Etiology, pathogenesis and diagnosis of chronic obstructive pulmonary disease: Assessment of the knowledge of doctors and senior students. Results of the ASCO-III study
R. A. Bontsevich,
G. I. Zavitkevich,
G. A. Batishcheva,
V. A. Nevzorova,
O. V. Tsygankova,
G. G. Ketova,
I. M. Martynenko,
I. F. Krotkova,
E. Yu. Ebzeeva,
G. M. Bikkinina,
I. K. Suvanov,
E. A. Shabanov,
G. G. Prozorova,
U. M. Tilekeeva,
O. G. Kompaniets,
E. N. Bochanova,
E. V. Luchinina,
M. L. Maximov https://doi.org/10.21518/ms2025-037
Abstract
Introduction. Chronic Obstructive Pulmonary Disease (COPD) is one of the leading causes of death in the world, being a global problem. In Russia, the prevalence of COPD is 15.3% in the general population and 21.8% among people with respiratory symptoms. Nevertheless, this disease is quite successfully treatable and controllable.
Aim. To determine the level of basic knowledge among therapeutic profile physicians and senior medical students regarding the issues of etiopathogenesis and diagnosis of COPD.
Materials and methods. The ASCO-III study was conducted in 2019–2023 using an anonymous questionnaire, 478 therapeutic doctors from 11 centers and 401 students from 7 centers participated in it. An original questionnaire based on current clinical recommendations was used to conduct the ASCO-III study.
Results. The study revealed an insufficient level of knowledge among doctors and students regarding the etiology, pathogenesis, and diagnosis of COPD. In the section on “Etiopathogenesis and Diagnostics,” the level of correct answers (LCA) among doctors was 73.5%, increasing to 82% when including questions about vaccination. For students, the LCA was 68% and 73.6%, respectively. Significant differences were observed between the overall populations of doctors and students concerning the final LCA (p < 0.001). The best results were noted in questions about risk factors for COPD, with 88.0% of doctors and 88.8% of students providing correct answers. Additionally, in questions regarding the signs that may suggest this disease, the correct answer rates were 89.9% for doctors and 84.9% for students. Conversely, the lowest scores were recorded for questions about the CAT and mMRC scales, with incorrect responses from 69.3% of doctors and 72.8% of students. Furthermore, in the question assessing the importance of vaccination as a means of controlling COPD, 45.5% of doctors and 61.6% of students provided incorrect answers.
Conclusions. During the analysis of the results of the study, an insufficient level of basic knowledge of respondents on COPD was revealed, which, according to the authors, indicates the need for additional educational activities among practicing doctors and students.
About the Authors
R. A. Bontsevich
Mari State University;
Belgorod State University;
Kazan State Medical Academy – a branch of the Russian Medical Academy of Continuing Professional Education
Russian Federation
Russian Federation
Roman A. Bontsevich, Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department of Internal Diseases No. 2, Mari State University; Associate Professor of the Department of Pharmacology and Clinical Pharmacology, Belgorod State National Research University; Associate Professor of the Department of Clinical Pharmacology and Pharmacotherapy, Kazan State Medical Academy – branch of the Russian Medical Academy of Continuing Professional Education
1, Lenin St., Yoshkar-Ola, Mari El Republic, 424000,
85, Pobedy St., Belgorod, 308015,
36, Butlerov St., Kazan, 420012
G. I. Zavitkevich
Mari State University
Russian Federation
Russian Federation
Georgy I. Zavitkevich, Student of the Medical Institute, Researcher of the Medical Scientific and Educational Center
1, Lenin St., Yoshkar-Ola, Mari El Republic, 424000
G. A. Batishcheva
Voronezh State Medical University named after N.N. Burdenko
Russian Federation
Russian Federation
Galina A. Batishcheva, Dr. Sci. (Med.), Professor, Head of Department of Clinical Pharmacology
10, Studencheskaya St., Voronezh, 394036
V. A. Nevzorova
Pacific State Medical University
Russian Federation
Russian Federation
Vera A. Nevzorova, Dr. Sci. (Med.), Professor, Head of the Institute of Therapy and Instrumental Diagnostic
2, Ostriakov Ave., Vladivostok, 690002
O. V. Tsygankova
Novosibirsk State Medical University;
Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
Russian Federation
Russian Federation
Oksana V. Tsygankova, Dr. Sci. (Med.), Professor, Professor of the Department of Emergency Medicine with Endocrinology and Occupational Pathology of the Faculty of Continuing Education and Professional Retraining of Doctors, Novosibirsk State Medical University; Senior Researcher, Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
52, Krasny Ave., Novosibirsk, 630091,
175/1, B. Bogatkov St., Novosibirsk, 630089
G. G. Ketova
South Ural State Medical University
Russian Federation
Russian Federation
Galina G. Ketova, Dr. Sci. (Med.), Professor, Professor of the Department of Outpatient Therapy and Clinical Pharmacology
64, Vorovskiy St., Chelyabinsk, 454092
I. M. Martynenko
Pacific State Medical University
Russian Federation
Russian Federation
Irina M. Martynenko, Cand. Sci. (Med.), Associate Professor, Institute of Therapy and Instrumental Diagnostics
2, Ostriakov Ave., Vladivostok, 690002
I. F. Krotkova
Russian Medical Academy of Continuous Professional Education
Russian Federation
Russian Federation
Irina F. Krotkova, Cand. Sci. (Med.), Associated Professor of the Department of Therapy
2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993
E. Yu. Ebzeeva
Russian Medical Academy of Continuous Professional Education
Russian Federation
Russian Federation
Elizaveta Yu. Ebzeeva, Cand. Sci. (Med.), Associated Professor of the Department of Therapy
2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993
G. M. Bikkinina
Bashkir State Medical University
Russian Federation
Russian Federation
Guzel M. Bikkinina, Dr. Sci. (Med.), Professor, The Department of Pharmacology with the Course of Clinical Pharmacology
3, Lenin St., Ufa, 450000
I. K. Suvanov
Mari State University
Russian Federation
Russian Federation
Ibrokhimjon K. Suvanov, Student of the Medical Institute
1, Lenin St., Yoshkar-Ola, Mari El Republic, 424000
E. A. Shabanov
Kursk State Medical University
Russian Federation
Russian Federation
Evgeniy A. Shabanov, Cand. Sci. (Med.), Associated Professor of the Department of Internal Medicine Faculty of Postgraduate Education
3, Marx St., Kursk, 305041
G. G. Prozorova
Voronezh State Medical University named after N.N. Burdenko
Russian Federation
Russian Federation
Galina G. Prozorova, Dr. Sci. (Med.), Professor of the Department of Therapeutic Disciplines of the Institute of Additional Education
10, Studencheskaya St., Voronezh, 394036
U. M. Tilekeeva
Kyrgyz State Medical Academy
Kyrgyzstan
Kyrgyzstan
Ulankul M. Tilekeeva, Dr. Sci. (Med.), Professor Head of the Department of Basic and Clinical Pharmacology
92, Akhunbaev St., Bishkek, 720020
O. G. Kompaniets
Kuban State Medical University
Russian Federation
Russian Federation
Olga G. Kompaniets, Cand. Sci. (Med.), Chief Clinical Pharmacologist of Krasnodar City, Associated Professor of the Department of Therapy No. 1
4, Sedin St., Krasnodar, 350063
E. N. Bochanova
Krasnoyarsk State Medical University named after Professor V. F. Voino-Yasenetsky
Russian Federation
Russian Federation
Elena N. Bochanova, Dr. Sci. (Med.), Associated Professor of the Department of Pharmacology and Pharmaceutical Consulting with a Postgraduate Education Course
1, Partizan Zheleznyak St., Krasnoyarsk, 660022
E. V. Luchinina
Saratov State Medical University named after V.I. Razumovsky
Russian Federation
Russian Federation
Elena V. Luchinina, Cand. Sci. (Med.), Associated Professor of the Department of Clinical Pharmacology
112, Bolshaya Kazachia St., Saratov, 410012
M. L. Maximov
Kazan State Medical Academy – a branch of the Russian Medical Academy of Continuing Professional Education;
Novosibirsk State Medical University;
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Maxim L. Maximov, Dr. Sci. (Med.), Professor, Head of the Department of Clinical Pharmacology and Pharmacotherapy, Kazan State Medical Academy – branch of the Russian Medical Academy of Continuing Professional Education; Professor of the Department of Pharmacology of the Institute of Pharmacy and Medical Chemistry, Pirogov Russian National Research Medical University; Dean of the Faculty of Preventive Medicine and Health Care Organization, Russian Medical Academy of Continuous Professional Education
36, Butlerov St., Kazan, 420012,
1, Ostrovityanov St., Moscow, 117997,
2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993
References
1. Venkatesan P. GOLD COPD report: 2024 update. Lancet Respir Med. 2024;12(1):15–16. https://doi.org/10.1016/S2213-2600(23)00461-7.
2. Buist AS, Vollmer WM, Sullivan SD, Weiss KB, Lee TA, Menezes AM et al. The Burden of Obstructive Lung Disease Initiative (BOLD): Rationale and Design. COPD: 2005;2(2):277–283. Available at: https://pubmed.ncbi.nlm.nih.gov/17136954/.
3. Chuchalin AG, Khaltaev N, Antonov NS, Galkin DV, Manakov LG, Antonini P et al. Chronic respiratory diseases and risk factors in 12 regions of the Russian Federation. Int J Chron Obstruct Pulmon Dis. 2014;9:963–974. https://doi.org/10.2147/COPD.S67283.
4. Bontsevich RA, Shchurovskaya KV, Pokrovskaya TG, Goncharova NYu, Batisheva GA, Barysheva VO et al. Estimation of basic knowledge of COPD issues in graduate students – final results of ASCO study. Farmateka. 2018;8:72–78. (In Russ.) https://doi.org/10.18565/pharmateca.2018.8.72-78.
5. Bontsevich RA, Shershneva AS, Vovk YR, Filinichenko TS, Prozorova GG, Kirichenko AA et al. Chronic obstructive pulmonary disease: assessment of the knowledge of therapeutic doctors. The results of the ASCO-II study. Vrach. 2020;31(7):68–74. (In Russ.) https://doi.org/10.29296/25877305-2020-07-13.
6. Bontsevich RA, Adonina AV, Vovk YR, Batisheva GA, Cherenkova OV, Ketova GG et al. Management of Chronic Obstructive Pulmonary Disease. Arch Razi Inst. 2022;77(1):439–447. https://doi.org/10.22092/ari.2021.356613.1882.
7. Чучалин АГ, Авдеев СН, Айсанов ЗР, Белевский АС, Лещенко ИВ, Овчаренко СИ и др. Хроническая обструктивная болезнь легких: клинические рекомендации. 2018. Режим доступа: https://cr.minzdrav.gov.ru/archive.
8. Singh D, Agusti A, Anzueto A, Barnes PJ, Bourbeau J, Celli BR et al. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019. Eur Respir J. 2019;53(5):1900164. https://doi.org/10.1183/13993003.00164-2019.
9. Авдеев СН, Айсанов ЗР, Ардашева ТВ, Белевский АС, Демко ИВ, Зайцев АА и др. Хроническая обструктивная болезнь легких: клинические рекомендации. 2023. Режим доступа: https://spulmo.ru/upload/kr/HOBL_2023_draft.pdf.
10. Karchevskaya NA, Belevskiy AS. α1-Antitrypsin deficiency. Pulmonologiya. 2024;34(2):225–229. (In Russ.) https://doi.org/10.18093/08690189-2024-34-2-225-229.
11. Miravitlles M, Dirksen A, Ferrarotti I, Koblizek V, Lange P, Mahadeva R et al. European Respiratory Society statement: diagnosis and treatment of pulmonary disease in α1 -antitrypsin deficiency. Eur Respir J. 2017;50(5):1700610. https://doi.org/10.1183/13993003.00610-2017.
12. Guo P, Li R, Piao TH, Wang CL, Wu XL, Cai HY. Pathological Mechanism and Targeted Drugs of COPD. Int J Chron Obstruct Pulmon Dis. 2022;17:1565–1575. https://doi.org/10.2147/COPD.S366126.
13. Каменева МЮ, Черняк АВ, Айсанов ЗР, Перельман ЮМ, Приходько АГ, Чушкин МИ и др. Спирометрия. 2023. Режим доступа: https://spulmo.ru/upload/kr/Spirometria_2023.pdf?t=1.
14. Agustí A, Celli BR, Criner GJ, Halpin D, Anzueto A, Barnes P et al. Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. Eur Respir J. 2023;61(4):2300239. https://doi.org/10.1183/13993003.00239-2023.
15. Chuchalin AG, Briko NI, Avdeev SN, Belevskiy AS, Bilichenko TN, Demko IV et al. Federal Clinical Guidelines on Preventive Vaccination Against Pneumococcal infections in Adults. Pulmonologiya. 2019;29(1):19–34. (In Russ.) https://doi.org/10.18093/0869-0189-2019-29-1-19-34.
16. Boytsov SA, Loukianov MM, Platonova EV, Gorbunov VM, Romanchuk SV, Nazarova OA et al. Efficiency of influenza vaccination in patients with circulatory system diseases under dispensary observation in outpatient clinics: prospective follow-up monitoring data. Rational Pharmacotherapy in Cardiology. 2016;12(6):703–710. (In Russ.) https://doi.org/10.20996/1819-6446-2016-12-6-703-710.
17. Huang CL, Nguyen PA, Kuo PL, Iqbal U, Hsu YH, Jian WS. Influenza vaccination and reduction in risk of ischemic heart disease among chronic obstructive pulmonary elderly. Comput Methods Programs in Biomed. 2013;111(2):507–511. https://doi.org/10.1016/j.cmpb.2013.05.006.
18. Warren-Gash C, Smeeth L, Hayward AC. Influenza as a trigger for acute myocardial infarction or death from cardiovascular disease: a systematic review. Lancet Infect Dis. 2009;9(10):601–610. https://doi.org/10.1016/S1473-3099(09)70233-6.
19. Surmachevska N, Tiwari V. Corticosteroid Induced Myopathy. StatPearls. Treasure Island (FL): StatPearls Publishing; 2024. Available at: https://pubmed.ncbi.nlm.nih.gov/32491663/.
20. Pereira RMR, Freire de Carvalho J. Glucocorticoid-induced myopathy. Joint Bone Spine. 2011;78(1):41–44. https://doi.org/10.1016/j.jbspin.2010.02.025.
21. Maksimov ML, Bontsevich RA, Shikaleva AA. Treatment of exacerbations of chronic obstructive pulmonary disease. Therapist. 2024;(12):46–55. (In Russ.) https://doi.org/10.33920/MED-12-2412-06.
Review
For citations:
Bontsevich RA, Zavitkevich GI, Batishcheva GA, Nevzorova VA, Tsygankova OV, Ketova GG, Martynenko IM, Krotkova IF, Ebzeeva EY, Bikkinina GM, Suvanov IK, Shabanov EA, Prozorova GG, Tilekeeva UM, Kompaniets OG, Bochanova EN, Luchinina EV, Maximov ML. Etiology, pathogenesis and diagnosis of chronic obstructive pulmonary disease: Assessment of the knowledge of doctors and senior students. Results of the ASCO-III study. Meditsinskiy sovet = Medical Council. 2025;(9):69-79. (In Russ.) https://doi.org/10.21518/ms2025-037
Views:
173
Email this article 