gynecological exams, lead us to suggest that their incidence is much higher [4, 6, 10, 11, 14, 18, 19, 21, 22].

Currently, for a number of cases of grade III-IV osteoarthritis of the ankle, the only possible intervention which helps to relieve pain, pathological condition of the limb and restores its support ability is arthrodesis of the joint [1]. Arthroplasty and prosthetics of the ankle, largely having purely cognitive and historical value, are not practically applied [2].

The ways of improvement of the myocardial perfusion and its systolic function in patients with CAD with various cellular technologies has been studied for over 10 years. There is evidence that fibroblasts and their growth factors play a key role in promoting pathological proliferative processes in endothelial and smooth muscle cells of vascular walls in hyperglycemia.

The recent progress in clinical microbiology and molecular genetics of microorganisms has greatly expanded our knowledge about the spectrum of opportunistic pathogens. This fact objectively justifies the results of clinical observations on the relationship between opportunistic infections of the vagina and adverse pregnancy outcomes for mother and fetus [1, 7]. However, rational etiotropic treatment of vaginal infections during pregnancy continues to be a challenge. Till present, the question of using antibacterial agents in pregnant women remains controversial [9]. Russian guidelines on the treatment of bacterial vaginosis and Candida vaginitis during pregnancy mainly recommend local therapy, preferably in the II and III trimester. Foreign guidelines focus on systemic effect as early as during the I trimester, while local therapy is optional.