TOPICAL MEDICINES IN THE TREATMENT OF ALLERGODERMATHOSIS
https://doi.org/10.21518/2079-701X-2017-20-166-170
Abstract
Skin lesions, increased transepidermal water loss, changes in pH in patients with allergodermathosis lead to a decrease in the protective mechanisms of the skin that makes individuals more susceptible to infections. The development of complications predefined the interest in improving topical therapy. The article presents a brief review of the literature data on high therapeutic activity and good tolerability of the topical drug Triderm. When compared with the original drug, the generics revealed differences in the structural and mechanical properties, which affects bioavailability. A comparison of therapeutic efficacy and tolerability has shown that Triderm is more effective, and comparable to Akriderm GK in terms of tolerability.
About the Author
I. V. Khamaganova
Pirogov Russian National Research Medical University.
Russian Federation
Russian Federation
MD, Prof.
Moscow.
References
1. Nutten S. Atopic dermatitis: global epidemiology and risk factors. Ann Nutr Metab, 2015, 66(Suppl 1): 8-16. doi: 10.1159/000370220.
2. Gough H, Grabenhenrich L, Reich A et al. Allergic multimorbidity of asthma, rhinitis and eczema over 20 years in the German birth cohort MAS. Pediatr Allergy Immunol, 2015 Aug, 26(5): 431-7. doi: 10.1111/pai.12410.
3. Lee KS, Oh IH, Choi SH, Rha YH. Analysis of Epidemiology and Risk Factors of Atopic Dermatitis in Korean Children and Adolescents from the 2010 Korean National Health and Nutrition Examination Survey. Biomed Res Int, 2017, 2017: 5142754. doi: 10.1155/2017/5142754.
4. Eriksson S, van der Plas MJA, Mörgelin M, Sonesson A. Antibacterial and antibiofilm effects of sodium hypochlorite against Staphylococcus aureus isolates derived from patients with atopic dermatitis. Br J Dermatol, 2017, 177(2): 513521. doi: 10.1111/bjd.15410. Epub 2017 Jul 3.
5. Totté J, de Wit J, Pardo L, Schuren F, van Doorn M, Pasmans S. Targeted anti-staphylococcal therapy with endolysins in atopic dermatitis and the effect on steroid use, disease severity and the microbiome: study protocol for a randomized controlled trial (MAAS trial). Trials, 2017, 18(1): 404. doi: 10.1186/s13063-017-2118-x.
6. Barnes TM, Greive KA. Use of bleach baths for the treatment of infected atopic eczema. Australas J Dermatol, 2013, 54(4): 251-8. doi: 10.1111/ajd.12015.
7. Eriksson S, van der Plas MJA, Mörgelin M, Sonesson A. Antibacterial and antibiofilm effects of sodium hypochlorite against Staphylococcus aureus isolates derived from patients with atopic dermatitis. Br J Dermatol, 2017, 177(2): 513-521. doi: 10.1111/bjd.15410.
8. Harris V, Smith SD. Lifting the biofilm lid on the antibacterial and antibiofilm effects of sodium hypochlorite against Staphylococcus aureus in atopic dermatitis. Br J Dermatol, 2017, 177(2): 347-348. doi: 10.1111/bjd.15692.
9. Totté J, de Wit J, Pardo L, Schuren F, van Doorn M, Pasmans S. Targeted anti-staphylococcal therapy with endolysins in atopic dermatitis and the effect on steroid use, disease severity and the microbiome: study protocol for a randomized controlled trial (MAAS trial ). Trials, 2017, 18(1): 404. doi: 10.1186/s13063-0172118-x.
10. Wang X, Shi XD, Li LF, Zhou P, Shen YW. Classification and possible bacterial infection in outpatients with eczema and dermatitis in China: A cross-sectional and multicenter study. Medicine (Baltimore), 2017, 96(35): e7955. doi: 10.1097/MD.0000000000007955.
11. Тамразова О.Б., Новосельцев М.В. Экзематозные поражения кистей рук. Вестник дерматологии и венерологии, 2016, 1: 85-92.
12. Кочергин Н.Г., Олисова О.Ю. Комбинированная наружная терапия при атопическом дерматите. Фарматека, 2017, S4: 44-49.
13. MacGillivray ME, Fiorillo L. An Unanticipated Complication of Atopic Dermatitis. Pediatr Emerg Care,. 2017 Apr 18. doi: 10.1097/ PEC.0000000000001105.
14. Metin A, Dilek N, Demirseven DD. Fungal infections of the folds (intertriginous areas). Clin Dermatol, 2015, 33(4): 437-47. doi: 10.1016/j.clindermatol.2015.04.005. Epub 2015 Apr 7.
15. Prohic A, Jovovic Sadikovic T, Krupalija- Fazlic M, Kuskunovic-Vlahovljak S. Malassezia species in healthy skin and in dermatological conditions. Int J Dermatol, 2016, 55(5): 494-504. doi: 10.1111/ijd.13116. Epub 2015 Dec 29.
16. Prohić A, Jovović Sadiković T, Kuskunović- Vlahovljak S, Baljić R. Distribution of Malassezia Species in Patients with Different Dermatological Disorders and Healthy Individuals. Acta Dermatovenerol Croat, 2016 Dec, 24(4): 274-281.
17. Соколова Т.В., Григорян С.А., Мокроносова М.А. Особенности течения и ведения больных микробной экземой, осложненной кандидозом. Российский журнал кожных и венерических болезней, 2007, 1: 13-20.
18. Львов А.Н. Пропедевтические основы комбинированной наружной терапии при дерматозах сочетанной этиологии. Клиническая дерматология и венерология, 2016, 1: 78-84.
19. Данилов С.И., Пирятинская В.А. Топические глюкокортикостероиды нового поколения в наружной терапии дерматозов. РМЖ, 2000, 6: 257.
20. Инструкция по применению препарата Тридерм (©Байер, последнее обновление 28 августа 2017).
21. Молохова Е.И., Сорокина Ю.В. Сравнительное изучение реологических характеристик оригинального препарата тридерм и его дженериков в форме крема. Антибиотики и химиотерапия, 2014, 5-6: 3-5.
22. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol. Suppl, 1980, 92: 44-47.
Review
For citations:
Khamaganova IV. TOPICAL MEDICINES IN THE TREATMENT OF ALLERGODERMATHOSIS. Meditsinskiy sovet = Medical Council. 2017;(20):166-170. (In Russ.) https://doi.org/10.21518/2079-701X-2017-20-166-170
Views:
777
Email this article 