Criteria for classifying children into risk groups according to atherosclerotic cardiovascular diseases
I. I. Pshenichnikova,
M. V. Ezhov,
I. I. Trunina,
I. M. Osmanov,
A. V. Miroshina,
S. N. Borzakova,
I. N. Zakharova https://doi.org/10.21518/ms2025-275
Abstract
Atherosclerosis, which begins early in life, accounts for a significant share of cardiovascular diseases in adulthood. At the same time, the prevalence of obesity, high blood pressure and dyslipidemia among children in certain regions of the Russian Federation reaches double figures. New order No. 211n of the Ministry of Health of Russia provides for the targeted lipid screening of children aged 6 and 10 years, however specific clinical and anamnestic grounds and criteria for being qualified as children at risk have not yet been regulated. This paper presents an analytical review of federal regulatory acts, current clinical guidelines and national multicenter studies (2014–2024), which gave rise to a list of indications for targeted screening for lipid profile in children and adolescents. The proposed checklist includes 17 clinical, anamnestic and phenotypic criteria grouped into eight blocks: (1) hereditary predisposition, (2) phenotypic markers for hyperlipidemia, (3) the presence of overweight/obesity, (4) resistant hypertension, (5) severe metabolic and systemic diseases, (6) congenital and acquired valvular heart diseases, (7) modifiable behavioural factors, (8) earlier cardiotoxic conditions. The presence of one key or two additional symptoms serves as a basis for an extended lipid panel testing and subsequent follow-up care. The presented model does not have a regulatory status and reflects the point of view of the authors' team; it is intended for expert discussion, improvement and further clinical validation. The proposed tool can be easily integrated into electronic health records, automating patient routing and creating the groundwork for prospective studies of Russian pediatric cohorts.
About the Authors
I. I. Pshenichnikova
Russian Medical Academy of Continuous Professional Education; Bashlyaeva Children’s City Clinical Hospital; Research Institute of Healthcare Organization and Medical Management
Russian Federation
Russian Federation
Irina I. Pshenichnikova - Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics named after Academician G.N. Speransky, Russian Medical Academy of Continuing Professional Education; Paediatrician, Bashlyaeva Children’s City Clinical Hospital; Specialist of the Organizational and Methodical Department of Paediatrics, Research Institute of Healthcare Organization and Medical Management.
2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993; 28, Geroyev Panfilovtsev St., Moscow, 125373; 9, Sharikopodshipnikovskaya St., Moscow, 115088
M. V. Ezhov
National Medical Research Centre of Cardiology named after Academician E.I. Chazov
Russian Federation
Russian Federation
Marat V. Ezhov - Dr. Sci. (Med.), Professor, Chief Researcher, Laboratory of Lipid Metabolism Disorders, Myasnikov Research Institute of Clinical Cardiology, National Medical Research Centre of Cardiology named after Academician E.I. Chazov.
15a, Academician Chazov St., Moscow, 121552
I. I. Trunina
Bashlyaeva Children’s City Clinical Hospital; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Inna I. Trunina - Dr. Sci. (Med.), Professor, Head of the Cardiology Department, Bashlyaeva Children’s City Clinical Hospital; Professor of Department of Hospital Paediatrics No 1, Faculty of Paediatrics, Pirogov Russian National Research Medical University.
28, Geroyev Panfilovtsev St., Moscow, 125373; 2, Taldomskaya St., Moscow, 125412
I. M. Osmanov
Russian Medical Academy of Continuous Professional Education; Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Ismail M. Osmanov - Dr. Sci. (Med.), Professor, Chief Physician, Bashlyaeva Moscow Children’s City Clinical Hospital; Professor, Department of Paediatrics No. 2, Faculty of Paediatrics, Pirogov Russian National Research Medical University.
28, Geroyev Panfilovtsev St., Moscow, 125373; 2, Taldomskaya St., Moscow, 125412
A. V. Miroshina
Bashlyaeva Children’s City Clinical Hospital; Research Institute of Healthcare Organization and Medical Management
Russian Federation
Russian Federation
Aleksandra V. Miroshina - Head of Organisational-Analytical Department, Bashlyaeva Moscow Children’s City Clinical Hospital; Analyst, Organisational-Methodological Department for Paediatrics, Research Institute for Healthcare Organisation and Medical Management, Moscow Healthcare Department.
28, Geroyev Panfilovtsev St., Moscow, 125373; 9, Sharikopodshipnikovskaya St., Moscow, 115088
S. N. Borzakova
Russian Medical Academy of Continuous Professional Education; Bashlyaeva Children’s City Clinical Hospital; Research Institute of Healthcare Organization and Medical Management
Russian Federation
Russian Federation
Svetlana N. Borzakova - Cand. Sci. (Med.), Associate Professor, Department of Paediatrics named after Academician G.N. Speransky, Russian Medical Academy of Continuing Professional Education; Head, Organisational-Methodological Department for Paediatrics, Research Institute for Healthcare Organisation and Medical Management, Moscow Healthcare Department; Paediatric Gastroenterologist, Bashlyaeva Moscow Children’s City Clinical Hospital.
2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993; 9, Sharikopodshipnikovskaya St., Moscow, 115088; 28, Geroyev Panfilovtsev St., Moscow, 125373
I. N. Zakharova
Russian Medical Academy of Continuous Professional Education
Russian Federation
Russian Federation
Irina N. Zakharova - Dr. Sci. (Med.), Professor, Head of the Department of Pediatrics named after G.N. Speransky, Russian Medical Academy of Continuous Professional Education.
2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993
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For citations:
Pshenichnikova II, Ezhov MV, Trunina II, Osmanov IM, Miroshina AV, Borzakova SN, Zakharova IN. Criteria for classifying children into risk groups according to atherosclerotic cardiovascular diseases. Meditsinskiy sovet = Medical Council. 2025;(11):206-211. (In Russ.) https://doi.org/10.21518/ms2025-275
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