The place of metoprolol tartrate in the treatment of cardiovascular diseases
https://doi.org/10.21518/2079-701X-2016-4-16-19
Abstract
Since the beginning of the 1960s, beta-blockers have been number one medications in the treatment of cardiovascular diseases. A number of randomized controlled trials (RCTs) demonstrated positive effect of beta-blockers on morbidity and mortality [1]. It is difficult to overestimate the role of beta-blockers in modern cardiology. According to the results of a meta-analysis of 18 RCTs, administration of beta-blockers in patients with a risk of cardiovascular disease was associated with a reduction of the risk of stroke by 29%, coronary heart disease (CHD) by 7%, and chronic heart failure (CHF) by 29% [2]. In combination with ACE inhibitors, antiplatelet agents and statins, beta blockers helped to decrease mortality from acute coronary syndrome by 90% [3].
About the Authors
N. V. Romanova
Research Institute of Cardiology named after A.L. Myasnikov; Russian Cardiology Research and Production Complex
Russian Federation
Russian Federation
I. V. Zhirov
Research Institute of Cardiology named after A.L. Myasnikov; Russian Cardiology Research and Production Complex
Russian Federation
Russian Federation
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Review
For citations:
Romanova NV, Zhirov IV. The place of metoprolol tartrate in the treatment of cardiovascular diseases. Meditsinskiy sovet = Medical Council. 2016;(4):16-19. (In Russ.) https://doi.org/10.21518/2079-701X-2016-4-16-19
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